Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections B Ogunjimi, SY Zhang, KB Sørensen, KA Skipper, M Carter-Timofte, ... The Journal of clinical investigation 127 (9), 3543-3556, 2017 | 128 | 2017 |
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis FG Lafaille, O Harschnitz, YS Lee, P Zhang, ML Hasek, G Kerner, Y Itan, ... Nature medicine 25 (12), 1873-1884, 2019 | 101 | 2019 |
Mutations in RNA Polymerase III genes and defective DNA sensing in adults with varicella-zoster virus CNS infection ME Carter-Timofte, AF Hansen, M Christiansen, SR Paludan, ... Genes & Immunity 20 (3), 214-223, 2019 | 60 | 2019 |
Deciphering the role of host genetics in susceptibility to severe COVID-19 ME Carter-Timofte, SE Jørgensen, MR Freytag, MM Thomsen, ... Frontiers in immunology 11, 1606, 2020 | 56 | 2020 |
Varicella-zoster virus CNS vasculitis and RNA polymerase III gene mutation in identical twins ME Carter-Timofte, AF Hansen, M Mardahl, S Fribourg, F Rapaport, ... Neurology: Neuroimmunology & Neuroinflammation 5 (6), e500, 2018 | 49 | 2018 |
RNA polymerase III as a gatekeeper to prevent severe VZV infections ME Carter-Timofte, SR Paludan, TH Mogensen Trends in Molecular Medicine 24 (10), 904-915, 2018 | 41 | 2018 |
Regulation of innate immunity by Nrf2 D van der Horst, ME Carter-Timofte, J van Grevenynghe, N Laguette, ... Current Opinion in Immunology 78, 102247, 2022 | 36 | 2022 |
Antiviral potential of the antimicrobial drug atovaquone against SARS-CoV-2 and emerging variants of concern ME Carter-Timofte, R Arulanandam, N Kurmasheva, K Fu, G Laroche, ... ACS infectious diseases 7 (11), 3034-3051, 2021 | 23 | 2021 |
Genetic variants and immune responses in a cohort of patients with varicella zoster virus encephalitis MM Thomsen, T Tyrberg, K Skaalum, M Carter-Timofte, MR Freytag, ... The Journal of infectious diseases 224 (12), 2122-2132, 2021 | 10 | 2021 |
VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney MM Rinschen, JL Harder, ME Carter-Timofte, L Zanon Rodriguez, ... Science signaling 15 (762), eabo7940, 2022 | 8 | 2022 |
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen Z Taha, R Arulanandam, G Maznyi, E Godbout, ME Carter-Timofte, ... Molecular Therapy 30 (9), 2998-3016, 2022 | 7 | 2022 |
Impaired STING Activation Due to a Variant in the E3 Ubiquitin Ligase AMFR in a Patient with Severe VZV Infection and Hemophagocytic Lymphohistiocytosis MM Thomsen, MK Skouboe, M Møhlenberg, J Zhao, K de Keukeleere, ... Journal of Clinical Immunology 44 (2), 1-19, 2024 | 1 | 2024 |
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways N Kurmasheva, A Said, B Wong, P Kinderman, X Han, AHF Rahimic, ... Nature Communications 15 (1), 4096, 2024 | | 2024 |
Itaconate enhances oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways N Kurmasheva, A Said, B Wong, A Kress, Z Liu, C Wang, M Carter-Timofte, ... | | 2023 |
Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development S Boulton, MJF Crupi, S Singh, ME Carter-Timofte, T Azad, BC Organ, ... Journal of Biological Chemistry 299 (6), 2023 | | 2023 |