| Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes RN Kulkarni, JC Brüning, JN Winnay, C Postic, MA Magnuson, CR Kahn Cell 96 (3), 329-339, 1999 | 1508 | 1999 |
| A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance JC Brüning, MD Michael, JN Winnay, T Hayashi, D Hörsch, D Accili, ... Molecular cell 2 (5), 559-569, 1998 | 1452 | 1998 |
| Adipose-derived circulating miRNAs regulate gene expression in other tissues T Thomou, MA Mori, JM Dreyfuss, M Konishi, M Sakaguchi, C Wolfrum, ... Nature 542 (7642), 450-455, 2017 | 1366 | 2017 |
| New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure YH Tseng, E Kokkotou, TJ Schulz, TL Huang, JN Winnay, CM Taniguchi, ... Nature 454 (7207), 1000-1004, 2008 | 1295 | 2008 |
| Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles JC Brüning, J Winnay, S Bonner-Weir, SI Taylor, D Accili, CR Kahn Cell 88 (4), 561-572, 1997 | 703 | 1997 |
| Altered function of insulin receptor substrate-1–deficient mouse islets and cultured β-cell lines RN Kulkarni, JN Winnay, M Daniels, JC Brüning, SN Flier, D Hanahan, ... The Journal of clinical investigation 104 (12), R69-R75, 1999 | 341 | 1999 |
| PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance RN Kulkarni, US Jhala, JN Winnay, S Krajewski, M Montminy, CR Kahn The Journal of clinical investigation 114 (6), 828-836, 2004 | 318 | 2004 |
| Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells JC Brüning, J Winnay, B Cheatham, CR Kahn Molecular and cellular biology 17 (3), 1513-1521, 1997 | 293 | 1997 |
| A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–binding protein-1 to modulate the unfolded protein response JN Winnay, J Boucher, MA Mori, K Ueki, CR Kahn Nature medicine 16 (4), 438-445, 2010 | 218 | 2010 |
| Phosphorylation of C/EBPα inhibits granulopoiesis SE Ross, HS Radomska, B Wu, P Zhang, JN Winnay, L Bajnok, ... Molecular and cellular biology, 2004 | 188 | 2004 |
| Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2 A Assmann, K Ueki, JN Winnay, T Kadowaki, RN Kulkarni Molecular and cellular biology 29 (11), 3219-3228, 2009 | 184 | 2009 |
| Specific roles of the p110α isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation VR Sopasakis, P Liu, R Suzuki, T Kondo, J Winnay, TT Tran, T Asano, ... Cell Metabolism 11 (3), 220-230, 2010 | 179 | 2010 |
| The phosphoinositide 3-kinase regulatory subunit p85α can exert tumor suppressor properties through negative regulation of growth factor signaling CM Taniguchi, J Winnay, T Kondo, RT Bronson, AR Guimaraes, ... Cancer research 70 (13), 5305-5315, 2010 | 165 | 2010 |
| Micro RNA‐455 regulates brown adipogenesis via a novel HIF 1an‐AMPK‐PGC 1α signaling network H Zhang, M Guan, KL Townsend, TL Huang, D An, X Yan, R Xue, ... EMBO reports 16 (10), 1378-1393, 2015 | 161 | 2015 |
| Domain-dependent effects of insulin and IGF-1 receptors on signalling and gene expression W Cai, M Sakaguchi, A Kleinridders, G Gonzalez-Del Pino, JM Dreyfuss, ... Nature communications 8 (1), 14892, 2017 | 150 | 2017 |
| Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice RN Kulkarni, K Almind, HJ Goren, JN Winnay, K Ueki, T Okada, CR Kahn Diabetes 52 (6), 1528-1534, 2003 | 140 | 2003 |
| SHORT syndrome with partial lipodystrophy due to impaired phosphatidylinositol 3 kinase signaling KK Chudasama, J Winnay, S Johansson, T Claudi, R König, I Haldorsen, ... The American Journal of Human Genetics 93 (1), 150-157, 2013 | 136 | 2013 |
| Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5) J Palsgaard, B Emanuelli, JN Winnay, G Sumara, G Karsenty, CR Kahn Journal of Biological Chemistry 287 (15), 12016-12026, 2012 | 127 | 2012 |
| Adipocyte dynamics and reversible metabolic syndrome in mice with an inducible adipocyte-specific deletion of the insulin receptor M Sakaguchi, S Fujisaka, W Cai, JN Winnay, M Konishi, BT O'Neill, M Li, ... Cell Metabolism 25 (2), 448-462, 2017 | 126 | 2017 |
| Convergence of Wnt signaling and steroidogenic factor-1 (SF-1) on transcription of the rat inhibin α gene BM Gummow, JN Winnay, GD Hammer Journal of Biological Chemistry 278 (29), 26572-26579, 2003 | 121 | 2003 |
Marcelo A. MoriDepartment of Biochemistry and Tissue Biology - Institute of Biology - State University of Campinas在 unicamp.br 的电子邮件经过验证
