Bi-and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples EM Scott, EJ Jacobus, B Lyons, S Frost, JD Freedman, A Dyer, ... Journal for ImmunoTherapy of Cancer 7, 1-18, 2019 | 77 | 2019 |
Antagonism of glycolysis and reductive carboxylation of glutamine potentiates activity of oncolytic adenoviruses in cancer cells A Dyer, B Schoeps, S Frost, P Jakeman, EM Scott, J Freedman, ... Cancer Research 79 (2), 331-345, 2019 | 47 | 2019 |
Tumor-free transplantation of patient-derived induced pluripotent stem cell progeny for customized islet regeneration MM El Khatib, S Ohmine, EJ Jacobus, JM Tonne, SG Morsy, SJ Holditch, ... Stem cells translational medicine 5 (5), 694-702, 2016 | 43 | 2016 |
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy ME Wedge, VA Jennings, MJF Crupi, J Poutou, T Jamieson, A Pelin, ... Nature communications 13 (1), 1898, 2022 | 38 | 2022 |
Impaired β-cell glucokinase as an underlying mechanism in diet-induced diabetes B Lu, K Kurmi, M Munoz-Gomez, EJ Jacobus Ambuludi, JM Tonne, ... Disease models & mechanisms 11 (6), dmm033316, 2018 | 28 | 2018 |
Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference A Dyer, R Baugh, SL Chia, S Frost, Iris, EJ Jacobus, H Khalique, ... Cancer gene therapy 26 (3), 59-73, 2019 | 26 | 2019 |
Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells J Lei, EJ Jacobus, WK Taverner, KD Fisher, S Hemmi, K West, L Slater, ... Journal for immunotherapy of cancer 6, 1-16, 2018 | 20 | 2018 |
External beam radiation therapy and enadenotucirev: Inhibition of the DDR and mechanisms of radiation-mediated virus increase TD Pokrovska, EJ Jacobus, R Puliyadi, R Prevo, S Frost, A Dyer, R Baugh, ... Cancers 12 (4), 798, 2020 | 18 | 2020 |
Attenuation of the hypoxia inducible factor pathway after oncolytic adenovirus infection coincides with decreased vessel perfusion I Yousaf, J Kaeppler, S Frost, LW Seymour, EJ Jacobus Cancers 12 (4), 851, 2020 | 15 | 2020 |
Reducing cell intrinsic immunity to mRNA vaccine alters adaptive immune responses in mice Z Wang, EJ Jacobus, DC Stirling, S Krumm, KE Flight, RF Cunliffe, J Mottl, ... Molecular Therapy-Nucleic Acids 34, 2023 | 12 | 2023 |
Calcium influx caused by ER stress inducers enhances oncolytic adenovirus enadenotucirev replication and killing through PKCα activation WK Taverner, EJ Jacobus, J Christianson, B Champion, AW Paton, ... Molecular Therapy-Oncolytics 15, 117-130, 2019 | 11 | 2019 |
The dual influence of tumour hypoxia on the activity of a group B oncolytic adenoviurs E Jacobus Ambuludi University of Oxford, 2018 | | 2018 |
Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference TD Pokrovska, EM Scott, WK Taverner, LW Seymour, J Lei | | 2018 |
Glucokinase Overexpression Enhances Beta-Cell Proliferation or Beta-Cell Function Depending on Age and Diet B Lu, K Kurmi, MJ Munoz-Gomez, EJJ Ambuludi, JM Tonne, T Hitosugi, ... DIABETES 66, A575-A575, 2017 | | 2017 |
Tailored Oncolytic Viral Therapeutics for Pancreatic Cancer CS Ilkow, E Jacobus, B Weatherall, D Roy, B tenOever, JC Bell HUMAN GENE THERAPY 25 (12), A21-A21, 2014 | | 2014 |
Pancreas-Targeted Gene Delivery for Enhanced Beta-Cell Proliferation B Lu, JM Tonne, K Kurmi, M Munoz-Gomez, E Jacobus, Y Kudva, Y Ikeda MOLECULAR THERAPY 22, S228-S228, 2014 | | 2014 |
Lentivector-Mediated c-MYC Expression Plays a Key Role in Consistent Teratoma Formation upon Transplantation of iPSC-Derived Progenitor Cells Y Ikeda, M El-Khatib, O Seiga, E Jacobus, J Tonne, Y Kudva MOLECULAR THERAPY 22, S80-S80, 2014 | | 2014 |
Supplementary Materials: External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase TD Pokrovska, EJ Jacobus, R Puliyadi, R Prevo, S Frost, A Dyer, R Baugh, ... | | |
Supplementary Materials: Attenuation of the Hypoxia Inducible Factor Pathway after Oncolytic Adenovirus Infection Coincides with Decreased Vessel Perfusion I Yousaf, J Kaeppler, S Frost, LW Seymour, EJ Jacobus | | |