Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor–related protein-mediated transcytosis K Benchenane, V Berezowski, C Ali, M Fernández-Monreal, ... Circulation 111 (17), 2241-2249, 2005 | 224 | 2005 |
Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders L M Valor, J Viosca, J P Lopez-Atalaya, A Barco Current pharmaceutical design 19 (28), 5051-5064, 2013 | 171 | 2013 |
Selective boosting of transcriptional and behavioral responses to drugs of abuse by histone deacetylase inhibition C Sanchis-Segura, JP Lopez-Atalaya, A Barco Neuropsychopharmacology 34 (13), 2642-2654, 2009 | 151 | 2009 |
Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling M Fernández-Monreal, JP López-Atalaya, K Benchenane, M Cacquevel, ... Journal of Biological Chemistry 279 (49), 50850-50856, 2004 | 151 | 2004 |
Equivocal roles of tissue-type plasminogen activator in stroke-induced injury K Benchenane, JP López-Atalaya, M Fernández-Monreal, O Touzani, ... Trends in neurosciences 27 (3), 155-160, 2004 | 143 | 2004 |
CBP is required for environmental enrichment‐induced neurogenesis and cognitive enhancement JP Lopez‐Atalaya, A Ciccarelli, J Viosca, LM Valor, M Jimenez‐Minchan, ... The EMBO journal 30 (20), 4287-4298, 2011 | 122 | 2011 |
Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition JP Lopez-Atalaya, S Ito, LM Valor, E Benito, A Barco Nucleic acids research 41 (17), 8072-8084, 2013 | 112 | 2013 |
Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models TH Hutson, C Kathe, I Palmisano, K Bartholdi, A Hervera, F De Virgiliis, ... Science translational medicine 11 (487), eaaw2064, 2019 | 107 | 2019 |
Loss of Kdm5c causes spurious transcription and prevents the fine-tuning of activity-regulated enhancers in neurons M Scandaglia, JP Lopez-Atalaya, A Medrano-Fernandez, ... Cell reports 21 (1), 47-59, 2017 | 100 | 2017 |
Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity JP Lopez-Atalaya, BD Roussel, D Levrat, J Parcq, O Nicole, Y Hommet, ... Journal of Cerebral Blood Flow & Metabolism 28 (6), 1212-1221, 2008 | 95 | 2008 |
Anti-NR1 N-terminal-domain vaccination unmasks the crucial action of tPA on NMDA-receptor-mediated toxicity and spatial memory K Benchenane, H Castel, M Boulouard, R Bluthé, M Fernandez-Monreal, ... Journal of cell science 120 (4), 578-585, 2007 | 95 | 2007 |
Can changes in histone acetylation contribute to memory formation? JP Lopez-Atalaya, A Barco Trends in genetics 30 (12), 529-539, 2014 | 86 | 2014 |
Tissue‐type plasminogen activator rescues neurones from serum deprivation‐induced apoptosis through a mechanism independent of its proteolytic activity G Liot, BD Roussel, N Lebeurrier, K Benchenane, JP López‐Atalaya, ... Journal of neurochemistry 98 (5), 1458-1464, 2006 | 85 | 2006 |
The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo N Lebeurrier, G Liot, JP Lopez-Atalaya, C Orset, M Fernandez-Monreal, ... Molecular and Cellular Neuroscience 30 (4), 552-558, 2005 | 85 | 2005 |
Genomic landscape of transcriptional and epigenetic dysregulation in early onset polyglutamine disease LM Valor, D Guiretti, JP Lopez-Atalaya, A Barco Journal of Neuroscience 33 (25), 10471-10482, 2013 | 83 | 2013 |
Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming Á Herrero-Navarro, L Puche-Aroca, V Moreno-Juan, ... Science Advances 7 (15), eabe8978, 2021 | 80 | 2021 |
Is tissue-type plasminogen activator a neuromodulator? M Fernández-Monreal, JP López-Atalaya, K Benchenane, F Léveillé, ... Molecular and Cellular Neuroscience 25 (4), 594-601, 2004 | 79 | 2004 |
Recombinant Desmodus rotundus Salivary Plasminogen Activator Crosses the Blood–Brain Barrier Through a Low-Density Lipoprotein Receptor-Related Protein … JP López-Atalaya, BD Roussel, C Ali, E Maubert, KU Petersen, ... Stroke 38 (3), 1036-1043, 2007 | 78 | 2007 |
Histone acetylation deficits in lymphoblastoid cell lines from patients with Rubinstein–Taybi syndrome JP López-Atalaya, C Gervasini, F Mottadelli, S Spena, M Piccione, ... Journal of medical genetics 49 (1), 66-74, 2012 | 77 | 2012 |
Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: differential contribution of p300 and CBP to Rubinstein–Taybi syndrome etiology J Viosca, JP Lopez-Atalaya, R Olivares, R Eckner, A Barco Neurobiology of disease 37 (1), 186-194, 2010 | 70 | 2010 |