A special population of regulatory T cells potentiates muscle repair D Burzyn, W Kuswanto, D Kolodin, JL Shadrach, M Cerletti, Y Jang, ... Cell 155 (6), 1282-1295, 2013 | 1201 | 2013 |
Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses N Joller, E Lozano, PR Burkett, B Patel, S Xiao, C Zhu, J Xia, TG Tan, ... Immunity 40 (4), 569-581, 2014 | 919 | 2014 |
Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells E Sefik, N Geva-Zatorsky, S Oh, L Konnikova, D Zemmour, AM McGuire, ... Science 349 (6251), 993-997, 2015 | 868 | 2015 |
Mining the human gut microbiota for immunomodulatory organisms N Geva-Zatorsky, E Sefik, L Kua, L Pasman, TG Tan, A Ortiz-Lopez, ... Cell 168 (5), 928-943. e11, 2017 | 703 | 2017 |
Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice MA Kriegel, E Sefik, JA Hill, HJ Wu, C Benoist, D Mathis Proceedings of the National Academy of Sciences 108 (28), 11548-11553, 2011 | 467 | 2011 |
Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice TG Tan, E Sefik, N Geva-Zatorsky, L Kua, D Naskar, F Teng, L Pasman, ... Proceedings of the National Academy of Sciences 113 (50), E8141-E8150, 2016 | 415 | 2016 |
Inflammasome activation in infected macrophages drives COVID-19 pathology E Sefik, R Qu, C Junqueira, E Kaffe, H Mirza, J Zhao, JR Brewer, A Han, ... Nature 606 (7914), 585-593, 2022 | 366 | 2022 |
m6A mRNA methylation sustains Treg suppressive functions J Tong, G Cao, T Zhang, E Sefik, MC Amezcua Vesely, JP Broughton, ... Cell Research 28 (2), 253-256, 2018 | 286 | 2018 |
Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival TW Hand, W Cui, YW Jung, E Sefik, NS Joshi, A Chandele, Y Liu, ... Proceedings of the National Academy of Sciences 107 (38), 16601-16606, 2010 | 253 | 2010 |
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut AM Morton, E Sefik, R Upadhyay, R Weissleder, C Benoist, D Mathis Proceedings of the National Academy of Sciences 111 (18), 6696-6701, 2014 | 180 | 2014 |
Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity A Jarret, R Jackson, C Duizer, ME Healy, J Zhao, JM Rone, P Bielecki, ... Cell 180 (1), 50-63. e12, 2020 | 167 | 2020 |
mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence SS Hwang, J Lim, Z Yu, P Kong, E Sefik, H Xu, CCD Harman, LK Kim, ... Science 367 (6483), 1255-1260, 2020 | 148 | 2020 |
Control of peripheral tolerance by regulatory T cell–intrinsic Notch signaling LM Charbonnier, S Wang, P Georgiev, E Sefik, TA Chatila Nature immunology 16 (11), 1162-1173, 2015 | 144 | 2015 |
An immunologic mode of multigenerational transmission governs a gut Treg setpoint D Ramanan, E Sefik, S Galván-Peña, M Wu, L Yang, Z Yang, A Kostic, ... Cell 181 (6), 1276-1290. e13, 2020 | 132 | 2020 |
Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses JS Low, Y Farsakoglu, MC Amezcua Vesely, E Sefik, JB Kelly, ... Journal of Experimental Medicine 217 (8), 2020 | 107 | 2020 |
Detection of differentially abundant cell subpopulations in scRNA-seq data J Zhao, A Jaffe, H Li, O Lindenbaum, E Sefik, R Jackson, X Cheng, ... Proceedings of the National Academy of Sciences 118 (22), e2100293118, 2021 | 97 | 2021 |
A humanized mouse model of chronic COVID-19 E Sefik, B Israelow, H Mirza, J Zhao, R Qu, E Kaffe, E Song, S Halene, ... Nature biotechnology 40 (6), 906-920, 2022 | 84 | 2022 |
RNA m6A demethylase ALKBH5 regulates the development of γδ T cells C Ding, H Xu, Z Yu, M Roulis, R Qu, J Zhou, J Oh, J Crawford, Y Gao, ... Proceedings of the National Academy of Sciences 119 (33), e2203318119, 2022 | 30 | 2022 |
Regulatory T cells in the face of the intestinal microbiota D Ramanan, A Pratama, Y Zhu, O Venezia, M Sassone-Corsi, ... Nature Reviews Immunology 23 (11), 749-762, 2023 | 25 | 2023 |
Human neutrophil development and functionality are enabled in a humanized mouse model Y Zheng, E Sefik, J Astle, K Karatepe, HH Öz, AG Solis, R Jackson, ... Proceedings of the National Academy of Sciences 119 (43), e2121077119, 2022 | 19 | 2022 |