Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibers RL Anderson, DV Trivedi, SS Sarkar, M Henze, W Ma, H Gong, ... Proceedings of the National Academy of Sciences 115 (35), E8143-E8152, 2018 | 302 | 2018 |
Myosin head configurations in resting and contracting murine skeletal muscle W Ma, H Gong, T Irving International journal of molecular sciences 19 (9), 2643, 2018 | 57 | 2018 |
Thick-filament extensibility in intact skeletal muscle W Ma, H Gong, B Kiss, EJ Lee, H Granzier, T Irving Biophysical journal 115 (8), 1580-1588, 2018 | 52 | 2018 |
The super-relaxed state and length dependent activation in porcine myocardium W Ma, M Henze, RL Anderson, H Gong, FL Wong, CL Del Rio, T Irving Circulation research 129 (6), 617-630, 2021 | 50 | 2021 |
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin JD Powers, CC Yuan, KJ McCabe, JD Murray, MC Childers, GV Flint, ... Proceedings of the National Academy of Sciences 116 (23), 11502-11507, 2019 | 39 | 2019 |
Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle B Kiss, EJ Lee, W Ma, FW Li, P Tonino, SM Mijailovich, TC Irving, ... Proceedings of the National Academy of Sciences 115 (41), 10369-10374, 2018 | 39 | 2018 |
Small angle X-ray diffraction as a tool for structural characterization of muscle disease W Ma, TC Irving International Journal of Molecular Sciences 23 (6), 3052, 2022 | 34 | 2022 |
The myosin interacting-heads motif present in live tarantula muscle explains tetanic and posttetanic phosphorylation mechanisms R Padrón, W Ma, S Duno-Miranda, N Koubassova, KH Lee, A Pinto, ... Proceedings of the National Academy of Sciences 117 (22), 11865-11874, 2020 | 34 | 2020 |
KBTBD13 is an actin-binding protein that modulates muscle kinetics JM De Winter, JP Molenaar, M Yuen, R Van Der Pijl, S Shen, S Conijn, ... The Journal of clinical investigation 130 (2), 754-767, 2020 | 34 | 2020 |
Dysfunctional sarcomere contractility contributes to muscle weakness in ACTA1‐related nemaline myopathy (NEM3) B Joureau, JM de Winter, S Conijn, SJP Bogaards, I Kovacevic, ... Annals of neurology 83 (2), 269-282, 2018 | 31 | 2018 |
Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle D Gonzalez-Martinez, JR Johnston, M Landim-Vieira, W Ma, O Antipova, ... Journal of molecular and cellular cardiology 123, 26-37, 2018 | 30 | 2018 |
Mechanistic insights into enhancement or inhibition of phase separation by different polyubiquitin chains TP Dao, Y Yang, MF Presti, MS Cosgrove, JB Hopkins, W Ma, SN Loh, ... EMBO reports 23 (8), e55056, 2022 | 29 | 2022 |
Cardiac myosin filaments are directly regulated by calcium W Ma, H Gong, L Qi, S Nag, TC Irving | 29 | 2022 |
MuscleX: software suite for diffraction X-ray imaging V1. 13.1 J Jiratrakanvong, J Shao, M Menendez, X Li, J Li, W Ma, G Agam, T Irving Zenodo: Geneva, Switzerland, 2018 | 28 | 2018 |
Fast skeletal myosin-binding protein-C regulates fast skeletal muscle contraction T Song, JW McNamara, W Ma, M Landim-Vieira, KH Lee, LA Martin, ... Proceedings of the National Academy of Sciences 118 (17), e2003596118, 2021 | 26 | 2021 |
Molecular basis of force-pCa relation in MYL2 cardiomyopathy mice: Role of the super-relaxed state of myosin CC Yuan, K Kazmierczak, J Liang, W Ma, TC Irving, D Szczesna-Cordary Proceedings of the National Academy of Sciences 119 (8), e2110328119, 2022 | 25 | 2022 |
Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2′‐deoxy‐ATP W Ma, M Childers, J Murray, F Moussavi‐Harami, H Gong, R Weiss, ... The Journal of physiology 598 (22), 5165-5182, 2020 | 25 | 2020 |
Two classes of myosin inhibitors, para-nitroblebbistatin and mavacamten, stabilize β-cardiac myosin in different structural and functional states SK Gollapudi, W Ma, S Chakravarthy, AC Combs, N Sa, S Langer, ... Journal of molecular biology 433 (23), 167295, 2021 | 24 | 2021 |
Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force W Ma, TS McMillen, MC Childers, H Gong, M Regnier, T Irving Proceedings of the National Academy of Sciences 120 (5), e2207615120, 2023 | 23 | 2023 |
Titin force in muscle cells alters lattice order, thick and thin filament protein formation AL Hessel, W Ma, N Mazara, PE Rice, D Nissen, H Gong, M Kuehn, ... Proceedings of the National Academy of Sciences 119 (48), e2209441119, 2022 | 21 | 2022 |