Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD S Boeynaems, E Bogaert, E Michiels, I Gijselinck, A Sieben, A Jovičić, ... Scientific reports 6 (1), 20877, 2016 | 279 | 2016 |
Hsp90 mediates membrane deformation and exosome release E Lauwers, YC Wang, R Gallardo, R Van der Kant, E Michiels, J Swerts, ... Molecular cell 71 (5), 689-702. e9, 2018 | 140 | 2018 |
A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation Y Dorone, S Boeynaems, E Flores, B Jin, S Hateley, F Bossi, E Lazarus, ... Cell 184 (16), 4284-4298. e27, 2021 | 132 | 2021 |
Aggregating sequences that occur in many proteins constitute weak spots of bacterial proteostasis L Khodaparast, L Khodaparast, R Gallardo, NN Louros, E Michiels, ... Nature communications 9 (1), 866, 2018 | 61 | 2018 |
Thermodynamic and evolutionary coupling between the native and amyloid state of globular proteins T Langenberg, R Gallardo, R van der Kant, N Louros, E Michiels, ... Cell reports 31 (2), 2020 | 38 | 2020 |
Reverse engineering synthetic antiviral amyloids E Michiels, K Roose, R Gallardo, L Khodaparast, L Khodaparast, ... Nature communications 11 (1), 2832, 2020 | 36 | 2020 |
Autonomous aggregation suppression by acidic residues explains why chaperones favour basic residues B Houben, E Michiels, M Ramakers, K Konstantoulea, N Louros, ... The EMBO journal 39 (11), e102864, 2020 | 32 | 2020 |
Heterotypic Amyloid β interactions facilitate amyloid assembly and modify amyloid structure K Konstantoulea, P Guerreiro, M Ramakers, N Louros, LD Aubrey, ... The EMBO journal 41 (2), e108591, 2022 | 26 | 2022 |
Mechanisms and therapeutic potential of interactions between human amyloids and viruses E Michiels, F Rousseau, J Schymkowitz Cellular and Molecular Life Sciences 78 (6), 2485-2501, 2021 | 24 | 2021 |
Preparation of amorphous solid dispersions by cryomilling: chemical and physical concerns related to active pharmaceutical ingredients and carriers T Pas, A Bergonzi, E Michiels, F Rousseau, J Schymkowitz, R Koekoekx, ... Molecular Pharmaceutics 17 (3), 1001-1013, 2020 | 24 | 2020 |
Liquid–liquid phase separation enhances TDP-43 LCD aggregation but delays seeded aggregation D Pakravan, E Michiels, A Bratek-Skicki, M De Decker, J Van Lindt, ... Biomolecules 11 (4), 548, 2021 | 20 | 2021 |
In silico prediction of in vitro protein liquid–liquid phase separation experiments outcomes with multi-head neural attention D Raimondi, G Orlando, E Michiels, D Pakravan, A Bratek-Skicki, ... Bioinformatics 37 (20), 3473-3479, 2021 | 16 | 2021 |
Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers N Louros, M Ramakers, E Michiels, K Konstantoulea, C Morelli, T Garcia, ... Nature communications 13 (1), 1351, 2022 | 13 | 2022 |
Entropic bristles tune the seeding efficiency of prion-nucleating fragments E Michiels, S Liu, R Gallardo, N Louros, M Mathelie-Guinlet, Y Dufrêne, ... Cell reports 30 (8), 2834-2845. e3, 2020 | 11 | 2020 |
Hydration-dependent phase separation of a prion-like protein regulates seed germination during water stress Y Dorone, S Boeynaems, B Jin, F Bossi, E Flores, E Lazarus, E Michiels, ... BioRXiV, 2020.08. 07.242172, 2020 | 8 | 2020 |
A workflow for streamlined acquisition and correlation of serial regions of interest in array tomography S Gabarre, F Vernaillen, P Baatsen, K Vints, C Cawthorne, S Boeynaems, ... BMC biology 19, 1-15, 2021 | 6 | 2021 |
The tumor suppressor protein PTEN undergoes amyloid-like aggregation in tumor cells F Claes, E Maritschnegg, G De Baets, A Siekierska, MS Rubio, ... BioRxiv, 2020.11. 30.402115, 2020 | 6 | 2020 |
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V F Claes, S Rudyak, AS Laird, N Louros, J Beerten, M Debulpaep, ... Protein Engineering, Design and Selection 32 (10), 443-457, 2019 | 6 | 2019 |
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD. Sci Rep. 2016; 6: 20877 S Boeynaems, E Bogaert, E Michiels, I Gijselinck, A Sieben, A Jovičić, ... | 3 | |
Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding L Khodaparast, L Khodaparast, G Wu, E Michiels, R Gallardo, B Houben, ... Nature Communications 14 (1), 5571, 2023 | | 2023 |