Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer U Sahin, E Derhovanessian, M Miller, BP Kloke, P Simon, M Löwer, ... Nature 547 (7662), 222-226, 2017 | 2297 | 2017 |
Mutant MHC class II epitopes drive therapeutic immune responses to cancer S Kreiter, M Vormehr, N Van de Roemer, M Diken, M Löwer, J Diekmann, ... Nature 520 (7549), 692-696, 2015 | 1342 | 2015 |
Key parameters of tumor epitope immunogenicity revealed through a consortium approach improve neoantigen prediction DK Wells, MM van Buuren, KK Dang, VM Hubbard-Lucey, KCF Sheehan, ... Cell 183 (3), 818-834. e13, 2020 | 379 | 2020 |
Identification of neoantigens for individualized therapeutic cancer vaccines F Lang, B Schrörs, M Löwer, Ö Türeci, U Sahin Nature Reviews Drug Discovery 21 (4), 261-282, 2022 | 272 | 2022 |
Multi-omics characterization of the 4T1 murine mammary gland tumor model B Schrörs, S Boegel, C Albrecht, T Bukur, V Bukur, C Holtsträter, C Ritzel, ... Frontiers in oncology 10, 1195, 2020 | 172 | 2020 |
Melanoma lesions independently acquire T-cell resistance during metastatic latency F Zhao, A Sucker, S Horn, C Heeke, N Bielefeld, B Schrörs, A Bicker, ... Cancer research 76 (15), 4347-4358, 2016 | 78 | 2016 |
Bioinformatics for cancer immunotherapy C Holtsträter, B Schrörs, T Bukur, M Löwer Bioinformatics for Cancer Immunotherapy: Methods and Protocols, 1-9, 2020 | 42 | 2020 |
Mutanome engineered RNA immunotherapy: Towards patient‐centered tumor vaccination M Vormehr, B Schrörs, S Boegel, M Löwer, Ö Türeci, U Sahin Journal of Immunology Research 2015 (1), 595363, 2015 | 42 | 2015 |
HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model B Schrörs, S Lübcke, V Lennerz, M Fatho, A Bicker, C Wölfel, P Derigs, ... Oncotarget 8 (17), 28312, 2017 | 41 | 2017 |
A liposomal RNA vaccine inducing neoantigen-specific CD4+ T cells augments the antitumor activity of local radiotherapy in mice N Salomon, F Vascotto, A Selmi, M Vormehr, J Quinkhardt, T Bukur, ... Oncoimmunology 9 (1), 1771925, 2020 | 40 | 2020 |
Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates B Schrörs, P Riesgo-Ferreiro, P Sorn, R Gudimella, T Bukur, T Rösler, ... PLoS One 16 (9), e0249254, 2021 | 37 | 2021 |
Challenges towards the realization of individualized cancer vaccines Ö Türeci, M Löwer, B Schrörs, M Lang, A Tadmor, U Sahin Nature Biomedical Engineering 2 (8), 566-569, 2018 | 37 | 2018 |
Evolution of melanoma cross-resistance to CD8+ T cells and MAPK inhibition in the course of BRAFi treatment N Pieper, A Zaremba, S Leonardelli, FN Harbers, M Schwamborn, ... Oncoimmunology 7 (8), e1450127, 2018 | 33 | 2018 |
Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens D Weber, J Ibn-Salem, P Sorn, M Suchan, C Holtsträter, U Lahrmann, ... Nature Biotechnology 40 (8), 1276-1284, 2022 | 28 | 2022 |
NeoFox: annotating neoantigen candidates with neoantigen features F Lang, P Riesgo-Ferreiro, M Löwer, U Sahin, B Schrörs Bioinformatics 37 (22), 4246-4247, 2021 | 12 | 2021 |
MC38 colorectal tumor cell lines from two different sources display substantial differences in transcriptome, mutanome and neoantigen expression B Schrörs, BJ Hos, IG Yildiz, M Löwer, F Lang, C Holtsträter, J Becker, ... Frontiers in Immunology 14, 1102282, 2023 | 10 | 2023 |
Vaccination with Designed Neopeptides Induces Intratumoral, Cross-reactive CD4+ T-cell Responses in Glioblastoma J Wang, T Weiss, MC Neidert, NC Toussaint, R Naghavian, ... Clinical Cancer Research 28 (24), 5368-5382, 2022 | 7 | 2022 |
Identification of neoantigens for individualised cancer immunotherapy F Lang, B Schrörs, M Löwer, Ö Türeci, U Sahin Nature reviews. Drug discovery 21 (4), 261, 2022 | 5 | 2022 |
Comprehensive genomic and transcriptomic analysis of three synchronous primary tumours and a recurrence from a head and neck cancer patient L Bresadola, D Weber, C Ritzel, M Löwer, V Bukur, Ö Akilli-Öztürk, ... International journal of molecular sciences 22 (14), 7583, 2021 | 4 | 2021 |
CoVigator—A Knowledge Base for Navigating SARS-CoV-2 Genomic Variants T Bukur, P Riesgo-Ferreiro, P Sorn, R Gudimella, J Hausmann, T Rösler, ... Viruses 15 (6), 1391, 2023 | 3 | 2023 |