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Pablo Martín-Gago
Pablo Martín-Gago
LEO Pharma
在 leo-pharma.com 的电子邮件经过验证
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引用次数
引用次数
年份
Identification of pyrazolopyridazinones as PDEδ inhibitors
B Papke, S Murarka, HA Vogel, P Martín-Gago, M Kovacevic, DC Truxius, ...
Nature communications 7 (1), 11360, 2016
1732016
Stereoconvergent arylations and alkenylations of unactivated alkyl electrophiles: catalytic enantioselective synthesis of secondary sulfonamides and sulfones
J Choi, P Martín-Gago, GC Fu
Journal of the American Chemical Society 136 (34), 12161-12165, 2014
1572014
Arylfluorosulfate‐based electrophiles for covalent protein labeling: a new addition to the arsenal
P Martín‐Gago, CA Olsen
Angewandte Chemie International Edition 58 (4), 957-966, 2019
1232019
A PDE6δ‐KRas inhibitor chemotype with up to seven H‐bonds and picomolar affinity that prevents efficient inhibitor release by Arl2
P Martín‐Gago, EK Fansa, CH Klein, S Murarka, P Janning, M Schürmann, ...
Angewandte Chemie 129 (9), 2463-2468, 2017
962017
Covalent protein labeling at glutamic acids
P Martín-Gago, EK Fansa, M Winzker, S Murarka, P Janning, ...
Cell chemical biology 24 (5), 589-597. e5, 2017
822017
MaxPHOS Ligand: PH/NH Tautomerism and Rhodium‐Catalyzed Asymmetric Hydrogenations
E Cristóbal‐Lecina, P Etayo, S Doran, M Reves, P Martín‐Gago, ...
Advanced synthesis & catalysis 356 (4), 795-804, 2014
732014
A tetradecapeptide somatostatin dicarba-analog: Synthesis, structural impact and biological activity
P Martín-Gago, R Ramón, E Aragón, J Fernández-Carneado, ...
Bioorganic & medicinal chemistry letters 24 (1), 103-107, 2014
352014
Gas-phase collision induced dissociation mechanisms of peptides: Theoretical and experimental study of N-formylalanylamide fragmentation
D Ortiz, P Martin-Gago, A Riera, K Song, JY Salpin, R Spezia
International Journal of Mass Spectrometry 335, 33-44, 2013
342013
Development of pyridazinone chemotypes targeting the PDEδ prenyl binding site
S Murarka, P Martín‐Gago, C Schultz‐Fademrecht, A Al Saabi, ...
Chemistry–A European Journal 23 (25), 6083-6093, 2017
312017
PDEδ inhibition impedes the proliferation and survival of human colorectal cancer cell lines harboring oncogenic KRas
CH Klein, DC Truxius, HA Vogel, J Harizanova, S Murarka, ...
International Journal of Cancer 144 (4), 767-776, 2019
302019
Fine-tuning the [Pi]-[Pi]. Aromatic interactions in peptides: somatostatin analogues containing mesityl alanine
P Martín-Gago, M Gomez-Caminals, R Ramón, X Verdaguer i Espaulella, ...
Angewandte Chemie-International Edition, 2012, vol. 51, num. 8, p. 1820-1825, 2012
302012
Aryl fluorosulfate based inhibitors that covalently target the SIRT5 lysine deacylase
JE Bolding, P Martín‐Gago, N Rajabi, LF Gamon, TN Hansen, ...
Angewandte Chemie International Edition 61 (47), e202204565, 2022
282022
Structure-based development of PDEδ inhibitors
P Martín-Gago, EK Fansa, A Wittinghofer, H Waldmann
Biological Chemistry 398 (5-6), 535-545, 2017
272017
Arylfluorsulfat‐basierte Elektrophile für die kovalente Proteinmarkierung
P Martín‐Gago, CA Olsen
Angewandte Chemie 131 (4), 969-978, 2019
222019
Insights into structure-activity relationships of somatostatin analogs containing mesitylalanine
P Martín-Gago, E Aragón, M Gomez-Caminals, J Fernández-Carneado, ...
Molecules 18 (12), 14564-14584, 2013
202013
SSTR1‐and SSTR3‐Selective Somatostatin Analogues
R Ramón, P Martín‐Gago, X Verdaguer, MJ Macias, P Martin‐Malpartida, ...
ChemBioChem 12 (4), 625-632, 2011
162011
Photo Cross‐Linking Probes Containing ϵ‐N‐Thioacyllysine and ϵ‐N‐Acyl‐(δ‐aza)lysine Residues
M Bæk, P Martín‐Gago, JS Laursen, JLH Madsen, S Chakladar, CA Olsen
Chemistry–A European Journal 26 (17), 3862-3869, 2020
152020
Peptide aromatic interactions modulated by fluorinated residues: Synthesis, structure and biological activity of Somatostatin analogs containing 3-(3′, 5′ difluorophenyl)-alanine
P Martín-Gago, Á Rol, T Todorovski, E Aragón, P Martin-Malpartida, ...
Scientific Reports 6 (1), 27285, 2016
112016
Nickel‐Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers
G Laudadio, P Neigenfind, Á Péter, CZ Rubel, MA Emmanuel, ...
Angewandte Chemie International Edition 63 (8), e202314617, 2024
72024
Ni-Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers
G Laudadio, P Neigenfind, Á Péter, CZ Rubel, MA Emmanuel, ...
42023
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