Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ... Journal of Neuroscience 29 (2), 359-370, 2009 | 1215 | 2009 |
Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status A Everard, L Geurts, R Caesar, M Van Hul, S Matamoros, T Duparc, ... Nature communications 5 (1), 5648, 2014 | 249 | 2014 |
Genetic deficiency of indoleamine 2, 3-dioxygenase promotes gut microbiota-mediated metabolic health L Laurans, N Venteclef, Y Haddad, M Chajadine, F Alzaid, S Metghalchi, ... Nature medicine 24 (8), 1113-1120, 2018 | 227 | 2018 |
Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity E Dalmas, A Toubal, F Alzaid, K Blazek, HL Eames, K Lebozec, M Pini, ... Nature medicine 21 (6), 610-618, 2015 | 181 | 2015 |
Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota L Geurts, A Everard, M Van Hul, A Essaghir, T Duparc, S Matamoros, ... Nature communications 6 (1), 6495, 2015 | 171 | 2015 |
Palatability can drive feeding independent of AgRP neurons RGP Denis, A Joly-Amado, E Webber, F Langlet, M Schaeffer, SL Padilla, ... Cell metabolism 22 (4), 646-657, 2015 | 154 | 2015 |
Peroxisome proliferator-activated receptor-γ-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status WT Festuccia, S Oztezcan, M Laplante, M Berthiaume, C Michel, S Dohgu, ... Endocrinology 149 (5), 2121-2130, 2008 | 150 | 2008 |
The hypothalamic arcuate nucleus and the control of peripheral substrates A Joly-Amado, C Cansell, RGP Denis, AS Delbes, J Castel, S Martinez, ... Best practice & research Clinical endocrinology & metabolism 28 (5), 725-737, 2014 | 139 | 2014 |
Hypothalamic AgRP‐neurons control peripheral substrate utilization and nutrient partitioning A Joly‐Amado, RGP Denis, J Castel, A Lacombe, C Cansell, C Rouch, ... The EMBO journal 31 (22), 4276-4288, 2012 | 132 | 2012 |
Short-term consumption of sucralose with, but not without, carbohydrate impairs neural and metabolic sensitivity to sugar in humans JR Dalenberg, BP Patel, R Denis, MG Veldhuizen, Y Nakamura, PC Vinke, ... Cell Metabolism 31 (3), 493-502. e7, 2020 | 125 | 2020 |
Signals of adiposity RG Vernon, RGP Denis, A Sørensen Domestic Animal Endocrinology 21 (4), 197-214, 2001 | 112 | 2001 |
Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high‐fat‐diet‐induced obesity J Auffret, S Viengchareun, N Carré, RGP Denis, C Magnan, PY Marie, ... The FASEB Journal 26 (9), 3728-3737, 2012 | 98 | 2012 |
Leptin and the adaptations of lactation in rodents and ruminants RG Vernon, RGP Denis, A Sorensen, G Williams Hormone and Metabolic Research 34 (11/12), 678-685, 2002 | 95 | 2002 |
Acyl-CoA-binding protein is a lipogenic factor that triggers food intake and obesity JM Bravo-San Pedro, V Sica, I Martins, J Pol, F Loos, MC Maiuri, ... Cell Metabolism 30 (4), 754-767. e9, 2019 | 91 | 2019 |
Arcuate AgRP neurons and the regulation of energy balance C Cansell, RGP Denis, A Joly-Amado, J Castel, S Luquet Frontiers in endocrinology 3, 169, 2012 | 90 | 2012 |
Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle E Mouisel, K Relizani, L Mille-Hamard, R Denis, C Hourdé, O Agbulut, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2014 | 89 | 2014 |
Regulation of serum leptin and its role in the hyperphagia of lactation in the rat RGP Denis, G Williams, RG Vernon Journal of Endocrinology 176 (2), 193-204, 2003 | 77 | 2003 |
Effects of rimonabant (SR141716) on fasting-induced hypothalamic-pituitary-adrenal axis and neuronal activation in lean and obese Zucker rats C Doyon, RG Denis, ED Baraboi, P Samson, J Lalonde, Y Deshaies, ... Diabetes 55 (12), 3403-3410, 2006 | 76 | 2006 |
A fat-enriched, glucose-enriched diet markedly attenuates adiponectin mRNA levels in rat epididymal adipose tissue EK Naderali, D Estadella, M Rocha, LC Pickavance, S Fatani, RGP Denis, ... Clinical Science 105 (4), 403-408, 2003 | 76 | 2003 |
TNF-α transiently induces endoplasmic reticulum stress and an incomplete unfolded protein response in the hypothalamus RG Denis, AP Arruda, T Romanatto, M Milanski, A Coope, C Solon, ... Neuroscience 170 (4), 1035-1044, 2010 | 71 | 2010 |