Reactions in droplets in microfluidic channels H Song, DL Chen, RF Ismagilov Angewandte chemie international edition 45 (44), 7336-7356, 2006 | 2289 | 2006 |
Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling G Sahay, W Querbes, C Alabi, A Eltoukhy, S Sarkar, C Zurenko, ... Nature biotechnology 31 (7), 653-658, 2013 | 850 | 2013 |
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity KA Whitehead, JR Dorkin, AJ Vegas, PH Chang, O Veiseh, J Matthews, ... Nature communications 5 (1), 4277, 2014 | 531 | 2014 |
Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation D Chen, KT Love, Y Chen, AA Eltoukhy, C Kastrup, G Sahay, A Jeon, ... Journal of the American Chemical Society 134 (16), 6948-6951, 2012 | 517 | 2012 |
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ... Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014 | 506 | 2014 |
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins L Li, D Mustafi, Q Fu, V Tereshko, DL Chen, JD Tice, RF Ismagilov Proceedings of the National Academy of Sciences 103 (51), 19243-19248, 2006 | 311 | 2006 |
The chemistrode: a droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution D Chen, W Du, Y Liu, W Liu, A Kuznetsov, FE Mendez, LH Philipson, ... Proceedings of the National Academy of Sciences 105 (44), 16843-16848, 2008 | 277 | 2008 |
Microgram-scale testing of reaction conditions in solution using nanoliter plugs in microfluidics with detection by MALDI-MS T Hatakeyama, DL Chen, RF Ismagilov Journal of the American Chemical Society 128 (8), 2518-2519, 2006 | 235 | 2006 |
Using microfluidics to observe the effect of mixing on nucleation of protein crystals DL Chen, CJ Gerdts, RF Ismagilov Journal of the American Chemical Society 127 (27), 9672-9673, 2005 | 195 | 2005 |
Slip chip device and methods RF Ismagilov, W Du, L Li, F Shen, KPF Nichols, D Chen, JE Kreutz US Patent 9,415,392, 2016 | 182* | 2016 |
Core-shell hydrogel microcapsules for improved islets encapsulation M Ma, A Chiu, G Sahay, JC Doloff, N Dholakia, R Thakrar, J Cohen, ... Advanced healthcare materials 2 (5), 2013 | 175 | 2013 |
Using three-phase flow of immiscible liquids to prevent coalescence of droplets in microfluidic channels: criteria to identify the third liquid and validation with protein … DL Chen, L Li, S Reyes, DN Adamson, RF Ismagilov Langmuir 23 (4), 2255-2260, 2007 | 165 | 2007 |
Degradable terpolymers with alkyl side chains demonstrate enhanced gene delivery potency and nanoparticle stability AA Eltoukhy, D Chen, CA Alabi, R Langer, DG Anderson Advanced Materials (Deerfield Beach, Fla.) 25 (10), 2013 | 138 | 2013 |
Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening DL Chen, RF Ismagilov Current opinion in chemical biology 10 (3), 226-231, 2006 | 134 | 2006 |
SlipChip for immunoassays in nanoliter volumes W Liu, D Chen, W Du, KP Nichols, RF Ismagilov Analytical chemistry 82 (8), 3276-3282, 2010 | 124 | 2010 |
Amino acid-, peptide-and polypeptide-lipids, isomers, compositions, and uses thereof Y Dong, KT Love, RS Langer, DG Anderson, D Chen, Y Chen, AJ Vegas, ... US Patent 9,512,073, 2016 | 118 | 2016 |
Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo Y Dong, AA Eltoukhy, CA Alabi, OF Khan, O Veiseh, JR Dorkin, ... Advanced healthcare materials 3 (9), 1392, 2014 | 69 | 2014 |
1, 3, 5-triazinane-2, 4, 6-trione derivatives and uses thereof Y Dong, AC Alabi, H Yin, JR Dorkin, D Chen, RS Langer, DG Anderson, ... US Patent 9,315,472, 2016 | 68 | 2016 |
Lipid-modified aminoglycoside derivatives for in vivo siRNA delivery Y Zhang, JM Pelet, DA Heller, Y Dong, D Chen, Z Gu, BJ Joseph, J Wallas, ... Advanced materials (Deerfield Beach, Fla.) 25 (33), 4641, 2013 | 42 | 2013 |
Nucleic acid-mediated intracellular protein delivery by lipid-like nanoparticles AA Eltoukhy, D Chen, O Veiseh, JM Pelet, H Yin, Y Dong, DG Anderson Biomaterials 35 (24), 6454-6461, 2014 | 41 | 2014 |