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Nigel O'Neil
Nigel O'Neil
Research Associate, University of British Columbia
在 msl.ubc.ca 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Synthetic lethality and cancer
NJ O'Neil, ML Bailey, P Hieter
Nature Reviews Genetics 18 (10), 613-623, 2017
6392017
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
D Bergamaschi, Y Samuels, NJ O'Neil, G Trigiante, T Crook, JK Hsieh, ...
Nature genetics 33 (2), 162-167, 2003
5272003
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
Nature communications 8 (1), 14432, 2017
5182017
RTEL1 maintains genomic stability by suppressing homologous recombination
LJ Barber, JL Youds, JD Ward, MJ McIlwraith, NJ O'Neil, MIR Petalcorin, ...
Cell 135 (2), 261-271, 2008
4592008
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes
M Le Gallo, AJ O'Hara, ML Rudd, ME Urick, NF Hansen, NJ O'Neil, ...
Nature genetics 44 (12), 1310-1315, 2012
4292012
RTEL-1 enforces meiotic crossover interference and homeostasis
JL Youds, DG Mets, MJ McIlwraith, JS Martin, JD Ward, NJ ONeil, ...
Science 327 (5970), 1254-1258, 2010
2012010
MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genome
JR Tyson, NJ O'Neil, M Jain, HE Olsen, P Hieter, TP Snutch
Genome research 28 (2), 266-274, 2018
1692018
DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair
JL Youds, LJ Barber, JD Ward, SJ Collis, NJ O'Neil, SJ Boulton, AM Rose
Molecular and cellular biology 28 (5), 1470-1479, 2008
1162008
The use of functional genomics in C. elegans for studying human development and disease
PE Kuwabara, N O'neil
Journal of inherited metabolic disease 24 (2), 127-138, 2001
1032001
TILLING is an effective reverse genetics technique for Caenorhabditis elegans
EJ Gilchrist, NJ O'Neil, AM Rose, MC Zetka, GW Haughn
BMC genomics 7, 1-16, 2006
1002006
Glioblastoma Cells Containing Mutations in the Cohesin Component STAG2 Are Sensitive to PARP Inhibition
ML Bailey, NJ O'Neil, DM van Pel, DA Solomon, T Waldman, P Hieter
Molecular cancer therapeutics 13 (3), 724-732, 2014
892014
Synthetic lethality of cohesins with PARPs and replication fork mediators
JL McLellan, NJ O'Neil, I Barrett, E Ferree, DM van Pel, K Ushey, ...
PLoS genetics 8 (3), e1002574, 2012
882012
Joint Molecule Resolution Requires the Redundant Activities of MUS-81 and XPF-1 during Caenorhabditis elegans Meiosis
NJ O'Neil, JS Martin, JL Youds, JD Ward, MIR Petalcorin, AM Rose, ...
PLoS genetics 9 (7), e1003582, 2013
802013
Homologous Recombination Is Required for Genome Stability in the Absence of DOG-1 in Caenorhabditis elegans
JL Youds, NJ O'Neil, AM Rose
Genetics 173 (2), 697-708, 2006
802006
Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1
JW Astin, NJ O’Neil, PE Kuwabara
DNA repair 7 (2), 267-280, 2008
662008
The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans
LM Kuervers, CL Jones, NJ O'neil, DL Baillie
Molecular Genetics and Genomics 270, 121-131, 2003
652003
Identification and analysis of internal promoters in Caenorhabditis elegans operons
P Huang, ED Pleasance, JS Maydan, R Hunt-Newbury, NJ O’Neil, A Mah, ...
Genome research 17 (10), 1478-1485, 2007
612007
Synthetic Lethal Genetic Interactions That Decrease Somatic Cell Proliferation in Caenorhabditis elegans Identify the Alternative RFCCTF18 as a Candidate …
J McLellan, N O'Neil, S Tarailo, J Stoepel, J Bryan, A Rose, P Hieter
Molecular biology of the cell 20 (24), 5306-5313, 2009
532009
Synthetic lethality and cancer: cohesin and PARP at the replication fork
NJ O’Neil, DM van Pel, P Hieter
Trends in Genetics 29 (5), 290-297, 2013
462013
RNA-mediated interference as a tool for identifying drug targets
NJ O’Neil, RL Martin, ML Tomlinson, MR Jones, A Coulson, PE Kuwabara
American Journal of Pharmacogenomics 1, 45-53, 2001
452001
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