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Jakob Körbelin
Jakob Körbelin
在 uke.de 的电子邮件经过验证
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引用次数
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Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1
H Yousef, CJ Czupalla, D Lee, MB Chen, AN Burke, KA Zera, J Zandstra, ...
Nature medicine 25 (6), 988-1000, 2019
3132019
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
J Wenzel, J Lampe, H Müller-Fielitz, R Schuster, M Zille, K Müller, ...
Nature neuroscience 24 (11), 1522-1533, 2021
2172021
A brain microvasculature endothelial cell‐specific viral vector with the potential to treat neurovascular and neurological diseases
J Körbelin, G Dogbevia, S Michelfelder, DA Ridder, A Hunger, J Wenzel, ...
EMBO molecular medicine 8 (6), 609-625, 2016
1992016
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
AA Ren, DA Snellings, YS Su, CC Hong, M Castro, AT Tang, MR Detter, ...
Nature 594 (7862), 271-276, 2021
1302021
Endothelium-macrophage crosstalk mediates blood-brain barrier dysfunction in hypertension
MM Santisteban, SJ Ahn, D Lane, G Faraco, L Garcia-Bonilla, ...
Hypertension 76 (3), 795-807, 2020
1222020
Vascular endothelial cells: heterogeneity and targeting approaches
JK Hennigs, C Matuszcak, M Trepel, J Körbelin
Cells 10 (10), 2712, 2021
1072021
Pulmonary targeting of adeno-associated viral vectors by next-generation sequencing-guided screening of random capsid displayed peptide libraries
J Körbelin, T Sieber, S Michelfelder, L Lunding, E Spies, A Hunger, ...
Molecular therapy 24 (6), 1050-1061, 2016
1022016
Endothelium-derived semaphorin 3G regulates hippocampal synaptic structure and plasticity via neuropilin-2/PlexinA4
C Tan, NN Lu, CK Wang, DY Chen, NH Sun, H Lyu, J Körbelin, WX Shi, ...
Neuron 101 (5), 920-937. e13, 2019
952019
Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A
AM Nikolakopoulou, Y Wang, Q Ma, AP Sagare, A Montagne, ...
Journal of Experimental Medicine 218 (4), e20202207, 2021
822021
Nanobody-enhanced targeting of AAV gene therapy vectors
AM Eichhoff, K Börner, B Albrecht, W Schäfer, N Baum, F Haag, J Körbelin, ...
Molecular Therapy-Methods & Clinical Development 15, 211-220, 2019
742019
Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo
S Michelfelder, K Varadi, C Raupp, A Hunger, J Körbelin, C Pahrmann, ...
PloS one 6 (8), e23101, 2011
672011
PPARγ-p53-mediated vasculoregenerative program to reverse pulmonary hypertension
JK Hennigs, A Cao, CG Li, M Shi, J Mienert, K Miyagawa, J Körbelin, ...
Circulation research 128 (3), 401-418, 2021
512021
Selective endothelial hyperactivation of oncogenic KRAS induces brain arteriovenous malformations in mice
ES Park, S Kim, S Huang, JY Yoo, J Körbelin, TJ Lee, B Kaur, PK Dash, ...
Annals of Neurology 89 (5), 926-941, 2021
432021
Endothelium-derived semaphorin 3G attenuates ischemic retinopathy by coordinating β-catenin–dependent vascular remodeling
DY Chen, NH Sun, X Chen, JJ Gong, ST Yuan, ZZ Hu, NN Lu, J Körbelin, ...
The Journal of Clinical Investigation 131 (4), 2021
392021
Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors
M Trepel, J Körbelin, E Spies, MB Heckmann, A Hunger, B Fehse, ...
Gene therapy 22 (10), 840-847, 2015
332015
Respiratory muscle dysfunction in long-COVID patients
JK Hennigs, M Huwe, A Hennigs, T Oqueka, M Simon, L Harbaum, ...
Infection 50 (5), 1391-1397, 2022
302022
Gene therapy targeting the blood–brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency
SM Sundaram, A Arrulo Pereira, H Müller-Fielitz, H Köpke, M De Angelis, ...
Brain 145 (12), 4264-4274, 2022
272022
Non-productive angiogenesis disassembles Aß plaque-associated blood vessels
MI Alvarez-Vergara, AE Rosales-Nieves, R March-Diaz, ...
Nature Communications 12 (1), 3098, 2021
272021
Gene therapy decreases seizures in a model of Incontinentia pigmenti
GK Dogbevia, K Töllner, J Körbelin, S Bröer, DA Ridder, H Grasshoff, ...
Annals of Neurology 82 (1), 93-104, 2017
272017
The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension
JK Hennigs, N Lüneburg, A Stage, M Schmitz, J Körbelin, L Harbaum, ...
Purinergic signalling 15, 299-311, 2019
262019
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