SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles CB Plescia, EA David, D Patra, R Sengupta, S Amiar, Y Su, RV Stahelin Journal of Biological Chemistry, 2020 | 91 | 2020 |
Synthesis and biological evaluation of the first triple inhibitors of human topoisomerase 1, tyrosyl–DNA phosphodiesterase 1 (Tdp1), and tyrosyl–DNA phosphodiesterase 2 (Tdp2) P Wang, MSA Elsayed, CB Plescia, A Ravji, CE Redon, E Kiselev, ... Journal of medicinal chemistry 60 (8), 3275-3288, 2017 | 59 | 2017 |
Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons DE Beck, W Lv, M Abdelmalak, CB Plescia, K Agama, C Marchand, ... Bioorganic & medicinal chemistry 24 (7), 1469-1479, 2016 | 40 | 2016 |
Synthesis and structure-activity relationship of furoquinolinediones as inhibitors of Tyrosyl-DNA phosphodiesterase 2 (TDP2) LM Yu, Z Hu, Y Chen, A Ravji, S Lopez, CB Plescia, Q Yu, H Yang, ... European journal of medicinal chemistry 151, 777-796, 2018 | 23 | 2018 |
A pyrene-based two-photon excitable fluorescent probe to visualize nuclei in live cells CS Abeywickrama, KJ Wijesinghe, CB Plescia, LS Fisher, T Goodson, ... Photochemical & Photobiological Sciences 19, 1152-1159, 2020 | 21 | 2020 |
Structural effect on the cellular selectivity of an NIR-emitting cyanine probe: from lysosome to simultaneous nucleus and mitochondria selectivity with potential for monitoring … CS Abeywickrama, KA Bertman, CB Plescia, RV Stahelin, Y Pang ACS Applied Bio Materials 2 (11), 5174-5181, 2019 | 18 | 2019 |
The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity and contributes to membrane binding SK Ravala, JB Hopkins, CB Plescia, SR Allgood, MA Kane, JN Cash, ... Journal of Biological Chemistry 295 (36), 12635-12647, 2020 | 15 | 2020 |
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding ML Husby, S Amiar, LI Prugar, EA David, CB Plescia, KE Huie, ... EMBO reports 23 (11), e51709, 2022 | 14 | 2022 |
Evaluation of phenol-substituted diphyllin derivatives as selective antagonists for ebola virus entry CB Plescia, AR Lindstrom, MV Quintero, P Keiser, M Anantpadma, ... ACS infectious diseases 8 (5), 942-957, 2022 | 10 | 2022 |
Characterization of the relationship between the chaperone and lipid-binding functions of the 70-kDa heat-shock protein, HspA1A L Smulders, AJ Daniels, CB Plescia, D Berger, RV Stahelin, N Nikolaidis International journal of molecular sciences 21 (17), 5995, 2020 | 9 | 2020 |
The Ebola virus matrix protein clusters phosphatidylserine, a critical step in viral budding ML Husby, S Amiar, LI Prugar, EA David, CB Plescia, KE Huie, ... BioRxiv, 2021.06. 08.447555, 2021 | 4 | 2021 |
The SARS-CoV-2 nucleoprotein associates with anionic lipid membranes M Dutta, Y Su, CB Plescia, GA Voth, RV Stahelin Journal of Biological Chemistry, 107456, 2024 | 2 | 2024 |
Evaluation of potency and metabolic stability of diphyllin-derived Vacuolar-ATPase inhibitors LM Sanford, P Keiser, N Fujii, H Woods, C Zhang, Z Xu, NS Mahajani, ... European Journal of Medicinal Chemistry 275, 116537, 2024 | | 2024 |
Modeling the Molecular Biology of Infection & Anti-Viral Activity of Small Molecules for Ebola Virus & SARS-CoV-2 using Virus-Like Particles CB Plescia Purdue University Graduate School, 2022 | | 2022 |