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Christopher J. Lynch
Christopher J. Lynch
Office of Nutrition Research, NIDDK, National Institutes of Health
在 psu.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Branched-chain amino acids in metabolic signalling and insulin resistance
CJ Lynch, SH Adams
Nature Reviews Endocrinology 10 (12), 723-736, 2014
12872014
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
P She, C Van Horn, T Reid, SM Hutson, RN Cooney, CJ Lynch
American Journal of Physiology-Endocrinology and Metabolism 293 (6), E1552-E1563, 2007
5362007
Catabolic defect of branched-chain amino acids promotes heart failure
H Sun, KC Olson, C Gao, DA Prosdocimo, M Zhou, Z Wang, D Jeyaraj, ...
Circulation 133 (21), 2038-2049, 2016
4512016
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels
MA Herman, P She, OD Peroni, CJ Lynch, BB Kahn
Journal of Biological Chemistry 285 (15), 11348-11356, 2010
4062010
Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle
P She, TM Reid, SK Bronson, TC Vary, A Hajnal, CJ Lynch, SM Hutson
Cell metabolism 6 (3), 181-194, 2007
3942007
Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
DE Lackey, CJ Lynch, KC Olson, R Mostaedi, M Ali, WH Smith, F Karpe, ...
American Journal of Physiology-Endocrinology and Metabolism 304 (11), E1175 …, 2013
3302013
Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity
J Li, C Romestaing, X Han, Y Li, X Hao, Y Wu, C Sun, X Liu, LS Jefferson, ...
Cell metabolism 12 (2), 154-165, 2010
2982010
Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate.
CJ Lynch, R Charest, SB Bocckino, JH Exton, PF Blackmore
Journal of Biological Chemistry 260 (5), 2844-2851, 1985
2641985
Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue
CJ Lynch, BJ Patson, J Anthony, A Vaval, LS Jefferson, TC Vary
American Journal of Physiology-Endocrinology and Metabolism 283 (3), E503-E513, 2002
2252002
Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells
G Lu, H Sun, P She, JY Youn, S Warburton, P Ping, TM Vondriska, H Cai, ...
The Journal of clinical investigation 119 (6), 1678-1687, 2009
2172009
Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents
VL Albaugh, CR Henry, NT Bello, A Hajnal, SL Lynch, B Halle, CJ Lynch
Obesity 14 (1), 36-51, 2006
2132006
Role of leucine in the regulation of mTOR by amino acids: revelations from structure–activity studies
CJ Lynch
The Journal of nutrition 131 (3), 861S-865S, 2001
2112001
Regulation of amino acid–sensitive TOR signaling by leucine analogues in adipocytes
CJ Lynch, HL Fox, TC Vary, LS Jefferson, SR Kimball
Journal of cellular biochemistry 77 (2), 234-251, 2000
1952000
Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice
NM Agostino, VM Chinchilli, CJ Lynch, A Koszyk-Szewczyk, R Gingrich, ...
Journal of Oncology Pharmacy Practice 17 (3), 197-202, 2011
1842011
Leucine in food mediates some of the postprandial rise in plasma leptin concentrations
CJ Lynch, B Gern, C Lloyd, SM Hutson, R Eicher, TC Vary
American Journal of Physiology-Endocrinology and Metabolism 291 (3), E621-E630, 2006
1752006
Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats
CJ Lynch, SM Hutson, BJ Patson, A Vaval, TC Vary
American Journal of Physiology-Endocrinology and Metabolism 283 (4), E824-E835, 2002
1712002
Amino acids stimulate phosphorylation of p70 S6k and organization of rat adipocytes into multicellular clusters
HL Fox, SR Kimball, LS Jefferson, CJ Lynch
American Journal of Physiology-Cell Physiology 274 (1), C206-C213, 1998
1631998
Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism
AC Shin, M Fasshauer, N Filatova, LA Grundell, E Zielinski, JY Zhou, ...
Cell metabolism 20 (5), 898-909, 2014
1612014
Amino acid effects on translational repressor 4E-BP1 are mediated primarily by L-leucine in isolated adipocytes
HL Fox, PT Pham, SR Kimball, LS Jefferson, CJ Lynch
American Journal of Physiology-Cell Physiology 275 (5), C1232-C1238, 1998
1531998
Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats
A Hajnal, P Kovacs, T Ahmed, K Meirelles, CJ Lynch, RN Cooney
American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (4 …, 2010
1522010
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