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Han-Xiang Deng
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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
DR Rosen, T Siddique, D Patterson, DA Figlewicz, P Sapp, A Hentati, ...
Nature 362 (6415), 59-62, 1993
87631993
Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
ME Gurney, H Pu, AY Chiu, MC Dal Canto, CY Polchow, DD Alexander, ...
Science 264 (5166), 1772-1775, 1994
48551994
Amyotrophic lateral Ssclerosis and structural defects in cu, Zn superoxide dismutase
HX Deng, A Hentati, JA Tainer, Z Iqbal, A Cayabyab, WY Hung, ...
Science 261 (5124), 1047-1051, 1993
18871993
Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia
HX Deng, W Chen, ST Hong, KM Boycott, GH Gorrie, N Siddique, Y Yang, ...
Nature 477 (7363), 211-215, 2011
13892011
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
YI Yang, A Hentati, HX Deng, O Dabbagh, T Sasaki, M Hirano, WY Hung, ...
Nature genetics 29 (2), 160-165, 2001
9462001
SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis
F Fecto, J Yan, SP Vemula, E Liu, Y Yang, W Chen, JG Zheng, Y Shi, ...
Archives of neurology 68 (11), 1440-1446, 2011
7692011
Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria
HX Deng, Y Shi, Y Furukawa, H Zhai, R Fu, E Liu, GH Gorrie, MS Khan, ...
Proceedings of the National Academy of Sciences 103 (18), 7142-7147, 2006
5322006
FUS‐immunoreactive inclusions are a common feature in sporadic and non‐SOD1 familial amyotrophic lateral sclerosis
HX Deng, H Zhai, EH Bigio, J Yan, F Fecto, K Ajroud, M Mishra, ...
Annals of neurology 67 (6), 739-748, 2010
4352010
Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement
N Shibata, A Hirano, M Kobayashi, T Siddique, HX Deng, WY Hung, ...
Journal of neuropathology and experimental neurology 55 (4), 481-490, 1996
3691996
FUS pathology defines the majority of tau-and TDP-43-negative frontotemporal lobar degeneration
H Urwin, KA Josephs, JD Rohrer, IR Mackenzie, M Neumann, A Authier, ...
Acta neuropathologica 120, 33-41, 2010
3072010
Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4
HX Deng, CJ Klein, J Yan, Y Shi, Y Wu, F Fecto, HJ Yau, Y Yang, H Zhai, ...
Nature genetics 42 (2), 165-169, 2010
2932010
Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology
JY Kwan, SY Jeong, P Van Gelderen, HX Deng, MM Quezado, ...
PloS one 7 (4), e35241, 2012
2732012
Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice
Y Furukawa, R Fu, HX Deng, T Siddique, TV O'Halloran
Proceedings of the National Academy of Sciences 103 (18), 7148-7153, 2006
2702006
Frameshift and novel mutations in FUS in familial amyotrophic lateral sclerosis and ALS/dementia
J Yan, HX Deng, N Siddique, F Fecto, W Chen, Y Yang, E Liu, ...
Neurology 75 (9), 807-814, 2010
2372010
Genetics of amyotrophic lateral sclerosis
T Siddique, HX Deng
Human molecular genetics 5 (Supplement_1), 1465-1470, 1996
2321996
Identification of TMEM230 mutations in familial Parkinson's disease
HX Deng, Y Shi, Y Yang, KB Ahmeti, N Miller, C Huang, L Cheng, H Zhai, ...
Nature genetics 48 (7), 733-739, 2016
1972016
Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis
J Zhou, J Yi, R Fu, E Liu, T Siddique, E Ríos, HX Deng
Journal of Biological Chemistry 285 (1), 705-712, 2010
1542010
Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse
L Wang, HX Deng, G Grisotti, H Zhai, T Siddique, RP Roos
Human molecular genetics 18 (9), 1642-1651, 2009
1362009
Human α‐tocopherol transfer protein: Gene structure and mutations in familial vitamin E deficiency
A Hentati, HX Deng, WY Hung, M Nayer, MS Ahmed, X He, R Tim, ...
Annals of Neurology: Official Journal of the American Neurological …, 1996
1331996
Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis
R Schüle, T Siddique, HX Deng, Y Yang, S Donkervoort, M Hansson, ...
Journal of lipid research 51 (4), 819-823, 2010
1272010
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