Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer P Vallurupalli, A Sekhar, T Yuwen, LE Kay Journal of biomolecular NMR 67, 243-271, 2017 | 141 | 2017 |
Slow conformational exchange and overall rocking motion in ubiquitin protein crystals V Kurauskas, SA Izmailov, ON Rogacheva, A Hessel, I Ayala, ... Nature communications 8 (1), 145, 2017 | 82 | 2017 |
Observing the overall rocking motion of a protein in a crystal P Ma, Y Xue, N Coquelle, JD Haller, T Yuwen, I Ayala, O Mikhailovskii, ... Nature communications 6 (1), 8361, 2015 | 74 | 2015 |
Microsecond time-scale conformational exchange in proteins: using long molecular dynamics trajectory to simulate NMR relaxation dispersion data Y Xue, JM Ward, T Yuwen, IS Podkorytov, NR Skrynnikov Journal of the American Chemical Society 134 (5), 2555-2562, 2012 | 70 | 2012 |
Reversible inhibition of the ClpP protease via an N-terminal conformational switch S Vahidi, ZA Ripstein, M Bonomi, T Yuwen, MF Mabanglo, JB Juravsky, ... Proceedings of the National Academy of Sciences 115 (28), E6447-E6456, 2018 | 57 | 2018 |
The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage J Kitevski-LeBlanc, A Fradet-Turcotte, P Kukic, MD Wilson, G Portella, ... Elife 6, e23872, 2017 | 50 | 2017 |
Investigating the dynamics of destabilized nucleosomes using methyl-TROSY NMR JL Kitevski-LeBlanc, T Yuwen, PN Dyer, J Rudolph, K Luger, LE Kay Journal of the American Chemical Society 140 (14), 4774-4777, 2018 | 46 | 2018 |
Role of electrostatic interactions in binding of peptides and intrinsically disordered proteins to their folded targets. 1. NMR and MD characterization of the complex between … Y Xue, T Yuwen, F Zhu, NR Skrynnikov Biochemistry 53 (41), 6473-6495, 2014 | 46 | 2014 |
Enhancing the Sensitivity of CPMG Relaxation Dispersion to Conformational Exchange Processes by Multiple‐Quantum Spectroscopy T Yuwen, P Vallurupalli, LE Kay Angewandte Chemie International Edition 55 (38), 11490-11494, 2016 | 43 | 2016 |
Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1H‐CEST T Yuwen, A Sekhar, LE Kay Angewandte Chemie International Edition 56 (22), 6122-6125, 2017 | 40 | 2017 |
Dramatic Decrease in CEST Measurement Times Using Multi‐Site Excitation T Yuwen, LE Kay, G Bouvignies ChemPhysChem 19 (14), 1707-1710, 2018 | 39 | 2018 |
Probing Conformational Exchange in Weakly Interacting, Slowly Exchanging Protein Systems via Off-Resonance R1ρ Experiments: Application to Studies of … T Yuwen, JP Brady, LE Kay Journal of the American Chemical Society 140 (6), 2115-2126, 2018 | 39 | 2018 |
A Methyl‐TROSY‐Based 1H Relaxation Dispersion Experiment for Studies of Conformational Exchange in High Molecular Weight Proteins T Yuwen, R Huang, P Vallurupalli, LE Kay Angewandte Chemie 131 (19), 6316-6320, 2019 | 36 | 2019 |
CP-HISQC: a better version of HSQC experiment for intrinsically disordered proteins under physiological conditions T Yuwen, NR Skrynnikov Journal of biomolecular NMR 58, 175-192, 2014 | 36 | 2014 |
Probing slow timescale dynamics in proteins using methyl 1H CEST T Yuwen, R Huang, LE Kay Journal of Biomolecular NMR 68, 215-224, 2017 | 30 | 2017 |
Proton-decoupled CPMG: A better experiment for measuring 15N R2 relaxation in disordered proteins T Yuwen, NR Skrynnikov Journal of Magnetic Resonance 241, 155-169, 2014 | 30 | 2014 |
Exploring methods to expedite the recording of CEST datasets using selective pulse excitation T Yuwen, G Bouvignies, LE Kay Journal of Magnetic Resonance 292, 1-7, 2018 | 27 | 2018 |
Measuring Solvent Hydrogen Exchange Rates by Multifrequency Excitation 15N CEST: Application to Protein Phase Separation T Yuwen, A Bah, JP Brady, F Ferrage, G Bouvignies, LE Kay The Journal of Physical Chemistry B 122 (49), 11206-11217, 2018 | 24 | 2018 |
PDTAC: targeted photodegradation of GPX4 triggers ferroptosis and potent antitumor immunity S Liu, X Zhao, S Shui, B Wang, Y Cui, S Dong, T Yuwen, G Liu Journal of Medicinal Chemistry 65 (18), 12176-12187, 2022 | 23 | 2022 |
Domain cooperativity in multidomain proteins: what can we learn from molecular alignment in anisotropic media? T Yuwen, CB Post, NR Skrynnikov Journal of biomolecular NMR 51, 131-150, 2011 | 21 | 2011 |