Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor A Rauch, S Seitz, U Baschant, AF Schilling, A Illing, B Stride, M Kirilov, ... Cell metabolism 11 (6), 517-531, 2010 | 442 | 2010 |
Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis A Rauch, AK Haakonsson, JGS Madsen, M Larsen, I Forss, MR Madsen, ... Nature genetics 51 (4), 716-727, 2019 | 185 | 2019 |
Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo HW Lim, NH Uhlenhaut, A Rauch, J Weiner, S Hübner, N Hübner, KJ Won, ... Genome research 25 (6), 836-844, 2015 | 178 | 2015 |
DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Krüppel-like factor 15 gene expression M Asada, A Rauch, H Shimizu, H Maruyama, S Miyaki, M Shibamori, ... Laboratory investigation 91 (2), 203-215, 2011 | 113 | 2011 |
Obesity-associated hypermetabolism and accelerated senescence of bone marrow stromal stem cells suggest a potential mechanism for bone fragility M Tencerova, M Frost, F Figeac, TK Nielsen, D Ali, JJL Lauterlein, ... Cell Reports 27 (7), 2050-2062. e6, 2019 | 99 | 2019 |
An anti‐inflammatory selective glucocorticoid receptor modulator preserves osteoblast differentiation A Rauch, V Gossye, D Bracke, E Gevaert, P Jacques, K Van Beneden, ... The FASEB Journal 25 (4), 1323-1332, 2011 | 90 | 2011 |
Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities LO Huang, A Rauch, E Mazzaferro, M Preuss, S Carobbio, CS Bayrak, ... Nature Metabolism 3 (2), 228-243, 2021 | 80 | 2021 |
Highly interconnected enhancer communities control lineage-determining genes in human mesenchymal stem cells JGS Madsen, MS Madsen, A Rauch, S Traynor, EL Van Hauwaert, ... Nature Genetics 52 (11), 1227-1238, 2020 | 65 | 2020 |
Loss of menin in osteoblast lineage affects osteocyte–osteoclast crosstalk causing osteoporosis P Liu, S Lee, J Knoll, A Rauch, S Ostermay, J Luther, N Malkusch, ... Cell Death & Differentiation 24 (4), 672-682, 2017 | 63 | 2017 |
Integrated analysis of motif activity and gene expression changes of transcription factors JGS Madsen, A Rauch, EL Van Hauwaert, SF Schmidt, M Winnefeld, ... Genome research 28 (2), 243-255, 2018 | 52 | 2018 |
Transcriptional networks controlling stromal cell differentiation A Rauch, S Mandrup Nature Reviews Molecular Cell Biology 22 (7), 465-482, 2021 | 35 | 2021 |
Instructions for producing a mouse model of glucocorticoid-induced osteoporosis S Thiele, U Baschant, A Rauch, M Rauner BoneKEy reports 3, 2014 | 31 | 2014 |
Impaired bone fracture healing in type 2 diabetes is caused by defective functions of skeletal progenitor cells F Figeac, M Tencerova, D Ali, TL Andersen, DRC Appadoo, G Kerckhofs, ... Stem cells 40 (2), 149-164, 2022 | 23 | 2022 |
Classical and alternative NF-κB signaling cooperate in regulating adipocyte differentiation and function A Weidemann, A Lovas, A Rauch, N Andreas, J Von Maltzahn, ... International Journal of Obesity 40 (3), 452-459, 2016 | 22 | 2016 |
High‐fat diet‐induced obesity augments the deleterious effects of estrogen deficiency on bone: Evidence from ovariectomized mice D Ali, F Figeac, A Caci, N Ditzel, C Schmal, G Kerckhofs, J Havelund, ... Aging Cell 21 (12), e13726, 2022 | 20 | 2022 |
In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice E Chichelnitskiy, A Vegiopoulos, MB Diaz, A Ziegler, A Kleiman, A Rauch, ... Hepatology 50 (6), 1963-1971, 2009 | 19 | 2009 |
Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators M Ahmad, T Kroll, J Jakob, A Rauch, A Ploubidou, J Tuckermann Scientific Reports 8 (1), 14045, 2018 | 16 | 2018 |
ERG controls B cell development by promoting Igh V-to-DJ recombination E Søndergaard, A Rauch, M Michaut, N Rapin, M Rehn, AS Wilhelmson, ... Cell Reports 29 (9), 2756-2769. e6, 2019 | 12 | 2019 |
Time-resolved systems medicine reveals viral infection-modulating host targets C Wiwie, I Kuznetsova, A Mostafa, A Rauch, A Haakonsson, ... Systems Medicine 2 (1), 1-9, 2019 | 12 | 2019 |
Glucocorticoid activation of anti-inflammatory macrophages protects against insulin resistance G Caratti, U Stifel, B Caratti, AJM Jamil, KJ Chung, M Kiehntopf, ... Nature communications 14 (1), 2271, 2023 | 11 | 2023 |