Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis Y Zheng, DM Danilenko, P Valdez, I Kasman, J Eastham-Anderson, J Wu, ... Nature 445 (7128), 648-651, 2007 | 2473 | 2007 |
Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis J Ridgway, G Zhang, Y Wu, S Stawicki, WC Liang, Y Chanthery, ... Nature 444 (7122), 1083-1087, 2006 | 1203 | 2006 |
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma R Chen, MC Nishimura, SM Bumbaca, S Kharbanda, WF Forrest, ... Cancer cell 17 (4), 362-375, 2010 | 703 | 2010 |
PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment Y Crawford, I Kasman, L Yu, C Zhong, X Wu, Z Modrusan, J Kaminker, ... Cancer cell 15 (1), 21-34, 2009 | 696 | 2009 |
The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis SM Sa, PA Valdez, J Wu, K Jung, F Zhong, L Hall, I Kasman, J Winer, ... The Journal of Immunology 178 (4), 2229-2240, 2007 | 629 | 2007 |
Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway G Zhuang, X Wu, Z Jiang, I Kasman, J Yao, Y Guan, J Oeh, Z Modrusan, ... The EMBO journal 31 (17), 3513-3523, 2012 | 533 | 2012 |
An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy AS Chung, X Wu, G Zhuang, H Ngu, I Kasman, J Zhang, JM Vernes, ... Nature medicine 19 (9), 1114-1123, 2013 | 496 | 2013 |
Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3 Y Xu, L Yuan, J Mak, L Pardanaud, M Caunt, I Kasman, B Larrivée, ... Journal of Cell Biology 188 (1), 115-130, 2010 | 422 | 2010 |
Blocking neuropilin-2 function inhibits tumor cell metastasis M Caunt, J Mak, WC Liang, S Stawicki, Q Pan, RK Tong, J Kowalski, C Ho, ... Cancer cell 13 (4), 331-342, 2008 | 421 | 2008 |
MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival H Jin, R Yang, Z Zheng, M Romero, J Ross, H Bou-Reslan, RAD Carano, ... Cancer research 68 (11), 4360-4368, 2008 | 310 | 2008 |
Intermittent administration of MEK inhibitor GDC-0973 plus PI3K inhibitor GDC-0941 triggers robust apoptosis and tumor growth inhibition KP Hoeflich, M Merchant, C Orr, J Chan, D Den Otter, L Berry, I Kasman, ... Cancer research 72 (1), 210-219, 2012 | 275 | 2012 |
EGFL7 regulates the collective migration of endothelial cells by restricting their spatial distribution M Schmidt, K Paes, A De Mazière, T Smyczek, S Yang, A Gray, D French, ... Oxford University Press for The Company of Biologists Limited 134 (16), 2913 …, 2007 | 257 | 2007 |
PlGF blockade does not inhibit angiogenesis during primary tumor growth C Bais, X Wu, J Yao, S Yang, Y Crawford, K McCutcheon, C Tan, ... Cell 141 (1), 166-177, 2010 | 179 | 2010 |
Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy A Bagri, L Berry, B Gunter, M Singh, I Kasman, LA Damico, H Xiang, ... Clinical Cancer Research 16 (15), 3887-3900, 2010 | 172 | 2010 |
Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy J Yao, X Wu, G Zhuang, IM Kasman, T Vogt, V Phan, M Shibuya, ... Proceedings of the National Academy of Sciences 108 (28), 11590-11595, 2011 | 116 | 2011 |
Uniform overexpression and rapid accessibility of α5β1 integrin on blood vessels in tumors P Parsons-Wingerter, IM Kasman, S Norberg, A Magnussen, S Zanivan, ... The American journal of pathology 167 (1), 193-211, 2005 | 97 | 2005 |
Effects of an Anti–VEGF-A monoclonal antibody on laser-induced choroidal neovascularization in mice: optimizing methods to quantify vascular changes C Campa, I Kasman, W Ye, WP Lee, G Fuh, N Ferrara Investigative ophthalmology & visual science 49 (3), 1178-1183, 2008 | 94 | 2008 |
Anti‐VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models M Singh, SS Couto, WF Forrest, A Lima, JH Cheng, R Molina, JE Long, ... The Journal of pathology 227 (4), 417-430, 2012 | 86 | 2012 |
Inhibition of VEGF-A prevents the angiogenic switch and results in increased survival of Apc+/min mice N Korsisaari, IM Kasman, WF Forrest, N Pal, W Bai, G Fuh, FV Peale, ... Proceedings of the National Academy of Sciences 104 (25), 10625-10630, 2007 | 84 | 2007 |
Rapid Access of Antibodies to α5β1 Integrin Overexpressed on the Luminal Surface of Tumor Blood Vessels A Magnussen, IM Kasman, S Norberg, P Baluk, R Murray, DM McDonald Cancer Research 65 (7), 2712-2721, 2005 | 80 | 2005 |