SIRF: Quantitative in situ analysis of protein interactions at DNA replication forks S Roy, JW Luzwick, K Schlacher Journal of Cell Biology 217 (4), 1521-1536, 2018 | 110 | 2018 |
PAXX is an accessory c-NHEJ factor that associates with Ku70 and has overlapping functions with XLF SK Tadi, C Tellier-Lebègue, C Nemoz, P Drevet, S Audebert, S Roy, ... Cell reports 17 (2), 541-555, 2016 | 104 | 2016 |
p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways S Roy, KH Tomaszowski, JW Luzwick, S Park, J Li, M Murphy, ... Elife 7, e31723, 2018 | 89 | 2018 |
XRCC4/XLF interaction is variably required for DNA repair and is not required for ligase IV stimulation S Roy, AJ de Melo, Y Xu, SK Tadi, A Négrel, E Hendrickson, M Modesti, ... Molecular and cellular biology, 2015 | 77 | 2015 |
XRCC4's interaction with XLF is required for coding (but not signal) end joining S Roy, SN Andres, A Vergnes, JA Neal, Y Xu, Y Yu, SP Lees-Miller, ... Nucleic acids research 40 (4), 1684-1694, 2012 | 75 | 2012 |
MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway JW Luzwick, E Dombi, RA Boisvert, S Roy, S Park, S Kunnimalaiyaan, ... Science Advances 7 (51), eabf9441, 2021 | 29 | 2021 |
SIRF: a single-cell assay for in situ protein interaction with nascent DNA replication forks S Roy, K Schlacher Bio-protocol 9 (18), e3377-e3377, 2019 | 17 | 2019 |
RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles MA Longo, S Roy, Y Chen, KH Tomaszowski, AS Arvai, JT Pepper, ... Nature communications 14 (1), 4445, 2023 | 15 | 2023 |
Detection and quantitation of acetylated histones on replicating DNA using in situ proximity ligation assay and Click-It chemistry P Lazarchuk, S Roy, K Schlacher, J Sidorova Protein Acetylation: Methods and Protocols, 29-45, 2019 | 12 | 2019 |
p53 suppresses mutagenic RAD52 and POLθ pathways by orchestrating DNA replication restart homeostasis S Roy, KH Tomaszowski, J Luzwick, S Park, J Li, M Murphy, K Schlacher bioRxiv, 204057, 2017 | 8 | 2017 |
Defining the steps in a multistep mouse model for mammary carcinogenesis HE Varmus, LA Godley, S Roy, ICA Taylor, L Yuschenkoff, YP Shi, ... Cold Spring Harbor symposia on quantitative biology 59, 491-499, 1994 | 8 | 1994 |
GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer Z Ye, S Xu, Y Shi, X Cheng, Y Zhang, S Roy, S Namjoshi, MA Longo, ... Nature communications 15 (1), 2132, 2024 | 6 | 2024 |
Polygenic mutations model the pleiotropic disease of Fanconi Anemia KH Tomaszowski, S Roy, C Keshvani, M Ott, C DiNardo, D Schindler, ... BioRxiv, 2020.09. 01.277038, 2020 | 3 | 2020 |
Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replication stress KH Tomaszowski, S Roy, C Guerrero, P Shukla, C Keshvani, Y Chen, ... Nature communications 14 (1), 1333, 2023 | 2 | 2023 |
GRB2 stabilizes RAD51 at reversed replication forks restricting genomic instability and associated innate immune response Z Ahmed, Z Ye, S Xu, Y Shi, X Cheng, Y Zhang, S Roy, S Namjoshi, ... Cancer Research 84 (6_Supplement), 6404-6404, 2024 | | 2024 |
Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replication stress (vol 15, 2214 , 2024) KH Tomaszowski, S Roy, C Guerrero, P Shukla, C Keshvani, Y Chen, ... NATURE COMMUNICATIONS 15 (1), 2024 | | 2024 |
Author Correction: Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replication stress KH Tomaszowski, S Roy, C Guerrero, P Shukla, C Keshvani, Y Chen, ... nature communications 15 (1), 2214, 2024 | | 2024 |
Diet induced mitochondrial DNA replication instability in Rad51c mutant mice drives sex-bias in anemia of inflammation KH Tomaszowski, Y Chen, S Roy, M Harris, J Zhang, CL Tsai, ... bioRxiv, 2024.09. 21.613572, 2024 | | 2024 |
Mitochondrial DNA Fork Protection by Fanconi Anemia Genes Suppresses cGAS Activation RA Boisvert, S Park, S Roy, S Goffart, D Schindler, K Schlacher | | 2019 |
Abstract LB-263: P53 promotes replication genome stability by epigenetics-enabled MRE11 restart K Schlacher, S Roy, KH Tomaszowski Cancer Research 77 (13_Supplement), LB-263-LB-263, 2017 | | 2017 |