Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos Y Niu, B Shen, Y Cui, Y Chen, J Wang, L Wang, Y Kang, X Zhao, W Si, ... Cell 156 (4), 836-843, 2014 | 1347 | 2014 |
Genome of the Chinese tree shrew Y Fan, ZY Huang, CC Cao, CS Chen, YX Chen, DD Fan, J He, HL Hou, ... Nature communications 4 (1), 1426, 2013 | 413 | 2013 |
A developmental landscape of 3D-cultured human pre-gastrulation embryos L Xiang, Y Yin, Y Zheng, Y Ma, Y Li, Z Zhao, J Guo, Z Ai, Y Niu, K Duan, ... Nature 577 (7791), 537-542, 2020 | 339 | 2020 |
Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9 Y Chen, Y Zheng, Y Kang, W Yang, Y Niu, X Guo, Z Tu, C Si, H Wang, ... Human molecular genetics 24 (13), 3764-3774, 2015 | 290 | 2015 |
TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys H Liu, Y Chen, Y Niu, K Zhang, Y Kang, W Ge, X Liu, E Zhao, C Wang, ... Cell stem cell 14 (3), 323-328, 2014 | 236 | 2014 |
Modeling Rett syndrome using TALEN-edited MECP2 mutant cynomolgus monkeys Y Chen, J Yu, Y Niu, D Qin, H Liu, G Li, Y Hu, J Wang, Y Lu, Y Kang, ... Cell 169 (5), 945-955. e10, 2017 | 201 | 2017 |
Dissecting primate early post-implantation development using long-term in vitro embryo culture Y Niu, N Sun, C Li, Y Lei, Z Huang, J Wu, C Si, X Dai, C Liu, J Wei, L Liu, ... Science 366 (6467), eaaw5754, 2019 | 174 | 2019 |
Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo T Tan, J Wu, C Si, S Dai, Y Zhang, N Sun, E Zhang, H Shao, W Si, P Yang, ... Cell 184 (8), 2020-2032. e14, 2021 | 141 | 2021 |
Generation and characterization of rabbit embryonic stem cells S Wang, X Tang, Y Niu, H Chen, B Li, T Li, X Zhang, Z Hu, Q Zhou, W Ji Stem Cells 25 (2), 481-489, 2007 | 133 | 2007 |
Resurrection of endogenous retroviruses during aging reinforces senescence X Liu, Z Liu, Z Wu, J Ren, Y Fan, L Sun, G Cao, Y Niu, B Zhang, Q Ji, ... Cell 186 (2), 287-304. e26, 2023 | 129 | 2023 |
Generation of cynomolgus monkey chimeric fetuses using embryonic stem cells Y Chen, Y Niu, Y Li, Z Ai, Y Kang, H Shi, Z Xiang, Z Yang, T Tan, W Si, ... Cell Stem Cell 17 (1), 116-124, 2015 | 128 | 2015 |
One-step generation of p53 gene biallelic mutant Cynomolgus monkey via the CRISPR/Cas system H Wan, C Feng, F Teng, S Yang, B Hu, Y Niu, AP Xiang, W Fang, W Ji, ... Cell research 25 (2), 258-261, 2015 | 121 | 2015 |
Transgenic rhesus monkeys produced by gene transfer into early-cleavage–stage embryos using a simian immunodeficiency virus-based vector Y Niu, Y Yu, A Bernat, S Yang, X He, X Guo, D Chen, Y Chen, S Ji, W Si, ... Proceedings of the National Academy of Sciences 107 (41), 17663-17667, 2010 | 105 | 2010 |
CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH Y Kang, B Zheng, B Shen, Y Chen, L Wang, J Wang, Y Niu, Y Cui, J Zhou, ... Human molecular genetics 24 (25), 7255-7264, 2015 | 101 | 2015 |
Early Parkinson's disease symptoms in α-synuclein transgenic monkeys Y Niu, X Guo, Y Chen, CE Wang, J Gao, W Yang, Y Kang, W Si, H Wang, ... Human molecular genetics 24 (8), 2308-2317, 2015 | 98 | 2015 |
Epigenetic marks in cloned rhesus monkey embryos: comparison with counterparts produced in vitro J Yang, S Yang, N Beaujean, Y Niu, X He, Y Xie, X Tang, L Wang, Q Zhou, ... Biology of reproduction 76 (1), 36-42, 2007 | 93 | 2007 |
Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development L Shi, X Luo, J Jiang, Y Chen, C Liu, T Hu, M Li, Q Lin, Y Li, J Huang, ... National Science Review 6 (3), 480-493, 2019 | 76 | 2019 |
Amnion signals are essential for mesoderm formation in primates R Yang, A Goedel, Y Kang, C Si, C Chu, Y Zheng, Z Chen, PJ Gruber, ... Nature communications 12 (1), 5126, 2021 | 71 | 2021 |
Dissecting signaling pathways that govern self-renewal of rabbit embryonic stem cells S Wang, Y Shen, X Yuan, K Chen, X Guo, Y Chen, Y Niu, J Li, RH Xu, ... Journal of Biological Chemistry 283 (51), 35929-35940, 2008 | 65 | 2008 |
Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing F Wang, W Zhang, Q Yang, Y Kang, Y Fan, J Wei, Z Liu, S Dai, H Li, Z Li, ... Protein & cell 11 (11), 809-824, 2020 | 60 | 2020 |