| The janus kinases (jaks) K Yamaoka, P Saharinen, M Pesu, VET Holt, O Silvennoinen, JJ O'Shea Genome biology 5, 1-6, 2004 | 791 | 2004 |
| CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-β–dependent manner J Andersson, DQ Tran, M Pesu, TS Davidson, H Ramsey, JJ O'Shea, ... The Journal of experimental medicine 205 (9), 1975-1981, 2008 | 469 | 2008 |
| A new modality for immunosuppression: targeting the JAK/STAT pathway JJ O'shea, M Pesu, DC Borie, PS Changelian Nature reviews Drug discovery 3 (7), 555-564, 2004 | 389 | 2004 |
| Therapeutic targeting of Janus kinases M Pesu, A Laurence, N Kishore, SH Zwillich, G Chan, JJ O'Shea Immunological reviews 223 (1), 132-142, 2008 | 329 | 2008 |
| T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance M Pesu, WT Watford, L Wei, L Xu, I Fuss, W Strober, J Andersson, ... Nature 455 (7210), 246-250, 2008 | 244 | 2008 |
| Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II J Yang, S Aittomäki, M Pesu, K Carter, J Saarinen, N Kalkkinen, E Kieff, ... The EMBO journal, 2002 | 219 | 2002 |
| Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs M Pesu, F Candotti, M Husa, SR Hofmann, LD Notarangelo, JJ O'Shea Immunological reviews 203 (1), 127-142, 2005 | 196 | 2005 |
| Therapeutic targeting of the Jak/STAT pathway S Aittomäki, M Pesu Basic & clinical pharmacology & toxicology 114 (1), 18-23, 2014 | 183 | 2014 |
| Mycobacterium marinum Causes a Latent Infection that Can Be Reactivated by Gamma Irradiation in Adult Zebrafish M Parikka, MM Hammaren, SKE Harjula, NJA Halfpenny, KE Oksanen, ... Public Library of Science 8 (9), e1002944, 2012 | 150 | 2012 |
| Examining the Chirality, Conformation and Selective Kinase Inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3 … J Jiang, K Ghoreschi, F Deflorian, Z Chen, M Perreira, M Pesu, J Smith, ... Journal of medicinal chemistry 51 (24), 8012-8018, 2008 | 144 | 2008 |
| S-layer protein mediates the stimulatory effect of Lactobacillus helveticus MIMLh5 on innate immunity V Taverniti, M Stuknyte, M Minuzzo, S Arioli, I De Noni, C Scabiosi, ... Applied and environmental microbiology 79 (4), 1221-1231, 2013 | 122 | 2013 |
| Suppl 2: JAK kinases in health and disease: an update A Laurence, M Pesu, O Silvennoinen, J O’Shea The open rheumatology journal 6, 232, 2012 | 118 | 2012 |
| Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii WT Watford, BD Hissong, LR Durant, H Yamane, LM Muul, Y Kanno, ... The Journal of experimental medicine 205 (12), 2803-2812, 2008 | 108 | 2008 |
| Cooperation among Stat1, glucocorticoid receptor, and PU. 1 in transcriptional activation of the high-affinity Fcγ receptor I in monocytes S Aittomäki, M Pesu, B Groner, OA Jänne, JJ Palvimo, O Silvennoinen The Journal of Immunology 164 (11), 5689-5697, 2000 | 99 | 2000 |
| Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL H Turpeinen, E Raitoharju, A Oksanen, N Oksala, M Levula, ... Atherosclerosis 219 (2), 799-806, 2011 | 95 | 2011 |
| Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma M Pesu, L Muul, Y Kanno, JJ O'Shea Blood 108 (3), 983-985, 2006 | 95 | 2006 |
| Interleukin-4-induced transcriptional activation by stat6 involves multiple serine/threonine kinase pathways and serine phosphorylation of stat6 M Pesu, K Takaluoma, S Aittomäki, A Lagerstedt, K Saksela, ... Blood, The Journal of the American Society of Hematology 95 (2), 494-502, 2000 | 89 | 2000 |
| Safety and efficacy of AMG 714 in adults with coeliac disease exposed to gluten challenge: a phase 2a, randomised, double-blind, placebo-controlled study ML Lähdeaho, M Scheinin, P Vuotikka, J Taavela, A Popp, J Laukkarinen, ... The Lancet Gastroenterology & Hepatology 4 (12), 948-959, 2019 | 84 | 2019 |
| New strategies for immunosuppression: interfering with cytokines by targeting the Jak/Stat pathway JJ O'Shea, H Park, M Pesu, D Borie, P Changelian Current opinion in rheumatology 17 (3), 305-311, 2005 | 76 | 2005 |
| Genetics of the first seven proprotein convertase enzymes in health and disease H Turpeinen, Z Ortutay, M Pesu Current genomics 14 (7), 453-467, 2013 | 68 | 2013 |
