RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors PI Thakore, JB Kwon, CE Nelson, DC Rouse, MP Gemberling, ML Oliver, ... Nature communications 9 (1), 1674, 2018 | 155 | 2018 |
Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity Y Zhang, H El-Sikhry, KR Chaudhary, SN Batchu, A Shayeganpour, ... American Journal of Physiology-Heart and Circulatory Physiology 297 (1), H37-H46, 2009 | 120 | 2009 |
Transgenic mice for in vivo epigenome editing with CRISPR-based systems MP Gemberling, K Siklenka, E Rodriguez, KR Tonn-Eisinger, A Barrera, ... Nature methods 18 (8), 965-974, 2021 | 80 | 2021 |
Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis L Wang, ER Ko, JJ Gilchrist, KJ Pittman, A Rautanen, M Pirinen, ... Science Advances 3 (3), e1602096, 2017 | 57 | 2017 |
Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways JA Somarelli, D Schaeffer, MS Marengo, T Bepler, D Rouse, KE Ware, ... Oncogene 35 (33), 4302-4311, 2016 | 50 | 2016 |
Polymer-mediated inhibition of pro-invasive nucleic acid DAMPs and microvesicles limits pancreatic cancer metastasis I Naqvi, R Gunaratne, JE McDade, A Moreno, RE Rempel, DC Rouse, ... Molecular Therapy 26 (4), 1020-1031, 2018 | 49 | 2018 |
Increased Ca2+ signaling through CaV1. 2 promotes bone formation and prevents estrogen deficiency–induced bone loss C Cao, Y Ren, AS Barnett, AJ Mirando, D Rouse, SH Mun, KH Park-Min, ... JCI insight 2 (22), 2017 | 41 | 2017 |
The genetic contribution to heart rate and heart rate variability in quiescent mice R Howden, E Liu, L Miller-DeGraff, HL Keener, C Walker, JA Clark, ... American Journal of Physiology-Heart and Circulatory Physiology 295 (1), H59-H68, 2008 | 31 | 2008 |
Diabetic bladder dysfunction is associated with bladder inflammation triggered through hyperglycemia, not polyuria BM Inouye, FM Hughes Jr, H Jin, R Lütolf, KC Potnis, JC Routh, ... Research and reports in urology, 219-225, 2018 | 28 | 2018 |
Cardiac physiologic and genetic predictors of hyperoxia-induced acute lung injury in mice R Howden, HY Cho, L Miller-DeGraff, C Walker, JA Clark, PH Myers, ... American Journal of Respiratory Cell and Molecular Biology 46 (4), 470-478, 2012 | 23 | 2012 |
Intraarterial microdosing: a novel drug development approach, proof-of-concept PET study in rats T Burt, DC Rouse, K Lee, H Wu, AT Layton, TC Hawk, DH Weitzel, ... Journal of Nuclear Medicine 56 (11), 1793-1799, 2015 | 11 | 2015 |
Immediate release of gastrin-releasing peptide mediates delayed radiation-induced pulmonary fibrosis RM Tighe, K Heck, E Soderblom, S Zhou, A Birukova, K Young, D Rouse, ... The American Journal of Pathology 189 (5), 1029-1040, 2019 | 10 | 2019 |
The Influence of Nrf2 on Cardiac Responses to Environmental Stressors R Howden, E Gougian, M Lawrence, S Cividanes, W Gladwell, ... Oxidative Medicine and Cellular Longevity 2013 (1), 901239, 2013 | 9 | 2013 |
Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis. Sci Adv 3: e1602096 L Wang, ER Ko, JJ Gilchrist, KJ Pittman, A Rautanen, M Pirinen, ... | 5 | 2017 |
Evaluation of cold ischemia for preservation of testicular function during partial orchiectomy in the rat model ER McNamara, RJ Madden-Fuentes, JC Routh, D Rouse, JF Madden, ... Journal of pediatric urology 10 (4), 593-597, 2014 | 3 | 2014 |
Evaluating tumor hypoxia radiosensitization via electron paramagnetic resonance oxygen imaging (EPROI) AG Rickard, YM Mowery, A Bassil, DC Rouse, NT Williams, T Charity, ... Molecular Imaging and Biology 26 (3), 435-447, 2024 | 2 | 2024 |
Increased Ca2+ signaling through altered CaV1. 2 L-type Ca2+ channel activity promotes bone formation and prevents estrogen deficiency-induced bone loss. C Cao, Y Ren, AJ Mirando, A Barnett, D Rouse, SH Mun, KH Park-Min, ... JOURNAL OF BONE AND MINERAL RESEARCH 32, S31-S31, 2017 | 2 | 2017 |
Intra-arterial microdosing (IAM), a novel drug development approach, proof of concept in rats T Burt, H Wu, AT Layton, DC Rouse, BB Chin, TC Hawk, DH Weitzel, ... Clinical Therapeutics 37 (8), e40-e41, 2015 | 2 | 2015 |
A Novel Preclinical Murine Model to Monitor Inflammatory Breast Cancer Tumor Growth and Lymphovascular Invasion AG Rickard, DS Sannareddy, A Bennion, P Patel, SJ Sauer, DC Rouse, ... Cancers 15 (8), 2261, 2023 | 1 | 2023 |
The genetic contribution to heart rate and heart rate variability in mice R Howden, E Liu, LE Miller-DeGraff, C Walker, JA Clark, PH Myers, ... Circulation 114 (suppl_18), II_193-II_194, 2006 | 1 | 2006 |