Targeting oxidative stress for the treatment of liver fibrosis T Luangmonkong, S Suriguga, HAM Mutsaers, GMM Groothuis, P Olinga, ... Reviews of Physiology, Biochemistry and Pharmacology, Vol. 175, 71-102, 2018 | 236 | 2018 |
The kidney and uremic toxin removal: glomerulus or tubule? R Masereeuw, HAM Mutsaers, T Toyohara, T Abe, S Jhawar, DH Sweet, ... Seminars in nephrology 34 (2), 191-208, 2014 | 168 | 2014 |
Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations HAM Mutsaers, LP van den Heuvel, LHJ Ringens, ACA Dankers, ... PloS one 6 (4), e18438, 2011 | 144 | 2011 |
Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration HAM Mutsaers, MJG Wilmer, D Reijnders, J Jansen, PHH van den Broek, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (1), 142-150, 2013 | 128 | 2013 |
Curcumin‐induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation A Scharstuhl, HAM Mutsaers, SWC Pennings, WA Szarek, FGM Russel, ... Journal of cellular and molecular medicine 13 (4), 712-725, 2009 | 126 | 2009 |
A morphological and functional comparison of proximal tubule cell lines established from human urine and kidney tissue J Jansen, CMS Schophuizen, MJ Wilmer, SHM Lahham, HAM Mutsaers, ... Experimental cell research 323 (1), 87-99, 2014 | 114 | 2014 |
The influence of dietary protein intake on mammalian tryptophan and phenolic metabolites R Poesen, HAM Mutsaers, K Windey, PH Van Den Broek, V Verweij, ... PLoS One 10 (10), e0140820, 2015 | 101 | 2015 |
Evaluating the antifibrotic potency of galunisertib in a human ex vivo model of liver fibrosis T Luangmonkong, S Suriguga, E Bigaeva, M Boersema, D Oosterhuis, ... British Journal of Pharmacology 174 (18), 3107-3117, 2017 | 97 | 2017 |
Chronic kidney disease and fibrosis: the role of uremic retention solutes HAM Mutsaers, EGD Stribos, G Glorieux, R Vanholder, P Olinga Frontiers in medicine 2, 60, 2015 | 87 | 2015 |
Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis A Scharstuhl, HAM Mutsaers, SWC Pennings, FGM Russel, FA Wagener PloS one 4 (8), e6688, 2009 | 86 | 2009 |
Human precision-cut liver slices as a model to test antifibrotic drugs in the early onset of liver fibrosis IM Westra, HAM Mutsaers, T Luangmonkong, M Hadi, D Oosterhuis, ... Toxicology in Vitro 35, 77-85, 2016 | 80 | 2016 |
Optimized metabolomic approach to identify uremic solutes in plasma of stage 3–4 chronic kidney disease patients HAM Mutsaers, UFH Engelke, MJG Wilmer, JFM Wetzels, RA Wevers, ... Plos one 8 (8), e71199, 2013 | 70 | 2013 |
Precision-cut human kidney slices as a model to elucidate the process of renal fibrosis EGD Stribos, T Luangmonkong, AM Leliveld, IJ De Jong, WJ Van Son, ... Translational Research 170, 8-16. e1, 2016 | 69 | 2016 |
Proximal tubular efflux transporters involved in renal excretion of p-cresyl sulfate and p-cresyl glucuronide: Implications for chronic kidney disease pathophysiology HAM Mutsaers, P Caetano-Pinto, AEM Seegers, ACA Dankers, ... Toxicology in Vitro 29 (7), 1868-1877, 2015 | 67 | 2015 |
Mesenchymal stem cell-conditioned medium accelerates regeneration of human renal proximal tubule epithelial cells after gentamicin toxicity R Moghadasali, HAM Mutsaers, M Azarnia, N Aghdami, H Baharvand, ... Experimental and Toxicologic Pathology 65 (5), 595-600, 2013 | 66 | 2013 |
Dexamethasone enhances oxidative stress-induced cell death in murine neural stem cells HAM Mutsaers, R Tofighi Neurotoxicity research 22, 127-137, 2012 | 64 | 2012 |
Organ-and species-specific biological activity of rosmarinic acid R Iswandana, BT Pham, WT Van Haaften, T Luangmonkong, ... Toxicology in Vitro 32, 261-268, 2016 | 56 | 2016 |
Hyperuricemia influences tryptophan metabolism via inhibition of multidrug resistance protein 4 (MRP4) and breast cancer resistance protein (BCRP) ACA Dankers, HAM Mutsaers, HBPM Dijkman, LP van den Heuvel, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (10 …, 2013 | 52 | 2013 |
Activation of the prostaglandin E2 EP2 receptor attenuates renal fibrosis in unilateral ureteral obstructed mice and human kidney slices MS Jensen, HAM Mutsaers, SJ Tingskov, M Christensen, MG Madsen, ... Acta Physiologica 227 (1), e13291, 2019 | 48 | 2019 |
Renal fibrosis in precision-cut kidney slices EGD Stribos, JL Hillebrands, P Olinga, HAM Mutsaers European journal of pharmacology 790, 57-61, 2016 | 45 | 2016 |