HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer CJ David, M Chen, M Assanah, P Canoll, JL Manley Nature 463 (7279), 364-368, 2010 | 1277 | 2010 |
Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged CJ David, JL Manley Genes & development 24 (21), 2343-2364, 2010 | 962 | 2010 |
Contextual determinants of TGFβ action in development, immunity and cancer CJ David, J Massagué Nature reviews Molecular cell biology 19 (7), 419-435, 2018 | 771 | 2018 |
TGF-β tumor suppression through a lethal EMT CJ David, YH Huang, M Chen, J Su, Y Zou, N Bardeesy, ... Cell 164 (5), 1015-1030, 2016 | 618 | 2016 |
TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1 J Su, SM Morgani, CJ David, Q Wang, EE Er, YH Huang, H Basnet, Y Zou, ... Nature 577 (7791), 566-571, 2020 | 380 | 2020 |
hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing T Kashima, N Rao, CJ David, JL Manley Human molecular genetics 16 (24), 3149-3159, 2007 | 235 | 2007 |
The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65–Prp19 complex CJ David, AR Boyne, SR Millhouse, JL Manley Genes & development 25 (9), 972-983, 2011 | 226 | 2011 |
Overexpression of AtCPS and AtKS in Arabidopsis Confers Increased ent-Kaurene Production But No Increase in Bioactive Gibberellins CM Fleet, S Yamaguchi, A Hanada, H Kawaide, CJ David, Y Kamiya, ... Plant physiology 132 (2), 830-839, 2003 | 169 | 2003 |
Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins M Chen, CJ David, JL Manley Nature structural & molecular biology 19 (3), 346-354, 2012 | 131 | 2012 |
Mutant Kras co-opts a proto-oncogenic enhancer network in inflammation-induced metaplastic progenitor cells to initiate pancreatic cancer Y Li, Y He, J Peng, Z Su, Z Li, B Zhang, J Ma, M Zhuo, D Zou, X Liu, X Liu, ... Nature Cancer 2 (1), 49-65, 2021 | 74 | 2021 |
The search for alternative splicing regulators: new approaches offer a path to a splicing code CJ David, JL Manley Genes & development 22 (3), 279-285, 2008 | 74 | 2008 |
ID1 mediates escape from TGFβ tumor suppression in pancreatic cancer YH Huang, J Hu, F Chen, N Lecomte, H Basnet, CJ David, MD Witkin, ... Cancer discovery 10 (1), 142-157, 2020 | 69 | 2020 |
A cleavable affinity biotinylating agent reveals a retinoid binding role for RPE65 WJ Jahng, C David, N Nesnas, K Nakanishi, RR Rando Biochemistry 42 (20), 6159-6168, 2003 | 69 | 2003 |
Optimization of a total acid hydrolysis based protocol for the quantification of carbohydrate in macroalgae E Kostas, W Stuart, W Daniel, C David Journal of Algal Biomass Utilization 7 (1), 21-36, 2016 | 37 | 2016 |
The RNA polymerase C-terminal domain: a new role in spliceosome assembly CJ David, JL Manley Transcription 2 (5), 221-225, 2011 | 35 | 2011 |
The PAF1 complex promotes 3′ processing of pervasive transcripts X Liu, Z Guo, J Han, B Peng, B Zhang, H Li, X Hu, CJ David, M Chen Cell reports 38 (11), 2022 | 25 | 2022 |
Tumor-derived Jagged1 promotes cancer progression through immune evasion J Meng, Y Jiang, S Zhao, Y Tao, T Zhang, X Wang, Y Zhang, K Sun, ... Cell Reports 38 (10), 2022 | 23 | 2022 |
Tumor metabolism: hnRNP proteins get in on the act M Chen, CJ David, JL Manley Cell Cycle 9 (10), 1863-1864, 2010 | 17 | 2010 |
Publisher Correction: Contextual determinants of TGFβ action in development, immunity and cancer. CJ David, J Massagué Nature reviews. Molecular Cell Biology 19 (7), 479-479, 2018 | 14 | 2018 |
The effect of gibberellins (GA3 and GA4+ 7) and ethanol on seed germination of Rosa eglanteria and Rosa glauca C David Journal of Plant Growth Regulation 41, 1-10, 2010 | 8 | 2010 |