| Ribonucleotide reductase requires subunit switching in hypoxia to maintain DNA replication IP Foskolou, C Jorgensen, KB Leszczynska, MM Olcina, H Tarhonskaya, ... Molecular cell 66 (2), 206-220. e9, 2017 | 83 | 2017 |
| An experimentally validated approach to calculate the blood-brain barrier permeability of small molecules Y Wang, E Gallagher, C Jorgensen, EP Troendle, D Hu, PC Searson, ... Scientific reports 9 (1), 6117, 2019 | 46 | 2019 |
| A perspective on structural and computational work on collagen C Domene, C Jorgensen, SW Abbasi Physical Chemistry Chemical Physics 18 (36), 24802-24811, 2016 | 37 | 2016 |
| 2-Oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2 MI Abboud, TE McAllister, IKH Leung, R Chowdhury, C Jorgensen, ... Chemical Communications 54 (25), 3130-3133, 2018 | 30 | 2018 |
| Lateral fenestrations in K+-channels explored using MD simulations C Jorgensen, L Darré, V Oakes, R Torella, D Pryde, C Domene Molecular Pharmaceutics, 2016 | 28 | 2016 |
| Mechanism of molecular oxygen diffusion in a hypoxia-sensing prolyl hydroxylase using multiscale simulation C Domene, C Jorgensen, CJ Schofield Journal of the American Chemical Society 142 (5), 2253-2263, 2020 | 25 | 2020 |
| 13 C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions CT Lohans, DY Wang, C Jorgensen, ST Cahill, IJ Clifton, MA McDonough, ... Organic & biomolecular chemistry 15 (28), 6024-6032, 2017 | 24 | 2017 |
| In silico identification of PAP-1 binding sites in the Kv1. 2 potassium channel C Jorgensen, L Darre, K Vanommeslaeghe, K Omoto, D Pryde, ... Molecular pharmaceutics 12 (4), 1299-1307, 2015 | 24 | 2015 |
| Energetics of ion permeation in an open-activated TRPV1 channel C Jorgensen, S Furini, C Domene Biophysical Journal 111 (6), 1214-1222, 2016 | 23 | 2016 |
| Location and character of volatile general anesthetics binding sites in the transmembrane domain of TRPV1 C Jorgensen, C Domene Molecular pharmaceutics 15 (9), 3920-3930, 2018 | 13 | 2018 |
| Atomistic model of solute transport across the blood–brain barrier C Jorgensen, MB Ulmschneider, PC Searson ACS omega 7 (1), 1100-1112, 2021 | 7 | 2021 |
| The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function IP Foskolou, PP Cunha, E Sánchez-López, EA Minogue, BP Nicolet, ... Cell reports 42 (9), 2023 | 5 | 2023 |
| Quantifying the Binding Interaction between the Hypoxia-Inducible Transcription Factor and the von Hippel–Lindau Suppressor C Domene, C Jorgensen, K Vanommeslaeghe, CJ Schofield, ... Journal of chemical theory and computation 11 (8), 3946-3954, 2015 | 3 | 2015 |
| Modeling Substrate Entry into the P-Glycoprotein Efflux Pump at the Blood–Brain Barrier C Jorgensen, MB Ulmschneider, PC Searson Journal of medicinal chemistry 66 (24), 16615-16627, 2023 | 2 | 2023 |
| Computer Simulations of Membrane Proteins C Jorgensen, V Oakes, C Domene Membrane Organization and Dynamics, 351-374, 2017 | 2 | 2017 |
| A least-squares-fitting procedure for an efficient preclinical ranking of passive transport across the blood–brain barrier endothelium C Jorgensen, EP Troendle, JP Ulmschneider, PC Searson, ... Journal of Computer-Aided Molecular Design 37 (11), 537-549, 2023 | 1 | 2023 |
| Tracking Policy Implications and Impacts of the COVID-19 Pandemic and Related Executive Actions on a Sampling of Foreign-born Early Career Researchers in the US C Jorgensen, MA Astore, F Sancheznieto, S Vedachalam, A Mughal, ... OSF, 2022 | 1 | 2022 |
| Simulations of Active Transport Across the Blood-Brain Barrier C Jorgensen, M Ulmschneider, PC Searson Biophysical Journal 118 (3), 527a, 2020 | 1 | 2020 |
| Towards a multiscale model of P-glycoprotein efflux C Jorgensen, KB Pedersen, MB Ulmschneider, B Schiøtt, PC Searson Biophysical Journal 122 (3), 530a, 2023 | | 2023 |
| An atomistic model of the human stratum corneum: permeation through the long periodicity phase—effect of a pro-penetrant C Jorgensen, F Léonforte, GS Luengo, S Gregoire, B Biatry, PD Olmsted, ... Biophysical Journal 121 (3), 35a, 2022 | | 2022 |
Peter SearsonReynolds Professor of Engineering, Johns Hopkins University在 jhu.edu 的电子邮件经过验证
