| Design, synthesis and docking studies of novel thienopyrimidine derivatives bearing chromone moiety as mTOR/PI3Kα inhibitors W Zhu, C Chen, C Sun, S Xu, C Wu, F Lei, H Xia, Q Tu, P Zheng European journal of medicinal chemistry 93, 64-73, 2015 | 67 | 2015 |
| Design, synthesis and antitumor activity of Novel Sorafenib derivatives bearing pyrazole scaffold M Wang, S Xu, H Lei, C Wang, Z Xiao, S Jia, J Zhi, P Zheng, W Zhu Bioorganic & medicinal chemistry 25 (20), 5754-5763, 2017 | 57 | 2017 |
| Synthesis and Anticancer Activity of Indolin‐2‐one Derivatives Bearing the 4‐Thiazolidinone Moiety S Wang, Y Zhao, W Zhu, Y Liu, K Guo, P Gong Archiv der Pharmazie 345 (1), 73-80, 2012 | 56 | 2012 |
| The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation J He, Z Zhou, X Sun, Z Yang, P Zheng, S Xu, W Zhu European Journal of Medicinal Chemistry 210, 112995, 2021 | 51 | 2021 |
| Synthesis and anticancer activity of novel 4-morpholino-7, 8-dihydro-5H-thiopyrano [4, 3-d] pyrimidine derivatives bearing chromone moiety C Sun, C Chen, S Xu, J Wang, Y Zhu, D Kong, H Tao, M Jin, P Zheng, ... Bioorganic & Medicinal Chemistry 24 (16), 3862-3869, 2016 | 51 | 2016 |
| Design, synthesis, anticancer activity and docking studies of novel 4-morpholino-7, 8-dihydro-5H-thiopyrano [4, 3-d] pyrimidine derivatives as mTOR inhibitors W Zhu, C Sun, S Xu, C Wu, J Wu, M Xu, H Zhao, L Chen, W Zeng, ... Bioorganic & medicinal chemistry 22 (24), 6746-6754, 2014 | 51 | 2014 |
| Design, synthesis and 3D-QSAR analysis of novel 2-hydrazinyl-4-morpholinothieno [3, 2-d] pyrimidine derivatives as potential antitumor agents W Zhu, Y Liu, X Zhai, X Wang, Y Zhu, D Wu, H Zhou, P Gong, Y Zhao European journal of medicinal chemistry 57, 162-175, 2012 | 48 | 2012 |
| Biomineralized cascade enzyme-encapsulated ZIF-8 nanoparticles combined with antisense oligonucleotides for drug-resistant bacteria treatment Y Zhang, L Lai, Y Liu, B Chen, J Yao, P Zheng, Q Pan, W Zhu ACS Applied Materials & Interfaces 14 (5), 6453-6464, 2022 | 43 | 2022 |
| Synthesis, and docking studies of phenylpyrimidine-carboxamide derivatives bearing 1H-pyrrolo [2, 3-b] pyridine moiety as c-Met inhibitors W Zhu, W Wang, S Xu, J Wang, Q Tang, C Wu, Y Zhao, P Zheng Bioorganic & medicinal chemistry 24 (8), 1749-1756, 2016 | 43 | 2016 |
| Discovery of novel pyrrolo [2, 3-b] pyridine derivatives bearing 1, 2, 3-triazole moiety as c-Met kinase inhibitors Q Tang, L Wang, Y Tu, W Zhu, R Luo, Q Tu, P Wang, C Wu, P Gong, ... Bioorganic & medicinal chemistry letters 26 (7), 1680-1684, 2016 | 43 | 2016 |
| A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts F Wang, L Wang, Y Zhao, Y Li, G Ping, S Xiao, K Chen, W Zhu, P Gong, ... Molecular oncology 8 (8), 1640-1652, 2014 | 42 | 2014 |
| Design, synthesis, activity and docking study of sorafenib analogs bearing sulfonylurea unit C Wu, M Wang, Q Tang, R Luo, L Chen, P Zheng, W Zhu Molecules 20 (10), 19361-19371, 2015 | 41 | 2015 |
| Carboxymethyl chitosan/phospholipid bilayer-capped mesoporous carbon nanoparticles with pH-responsive and prolonged release properties for oral delivery of the antitumor drug … Y Zhang, W Zhu, H Zhang, J Han, L Zhang, Q Lin, F Ai International journal of pharmaceutics 532 (1), 384-392, 2017 | 40 | 2017 |
| Design, synthesis, and docking studies of afatinib analogs bearing cinnamamide moiety as potent EGFR inhibitors Y Tu, Y OuYang, S Xu, Y Zhu, G Li, C Sun, P Zheng, W Zhu Bioorganic & medicinal chemistry 24 (7), 1495-1503, 2016 | 39 | 2016 |
| Design, synthesis, and docking studies of quinazoline analogues bearing aryl semicarbazone scaffolds as potent EGFR inhibitors Y Tu, C Wang, S Xu, Z Lan, W Li, J Han, Y Zhou, P Zheng, W Zhu Bioorganic & medicinal chemistry 25 (12), 3148-3157, 2017 | 37 | 2017 |
| Design, synthesis and activity of novel sorafenib analogues bearing chalcone unit M Wang, S Xu, C Wu, X Liu, H Tao, Y Huang, Y Liu, P Zheng, W Zhu Bioorganic & Medicinal Chemistry Letters 26 (22), 5450-5454, 2016 | 36 | 2016 |
| Design, synthesis, biological evaluation and docking studies of novel 2-substituted-4-morpholino-7, 8-dihydro-5H-thiopyrano [4, 3-d] pyrimidine derivatives as dual PI3Kα/mTOR … F Lei, C Sun, S Xu, Q Wang, Y OuYang, C Chen, H Xia, L Wang, P Zheng, ... European Journal of Medicinal Chemistry 116, 27-35, 2016 | 36 | 2016 |
| Discovery of novel 6, 7-disubstituted-4-phenoxyquinoline derivatives bearing 5-(aminomethylene) pyrimidine-2, 4, 6-trione moiety as c-Met kinase inhibitors Q Tang, G Zhang, X Du, W Zhu, R Li, H Lin, P Li, M Cheng, P Gong, ... Bioorganic & medicinal chemistry 22 (4), 1236-1249, 2014 | 36 | 2014 |
| Design, synthesis and antitumor activity of novel artemisinin derivatives using hybrid approach L Xie, X Zhai, L Ren, H Meng, C Liu, W Zhu, Y Zhao Chemical and Pharmaceutical Bulletin 59 (8), 984-990, 2011 | 36 | 2011 |
| Discovery of thinopyrimidine-triazole conjugates as c-Met targeting and apoptosis inducing agents L Wang, S Xu, X Liu, X Chen, H Xiong, S Hou, W Zou, Q Tang, P Zheng, ... Bioorganic Chemistry 77, 370-380, 2018 | 35 | 2018 |
