| Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis S Aarabi, KA Bhatt, Y Shi, J Paterno, EI Chang, SA Loh, JW Holmes, ... The FASEB Journal 21 (12), 3250-3261, 2007 | 613 | 2007 |
| Structure and mechanics of healing myocardial infarcts JW Holmes, TK Borg, JW Covell Annu. Rev. Biomed. Eng. 7 (1), 223-253, 2005 | 499 | 2005 |
| Guidelines for experimental models of myocardial ischemia and infarction ML Lindsey, R Bolli, JM Canty Jr, XJ Du, NG Frangogiannis, S Frantz, ... American Journal of Physiology-Heart and Circulatory Physiology 314 (4 …, 2018 | 496 | 2018 |
| Modelling cardiac mechanical properties in three dimensions KD Costa, JW Holmes, AD McCulloch Philosophical transactions of the Royal Society of London. Series A …, 2001 | 375 | 2001 |
| Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling LE Freed, F Guilak, XE Guo, ML Gray, R Tranquillo, JW Holmes, ... Tissue engineering 12 (12), 3285-3305, 2006 | 369 | 2006 |
| Chronic unloading by left ventricular assist device reverses contractile dysfunction and alters gene expression in end-stage heart failure PM Heerdt, JW Holmes, B Cai, A Barbone, JD Madigan, S Reiken, DL Lee, ... Circulation 102 (22), 2713-2719, 2000 | 364 | 2000 |
| Contribution of extracellular matrix to the mechanical properties of the heart GM Fomovsky, S Thomopoulos, JW Holmes Journal of molecular and cellular cardiology 48 (3), 490-496, 2010 | 302 | 2010 |
| Physiological implications of myocardial scar structure WJ Richardson, SA Clarke, TA Quinn, JW Holmes Comprehensive Physiology 5 (4), 1877, 2015 | 300 | 2015 |
| Evolution of scar structure, mechanics, and ventricular function after myocardial infarction in the rat GM Fomovsky, JW Holmes American Journal of Physiology-Heart and Circulatory Physiology 298 (1 …, 2010 | 255 | 2010 |
| Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane BM Kenwood, JL Weaver, A Bajwa, IK Poon, FL Byrne, BA Murrow, ... Molecular metabolism 3 (2), 114-123, 2014 | 241 | 2014 |
| Comparison of right and left ventricular responses to left ventricular assist device support in patients with severe heart failure A Barbone, JW Holmes, PM Heerdt, Y Naka, N Joshi, M Daines, AR Marks, ... Circulation 104 (6), 670-675, 2001 | 235* | 2001 |
| Creating alignment and anisotropy in engineered heart tissue: role of boundary conditions in a model three-dimensional culture system KD Costa, EJ Lee, JW Holmes Tissue engineering 9 (4), 567-577, 2003 | 198 | 2003 |
| LV volume quantification via spatiotemporal analysis of real-time 3-D echocardiography ED Angelini, AF Laine, S Takuma, JW Holmes, S Homma IEEE transactions on medical imaging 20 (6), 457-469, 2001 | 155 | 2001 |
| Impact of mechanical activation, scar, and electrical timing on cardiac resynchronization therapy response and clinical outcomes KC Bilchick, S Kuruvilla, YS Hamirani, R Ramachandran, SA Clarke, ... Journal of the American College of Cardiology 63 (16), 1657-1666, 2014 | 150 | 2014 |
| The development of structural and mechanical anisotropy in fibroblast populated collagen gels S Thomopoulos, GM Fomovsky, JW Holmes | 148 | 2005 |
| Functional implications of myocardial scar structure JW Holmes, JA Nuñez, JW Covell American Journal of Physiology-Heart and Circulatory Physiology 272 (5 …, 1997 | 142 | 1997 |
| Segmentation of real-time three-dimensional ultrasound for quantification of ventricular function: a clinical study on right and left ventricles ED Angelini, S Homma, G Pearson, JW Holmes, AF Laine Ultrasound in medicine & biology 31 (9), 1143-1158, 2005 | 133 | 2005 |
| Theoretical quality assessment of myocardial elastography with in vivo validation WN Lee, CM Ingrassia, KD Costa, JW Holmes, EE Konofagou ieee transactions on ultrasonics, ferroelectrics, and frequency control 54 …, 2007 | 131 | 2007 |
| Regional mechanics determine collagen fiber structure in healing myocardial infarcts GM Fomovsky, AD Rouillard, JW Holmes Journal of molecular and cellular cardiology 52 (5), 1083-1090, 2012 | 126 | 2012 |
| Left ventricular assist device support normalizes left and right ventricular beta-adrenergic pathway properties S Klotz, A Barbone, S Reiken, JW Holmes, Y Naka, MC Oz, AR Marks, ... Journal of the American College of Cardiology 45 (5), 668-676, 2005 | 118 | 2005 |
