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Paul Lehner
Paul Lehner
Professor of Immunobiology Cambridge University
在 cam.ac.uk 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP
B Sadasivan, PJ Lehner, B Ortmann, T Spies, P Cresswell
Immunity 5 (2), 103-114, 1996
9351996
CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity
ML Burr, CE Sparbier, YC Chan, JC Williamson, K Woods, PA Beavis, ...
Nature 549 (7670), 101-105, 2017
7522017
A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes
B Ortmann, J Copeman, PJ Lehner, B Sadasivan, JA Herberg, ...
Science 277 (5330), 1306-1309, 1997
6801997
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2
DA Collier, IATM Ferreira, P Kotagiri, RP Datir, EY Lim, E Touizer, B Meng, ...
Nature 596 (7872), 417-422, 2021
6362021
Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission
L Rivett, S Sridhar, D Sparkes, M Routledge, NK Jones, S Forrest, ...
elife 9, e58728, 2020
5982020
Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers
MB Reeves, PA MacAry, PJ Lehner, JGP Sissons, JH Sinclair
Proceedings of the National Academy of Sciences 102 (11), 4140-4145, 2005
4832005
Quantitative temporal viromics: an approach to investigate host-pathogen interaction
MP Weekes, P Tomasec, EL Huttlin, CA Fielding, D Nusinow, RJ Stanton, ...
Cell 157 (6), 1460-1472, 2014
4792014
NOTCH1 mediates a switch between two distinct secretomes during senescence
M Hoare, Y Ito, TW Kang, MP Weekes, NJ Matheson, DA Patten, S Shetty, ...
Nature cell biology 18 (9), 979-992, 2016
4512016
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer
ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ...
Cancer cell 36 (4), 385-401. e8, 2019
4442019
Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts
RA Floto, MR Clatworthy, KR Heilbronn, DR Rosner, PA MacAry, ...
Nature medicine 11 (10), 1056-1058, 2005
3902005
Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line. 220
PJ Lehner, MJ Surman, P Cresswell
Immunity 8 (2), 221-231, 1998
3731998
The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation
PJ Lehner, JT Karttunen, GWG Wilkinson, P Cresswell
Proceedings of the National Academy of Sciences 94 (13), 6904-6909, 1997
3601997
Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules
LM Duncan, S Piper, RB Dodd, MK Saville, CM Sanderson, JP Luzio, ...
The EMBO journal 25 (8), 1635-1645, 2006
3452006
CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokines
Y Wang, CG Kelly, JT Karttunen, T Whittall, PJ Lehner, L Duncan, ...
Immunity 15 (6), 971-983, 2001
3432001
Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment.
PJ Lehner, EC Wang, PA Moss, S Williams, K Platt, SM Friedman, JI Bell, ...
The Journal of experimental medicine 181 (1), 79-91, 1995
3221995
Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells
IA Tchasovnikarova, RT Timms, NJ Matheson, K Wals, R Antrobus, ...
Science 348 (6242), 1481-1485, 2015
3082015
Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
L Bergamaschi, F Mescia, L Turner, AL Hanson, P Kotagiri, BJ Dunmore, ...
Immunity 54 (6), 1257-1275. e8, 2021
2822021
Inhibition of MHC class I-restricted antigen presentation by γ2-herpesviruses
PG Stevenson, S Efstathiou, PC Doherty, PJ Lehner
Proceedings of the National Academy of Sciences 97 (15), 8455-8460, 2000
2622000
The human cytomegalovirus gene product US6 inhibits ATP binding by TAP
EW Hewitt, SS Gupta, PJ Lehner
The EMBO journal, 2001
2592001
Viral avoidance and exploitation of the ubiquitin system
F Randow, PJ Lehner
Nature cell biology 11 (5), 527-534, 2009
2492009
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