Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo LM Butler, DB Agus, HI Scher, B Higgins, A Rose, C Cordon-Cardo, ... Cancer research 60 (18), 5165-5170, 2000 | 830 | 2000 |
The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin LM Butler, X Zhou, WS Xu, HI Scher, RA Rifkind, PA Marks, VM Richon Proceedings of the National Academy of Sciences 99 (18), 11700-11705, 2002 | 655 | 2002 |
Dual roles of PARP-1 promote cancer growth and progression MJ Schiewer, JF Goodwin, S Han, JC Brenner, MA Augello, JL Dean, ... Cancer discovery 2 (12), 1134-1149, 2012 | 464 | 2012 |
Androgen receptor inhibits estrogen receptor-α activity and is prognostic in breast cancer AA Peters, G Buchanan, C Ricciardelli, T Bianco-Miotto, MM Centenera, ... Cancer research 69 (15), 6131-6140, 2009 | 461 | 2009 |
Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention LM Butler, Y Perone, J Dehairs, LE Lupien, V de Laat, A Talebi, M Loda, ... Advanced drug delivery reviews 159, 245-293, 2020 | 388 | 2020 |
Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer HI Scher, G Buchanan, W Gerald, LM Butler, WD Tilley Endocrine-related cancer 11 (3), 459-476, 2004 | 312 | 2004 |
Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors JL Dean, AK McClendon, TE Hickey, LM Butler, WD Tilley, AK Witkiewicz, ... Cell cycle 11 (14), 2756-2761, 2012 | 248 | 2012 |
Discovery of circulating microRNAs associated with human prostate cancer using a mouse model of disease LA Selth, S Townley, JL Gillis, AM Ochnik, K Murti, RJ Macfarlane, KN Chi, ... International Journal of Cancer 131 (3), 652-661, 2012 | 243 | 2012 |
Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer G Zadra, CF Ribeiro, P Chetta, Y Ho, S Cacciatore, X Gao, S Syamala, ... Proceedings of the National Academy of Sciences 116 (2), 631-640, 2019 | 234 | 2019 |
Maximizing the therapeutic potential of HSP90 inhibitors LM Butler, R Ferraldeschi, HK Armstrong, MM Centenera, P Workman Molecular cancer research 13 (11), 1445-1451, 2015 | 222 | 2015 |
The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid DC Coffey, MC Kutko, RD Glick, LM Butler, G Heller, RA Rifkind, PA Marks, ... Cancer research 61 (9), 3591-3594, 2001 | 206 | 2001 |
Tumour fatty acid metabolism in the context of therapy resistance and obesity AJ Hoy, SR Nagarajan, LM Butler Nature Reviews Cancer 21 (12), 753-766, 2021 | 205 | 2021 |
Cancer-associated fibroblasts—heroes or villains? KA Gieniec, LM Butler, DL Worthley, SL Woods British journal of cancer 121 (4), 293-302, 2019 | 204 | 2019 |
Minireview: the contribution of different androgen receptor domains to receptor dimerization and signaling MM Centenera, JM Harris, WD Tilley, LM Butler Molecular endocrinology 22 (11), 2373-2382, 2008 | 195 | 2008 |
Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development T Bianco-Miotto, K Chiam, G Buchanan, S Jindal, TK Day, M Thomas, ... Cancer epidemiology, biomarkers & prévention 19 (10), 2611-2622, 2010 | 192 | 2010 |
Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase LM Butler, Y Webb, DB Agus, B Higgins, TR Tolentino, MC Kutko, ... Clinical cancer research 7 (4), 962-970, 2001 | 177 | 2001 |
Peptidomimetic targeting of critical androgen receptor–coregulator interactions in prostate cancer P Ravindranathan, TK Lee, L Yang, MM Centenera, L Butler, WD Tilley, ... Nature communications 4 (1), 1923, 2013 | 163 | 2013 |
Ex vivo culture of human prostate tissue and drug development MM Centenera, GV Raj, KE Knudsen, WD Tilley, LM Butler Nature Reviews Urology 10 (8), 483-487, 2013 | 148 | 2013 |
Circulating microRNAs predict biochemical recurrence in prostate cancer patients LA Selth, SL Townley, AG Bert, PD Stricker, PD Sutherland, LG Horvath, ... British journal of cancer 109 (3), 641-650, 2013 | 143 | 2013 |
The diversity and breadth of cancer cell fatty acid metabolism SR Nagarajan, LM Butler, AJ Hoy Cancer & Metabolism 9 (1), 2, 2021 | 127 | 2021 |