Leptin is a growth factor for colonic epithelial cells JCH Hardwick, GR Van Den Brink, GJ Offerhaus, SJH Van Deventer, ... Gastroenterology 121 (1), 79-90, 2001 | 490 | 2001 |
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation GR Van Den Brink, SA Bleuming, JCH Hardwick, BL Schepman, ... Nature genetics 36 (3), 277-282, 2004 | 451 | 2004 |
Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis E Dekker, FJC van den Broek, JB Reitsma, JC Hardwick, GJ Offerhaus, ... Endoscopy 39 (03), 216-221, 2007 | 390 | 2007 |
Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon JCH Hardwick, GR Van Den Brink, SA Bleuming, I Ballester, ... Gastroenterology 126 (1), 111-121, 2004 | 359 | 2004 |
Sonic hedgehog regulates gastric gland morphogenesis in man and mouse GR Van Den Brink, JCH Hardwick, MP Peppelenbosch, ... Gastroenterology 121 (2), 317-328, 2001 | 317 | 2001 |
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Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met J Burggraaf, IMC Kamerling, PB Gordon, L Schrier, ML De Kam, AJ Kales, ... Nature medicine 21 (8), 955-961, 2015 | 287 | 2015 |
One to 2-year surveillance intervals reduce risk of colorectal cancer in families with Lynch syndrome HFA Vasen, M Abdirahman, R Brohet, AMJ Langers, JH Kleibeuker, ... Gastroenterology 138 (7), 2300-2306, 2010 | 274 | 2010 |
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response J Heijmans, JFL de Jeude, BK Koo, SL Rosekrans, MCB Wielenga, ... Cell reports 3 (4), 1128-1139, 2013 | 269 | 2013 |
Bone morphogenetic protein signalling in colorectal cancer JC Hardwick, LL Kodach, GJ Offerhaus, GR Van Den Brink Nature Reviews Cancer 8 (10), 806-812, 2008 | 260 | 2008 |
Sonic hedgehog expression correlates with fundic gland differentiation in the adult gastrointestinal tract GR van den Brink, JCH Hardwick, C Nielsen, C Xu, FJ Ten Kate, ... Gut 51 (5), 628-633, 2002 | 215 | 2002 |
Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells LL Kodach, CL Bos, N Durán, MP Peppelenbosch, CV Ferreira, ... Carcinogenesis 27 (3), 508-516, 2006 | 205 | 2006 |
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Identification of patients with variants in TPMT and dose reduction reduces hematologic events during thiopurine treatment of inflammatory bowel disease MJH Coenen, DJ de Jong, CJ van Marrewijk, LJJ Derijks, SH Vermeulen, ... Gastroenterology 149 (4), 907-917. e7, 2015 | 201 | 2015 |
Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK PW Voorneveld, LL Kodach, RJ Jacobs, N Liv, AC Zonnevylle, ... Gastroenterology 147 (1), 196-208. e13, 2014 | 185 | 2014 |
Effect of aspirin on the Wnt/β-catenin pathway is mediated via protein phosphatase 2A CL Bos, LL Kodach, GR van den Brink, SH Diks, MM van Santen, ... Oncogene 25 (49), 6447-6456, 2006 | 183 | 2006 |
Quality of web-based information on inflammatory bowel diseases S van der Marel, M Duijvestein, JC Hardwick, GR van den Brink, ... Inflammatory bowel diseases 15 (12), 1891-1896, 2009 | 168 | 2009 |
Endoglin expression on cancer-associated fibroblasts regulates invasion and stimulates colorectal cancer metastasis M Paauwe, MJA Schoonderwoerd, RFCP Helderman, TJ Harryvan, ... Clinical Cancer Research 24 (24), 6331-6344, 2018 | 162 | 2018 |
Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic … LL Kodach, RJ Jacobs, PW Voorneveld, ME Wildenberg, HW Verspaget, ... Gut 60 (11), 1544-1553, 2011 | 162 | 2011 |
Blimp1 regulates the transition of neonatal to adult intestinal epithelium V Muncan, J Heijmans, SD Krasinski, NV Büller, ME Wildenberg, ... Nature communications 2 (1), 452, 2011 | 158 | 2011 |