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Juan Fafian Labora
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Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein IFITM3
M Borghesan, J Fafián-Labora, O Eleftheriadou, P Carpintero-Fernández, ...
Cell Reports 27 (13), 3956-3971. e6, 2019
2302019
Classical and nonclassical intercellular communication in senescence and ageing
JA Fafián-Labora, A O’Loghlen
Trends in cell biology 30 (8), 628-639, 2020
1472020
Small extracellular vesicles have GST activity and ameliorate senescence-related tissue damage
JA Fafián-Labora, JA Rodríguez-Navarro, A O’Loghlen
Cell metabolism 32 (1), 71-86. e5, 2020
1282020
Effect of age on pro-inflammatory miRNAs contained in mesenchymal stem cell-derived extracellular vesicles
J Fafián-Labora, I Lesende-Rodríguez, P Fernández-Pernas, ...
Scientific reports 7 (1), 43923, 2017
862017
Influence of age on rat bone-marrow mesenchymal stem cells potential
J Fafián-Labora, P Fernández-Pernas, I Fuentes, J De Toro, N Oreiro, ...
Scientific reports 5 (1), 16765, 2015
812015
Effect of aging on behaviour of mesenchymal stem cells
JA Fafián-Labora, M Morente-López, MC Arufe
World Journal of Stem Cells 11 (6), 337, 2019
782019
FASN activity is important for the initial stages of the induction of senescence
J Fafián-Labora, P Carpintero-Fernández, SJD Jordan, T Shikh-Bahaei, ...
Cell death & disease 10 (4), 318, 2019
682019
Technical advances to study extracellular vesicles
P Carpintero-Fernández, J Fafián-Labora, A O'Loghlen
Frontiers in molecular biosciences 4, 79, 2017
542017
iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis
J Mateos, A Landeira-Abia, JA Fafián-Labora, P Fernández-Pernas, ...
Stem cell research & therapy 6, 1-17, 2015
432015
Influence of mesenchymal stem cell-derived extracellular vesicles in vitro and their role in ageing
J Fafián-Labora, M Morente-López, MJ Sánchez-Dopico, OJ Arntz, ...
Stem Cell Research & Therapy 11, 1-12, 2020
382020
NF‐κB/IKK activation by small extracellular vesicles within the SASP
JA Fafián‐Labora, A O’Loghlen
Aging cell 20 (7), e13426, 2021
322021
Therapeutic potential for regulation of the nuclear factor kappa-B transcription factor p65 to prevent cellular senescence and activation of pro-inflammatory in mesenchymal …
R Mato-Basalo, M Morente-López, OJ Arntz, FAJ van de Loo, ...
International journal of molecular sciences 22 (7), 3367, 2021
292021
Biodistribution and immunogenicity of allogeneic mesenchymal stem cells in a rat model of intraarticular chondrocyte xenotransplantation
M Marquina, JA Collado, M Pérez-Cruz, P Fernández-Pernas, ...
Frontiers in Immunology 8, 1465, 2017
192017
Next-Generation Sequencing and Quantitative Proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature aging
J Mateos, J Fafian-Labora, M Morente-Lopez, I Lesende-Rodriguez, ...
PLoS One 13 (10), e0205878, 2018
182018
3, 3′, 5‐triiodo‐l‐thyronine Increases in vitro chondrogenesis of mesenchymal stem cells from human umbilical cord stroma through SRC2
P Fernández‐Pernas, J Fafián‐Labora, I Lesende‐Rodriguez, J Mateos, ...
Journal of cellular biochemistry 117 (9), 2097-2108, 2016
172016
Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence
P Carpintero-Fernández, M Borghesan, O Eleftheriadou, B Pan-Castillo, ...
Cell death & disease 13 (2), 163, 2022
142022
Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA
M Morente-López, R Mato-Basalo, S Lucio-Gallego, L Silva-Fernández, ...
Cellular and Molecular Life Sciences 79 (11), 557, 2022
102022
Proteomic applications in the study of human mesenchymal stem cells
J Mateos, P Fernández Pernas, J Fafián Labora, F Blanco, MDC Arufe
Proteomes 2 (1), 53-71, 2014
102014
Study of Ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells
C Alarcón-Veleiro, R Mato-Basalo, S Lucio-Gallego, A Vidal-Pampín, ...
Antioxidants 12 (1), 183, 2023
82023
High-throughput screen detects calcium signaling dysfunction in hutchinson-gilford progeria syndrome
JA Fafián-Labora, M Morente-López, FJ de Toro, MC Arufe
International journal of molecular sciences 22 (14), 7327, 2021
62021
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