Type 1 diabetes LA DiMeglio, C Evans-Molina, RA Oram The Lancet 391 (10138), 2449-2462, 2018 | 1526 | 2018 |
Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene SM Edwards, Z Kote-Jarai, J Meitz, R Hamoudi, Q Hope, P Osin, ... The American Journal of Human Genetics 72 (1), 1-12, 2003 | 451 | 2003 |
Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank NJ Thomas, SE Jones, MN Weedon, BM Shields, RA Oram, AT Hattersley The lancet Diabetes & endocrinology 6 (2), 122-129, 2018 | 431 | 2018 |
Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040: a modelling study GA Gregory, TIG Robinson, SE Linklater, F Wang, S Colagiuri, ... The lancet Diabetes & endocrinology 10 (10), 741-760, 2022 | 403 | 2022 |
The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells RA Oram, AG Jones, REJ Besser, BA Knight, BM Shields, RJ Brown, ... Diabetologia 57, 187-191, 2014 | 336 | 2014 |
A type 1 diabetes genetic risk score can aid discrimination between type 1 and type 2 diabetes in young adults RA Oram, K Patel, A Hill, B Shields, TJ McDonald, A Jones, AT Hattersley, ... Diabetes care 39 (3), 337-344, 2016 | 333 | 2016 |
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial RECOVERY Collaborative Group Lancet (London, England) 397 (10274), 605, 2021 | 321 | 2021 |
Introducing the endotype concept to address the challenge of disease heterogeneity in type 1 diabetes M Battaglia, S Ahmed, MS Anderson, MA Atkinson, D Becker, PJ Bingley, ... Diabetes care 43 (1), 5-12, 2020 | 269 | 2020 |
Systematic population screening, using biomarkers and genetic testing, identifies 2.5% of the UK pediatric diabetes population with monogenic diabetes M Shepherd, B Shields, S Hammersley, M Hudson, TJ McDonald, ... Diabetes care 39 (11), 1879-1888, 2016 | 242 | 2016 |
Development and standardization of an improved type 1 diabetes genetic risk score for use in newborn screening and incident diagnosis SA Sharp, SS Rich, AR Wood, SE Jones, RN Beaumont, JW Harrison, ... Diabetes care 42 (2), 200-207, 2019 | 241 | 2019 |
An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy MN Weedon, S Ellard, MJ Prindle, R Caswell, HL Allen, R Oram, ... Nature genetics 45 (8), 947-950, 2013 | 174 | 2013 |
Type 1 diabetes genetic risk score: a novel tool to discriminate monogenic and type 1 diabetes KA Patel, RA Oram, SE Flanagan, E De Franco, K Colclough, M Shepherd, ... Diabetes 65 (7), 2094-2099, 2016 | 153 | 2016 |
Most people with long-duration type 1 diabetes in a large population-based study are insulin microsecretors RA Oram, TJ McDonald, BM Shields, MM Hudson, MH Shepherd, ... Diabetes care 38 (2), 323-328, 2015 | 152 | 2015 |
100 years of insulin: celebrating the past, present and future of diabetes therapy EK Sims, ALJ Carr, RA Oram, LA DiMeglio, C Evans-Molina Nature medicine 27 (7), 1154-1164, 2021 | 141 | 2021 |
Type 1 diabetes defined by severe insulin deficiency occurs after 30 years of age and is commonly treated as type 2 diabetes NJ Thomas, AL Lynam, AV Hill, MN Weedon, BM Shields, RA Oram, ... Diabetologia 62 (7), 1167-1172, 2019 | 138 | 2019 |
A type 1 diabetes genetic risk score predicts progression of islet autoimmunity and development of type 1 diabetes in individuals at risk MJ Redondo, S Geyer, AK Steck, S Sharp, JM Wentworth, MN Weedon, ... Diabetes care 41 (9), 1887-1894, 2018 | 137 | 2018 |
The clinical consequences of heterogeneity within and between different diabetes types MJ Redondo, WA Hagopian, R Oram, AK Steck, K Vehik, M Weedon, ... Diabetologia 63, 2040-2048, 2020 | 130 | 2020 |
Hepatocyte nuclear factor-1β gene deletions—a common cause of renal disease EL Edghill, RA Oram, M Owens, KL Stals, LW Harries, AT Hattersley, ... Nephrology Dialysis Transplantation 23 (2), 627-635, 2008 | 129 | 2008 |
Beta cells in type 1 diabetes: mass and function; sleeping or dead? RA Oram, EK Sims, C Evans-Molina Diabetologia 62, 567-577, 2019 | 128 | 2019 |
Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis P Leete, RA Oram, TJ McDonald, BM Shields, C Ziller, ... Diabetologia 63, 1258-1267, 2020 | 126 | 2020 |