| Effects of tobacco smoking and nicotine on cancer treatment WP Petros, IR Younis, JN Ford, SA Weed Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 32 (10 …, 2012 | 91 | 2012 |
| Influence of pH on the dissolution of folic acid supplements IR Younis, MK Stamatakis, PS Callery, PJ Meyer-Stout International journal of pharmaceutics 367 (1-2), 97-102, 2009 | 63 | 2009 |
| Methadone metabolism and drug-drug interactions: in vitro and in vivo literature review DA Volpe, Y Xu, CG Sahajwalla, IR Younis, V Patel Journal of Pharmaceutical Sciences 107 (12), 2983-2991, 2018 | 56 | 2018 |
| Enterohepatic recirculation model of irinotecan (CPT-11) and metabolite pharmacokinetics in patients with glioma IR Younis, S Malone, HS Friedman, LJ Schaaf, WP Petros Cancer chemotherapy and pharmacology 63, 517-524, 2009 | 42 | 2009 |
| Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1 IR Younis, M Elliott, CJ Peer, AJL Cooper, JT Pinto, GW Konat, ... Journal of Pharmacology and Experimental Therapeutics 327 (3), 770-776, 2008 | 41 | 2008 |
| Assessment of hepatic impairment and implications for pharmacokinetics of substance use treatment AH Talal, CS Venuto, I Younis Clinical pharmacology in drug development 6 (2), 206-212, 2017 | 39 | 2017 |
| A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE) KE Bullock, WP Petros, I Younis, HE Uronis, MA Morse, GC Blobe, ... Cancer chemotherapy and pharmacology 67, 465-474, 2011 | 33 | 2011 |
| The trend of increasing placebo response and decreasing treatment effect in schizophrenia trials continues: an update from the US Food and Drug Administration M Gopalakrishnan, H Zhu, TR Farchione, M Mathis, M Mehta, R Uppoor, ... The Journal of Clinical Psychiatry 81 (2), 14594, 2020 | 28 | 2020 |
| Metabolism of the cysteine S-conjugate of busulfan involves a β-lyase reaction AJL Cooper, IR Younis, ZV Niatsetskaya, BF Krasnikov, JT Pinto, ... Drug metabolism and disposition 36 (8), 1546-1552, 2008 | 24 | 2008 |
| Direct-injection mass spectrometric method for the rapid identification of fentanyl and norfentanyl in postmortem urine of six drug-overdose cases CJ Peer, DM Shakleya, IR Younis, JC Kraner, PS Callery Journal of analytical toxicology 31 (8), 515-521, 2007 | 24 | 2007 |
| Stable isotope pharmacokinetic studies provide insight into effects of age, sex, and weight on levothyroxine metabolism IR Younis, MA Ahmed, KD Burman, OP Soldin, J Jonklaas Thyroid 28 (1), 41-49, 2018 | 18 | 2018 |
| Epoxidation of the methamphetamine pyrolysis product, trans-phenylpropene, to trans-phenylpropylene oxide by CYP enzymes and stereoselective glutathione adduct formation M Sanga, IR Younis, PS Tirumalai, TM Bland, M Banaszewska, GW Konat, ... Toxicology and applied pharmacology 211 (2), 148-156, 2006 | 18 | 2006 |
| Association of end point definition and randomized clinical trial duration in clinical trials of schizophrenia medications IR Younis, M Gopalakrishnan, M Mathis, M Mehta, R Uppoor, H Zhu, ... JAMA psychiatry 77 (10), 1064-1071, 2020 | 17 | 2020 |
| Drug‐drug interaction studies of methadone and antiviral drugs: Lessons learned IR Younis, EA Lakota, DA Volpe, V Patel, Y Xu, CG Sahajwalla The Journal of Clinical Pharmacology 59 (8), 1035-1043, 2019 | 16 | 2019 |
| Utility of model‐based approaches for informing dosing recommendations in specific populations: report from the public AAPS Workshop IR Younis, J Robert Powell, A Rostami‐Hodjegan, B Corrigan, ... The Journal of Clinical Pharmacology 57 (1), 105-109, 2017 | 16 | 2017 |
| Dosing recommendations for quetiapine when coadministered with HIV protease inhibitors MR Sampson, KY Cao, PL Gish, K Hyon, P Mishra, W Tauber, P Zhao, ... The journal of clinical pharmacology 59 (4), 500-509, 2019 | 15 | 2019 |
| Longitudinal comparison of thyroxine pharmacokinetics between pregnant and nonpregnant women: a stable isotope study OP Soldin, SJ Soldin, AA Vinks, I Younis, HJ Landy Therapeutic drug monitoring 32 (6), 767-773, 2010 | 15 | 2010 |
| Treatment and prevention of CMV disease in transplant recipients: current knowledge and future perspectives AC Hodowanec, A Pikis, TE Komatsu, MR Sampson, IR Younis, JJ O'Rear, ... The Journal of Clinical Pharmacology 59 (6), 784-798, 2019 | 14 | 2019 |
| Adverse event detection and labeling in pediatric drug development: antiretroviral drugs JD Momper, Y Chang, M Jackson, P Schuette, S Seo, I Younis, ... Therapeutic Innovation & Regulatory Science 49 (2), 302-309, 2015 | 14 | 2015 |
| Utilizing PBPK modeling to evaluate the potential of a significant drug–drug interaction between clopidogrel and dasabuvir: a scientific perspective V Arya, P Zhao, KS Reynolds, P Mishra, IR Younis Clinical Pharmacology & Therapeutics 102 (4), 578-580, 2017 | 12 | 2017 |
