Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection M Côté, J Misasi, T Ren, A Bruchez, K Lee, CM Filone, L Hensley, Q Li, ... Nature 477 (7364), 344-348, 2011 | 820 | 2011 |
MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses A Bruchez, K Sha, J Johnson, L Chen, C Stefani, H McConnell, ... Science 370 (6513), 241-247, 2020 | 89 | 2020 |
Inhibition of Ebola virus infection: identification of Niemann-Pick C1 as the target by optimization of a chemical probe K Lee, T Ren, M Côté, B Gholamreza, J Misasi, A Bruchez, ... ACS medicinal chemistry letters 4 (2), 239-243, 2013 | 36 | 2013 |
Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection N Shukla, SM Roelle, VG Suzart, AM Bruchez, KA Matreyek PLoS pathogens 17 (7), e1009715, 2021 | 27 | 2021 |
Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains SM Roelle, N Shukla, AT Pham, AM Bruchez, KA Matreyek PLoS Biology 20 (7), e3001738, 2022 | 26 | 2022 |
Trimeric receptor-binding domain of SARS-CoV-2 acts as a potent inhibitor of ACE2 receptor-mediated viral entry SC Basavarajappa, AR Liu, A Bruchez, Z Li, VG Suzart, Z Liu, Y Chen, ... Iscience 25 (8), 2022 | 11 | 2022 |
LITAF protects against pore-forming protein–induced cell death by promoting membrane repair C Stefani, AM Bruchez, MG Rosasco, AE Yoshida, KJ Fasano, PF Levan, ... Science Immunology 9 (91), eabq6541, 2024 | 1 | 2024 |
Niemann-Pick C1 is essential for Ebola virus infection and a target of small molecule inhibitors AM Bruchez Harvard University, 2012 | 1 | 2012 |
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage N Shukla, SM Roelle, JC Snell, O DelSignore, AM Bruchez, KA Matreyek Plos Pathogens 20 (5), e1012044, 2024 | | 2024 |
Inhibition of SARS-CoV-2 infection in cellular systems using engineered trimeric receptor-binding domain of spike protein AR Liu, SC Basavarajappa, N Sarkar, A Bruchez, P Ramakrishnan STAR protocols 4 (1), 102127, 2023 | | 2023 |
Multiplex measurements of the impacts of ACE2 sequence and cell surface abundance during SARS-like coronavirus entry N Shukla, N Kamath, S Roelle, A Bruchez, K Matreyek The Journal of Biological Chemistry, 104011, 2023 | | 2023 |
Lentiviral_vector_production_with_PEI K Matreyek, A Bruchez | | 2020 |
Transposon mutagenesis screen identifies host-encoded anti-viral factors AM Bruchez, K Sha, L Chen, A Lacy-Hulbert, L Stuart The Journal of Immunology 196 (1_Supplement), 80.10-80.10, 2016 | | 2016 |