| Optimization of the bacterial cytochrome P450 BM3 system for the production of human drug metabolites G Di Nardo, G Gilardi International Journal of Molecular Sciences 13 (12), 15901-15924, 2012 | 130 | 2012 |
| Wild-type CYP102A1 as a biocatalyst: turnover of drugs usually metabolised by human liver enzymes G Di Nardo, A Fantuzzi, A Sideri, P Panicco, C Sassone, C Giunta, ... JBIC Journal of Biological Inorganic Chemistry 12, 313-323, 2007 | 99 | 2007 |
| Structural basis for the functional roles of critical residues in human cytochrome P450 aromatase J Lo, G Di Nardo, J Griswold, C Egbuta, W Jiang, G Gilardi, D Ghosh Biochemistry 52 (34), 5821-5829, 2013 | 94 | 2013 |
| Modulating the coupling efficiency of human cytochrome P450 CYP3A4 at electrode surfaces through protein engineering VR Dodhia, C Sassone, A Fantuzzi, G Di Nardo, SJ Sadeghi, G Gilardi Electrochemistry communications 10 (11), 1744-1747, 2008 | 85 | 2008 |
| Natural compounds as pharmaceuticals: the key role of cytochromes P450 reactivity G Di Nardo, G Gilardi Trends in Biochemical Sciences 45 (6), 511-525, 2020 | 80 | 2020 |
| Protein and electrode engineering for the covalent immobilization of P450 BMP on gold VEV Ferrero, L Andolfi, G Di Nardo, SJ Sadeghi, A Fantuzzi, ... Analytical chemistry 80 (22), 8438-8446, 2008 | 80 | 2008 |
| Site saturation mutagenesis demonstrates a central role for cysteine 298 as proton donor to the catalytic site in CaHydA [FeFe]-hydrogenase S Morra, A Giraudo, G Di Nardo, PW King, G Gilardi, F Valetti PloS one 7 (10), e48400, 2012 | 76 | 2012 |
| Drug–drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4 SJ Sadeghi, S Ferrero, G Di Nardo, G Gilardi Bioelectrochemistry 86, 87-91, 2012 | 61 | 2012 |
| Evidence for an elevated aspartate pKa in the active site of human aromatase G Di Nardo, M Breitner, A Bandino, D Ghosh, GK Jennings, JC Hackett, ... Journal of Biological Chemistry 290 (2), 1186-1196, 2015 | 58 | 2015 |
| Human aromatase: perspectives in biochemistry and biotechnology G Di Nardo, G Gilardi Biotechnology and Applied Biochemistry 60 (1), 92-101, 2013 | 55 | 2013 |
| Catalytic properties of catechol 1, 2-dioxygenase from Acinetobacter radioresistens S13 immobilized on nanosponges G Di Nardo, C Roggero, S Campolongo, F Valetti, F Trotta, G Gilardi Dalton transactions, 6507-6512, 2009 | 54 | 2009 |
| CYP116B5: a new class VII catalytically self‐sufficient cytochrome P450 from Acinetobacter radioresistens that enables growth on alkanes D Minerdi, SJ Sadeghi, G Di Nardo, F Rua, S Castrignanò, P Allegra, ... Molecular microbiology 95 (3), 539-554, 2015 | 51 | 2015 |
| Identification of mutant Asp251Gly/Gln307His of cytochrome P450 BM3 for the generation of metabolites of diclofenac, ibuprofen and tolbutamide GE Tsotsou, A Sideri, A Goyal, G Di Nardo, G Gilardi Chemistry–A European Journal 18 (12), 3582-3588, 2012 | 46 | 2012 |
| Molecular basis for endocrine disruption by pesticides targeting aromatase and estrogen receptor C Zhang, T Schilirò, M Gea, S Bianchi, A Spinello, A Magistrato, G Gilardi, ... International Journal of Environmental Research and Public Health 17 (16), 5664, 2020 | 45 | 2020 |
| Human cytochrome P450 3A4 as a biocatalyst: effects of the engineered linker in modulation of coupling efficiency in 3A4-BMR chimeras D Degregorio, S D'Avino, S Castrignanò, G Di Nardo, SJ Sadeghi, ... Frontiers in Pharmacology 8, 121, 2017 | 41 | 2017 |
| Hydroxylation of non-substituted polycyclic aromatic hydrocarbons by cytochrome P450 BM3 engineered by directed evolution A Sideri, A Goyal, G Di Nardo, GE Tsotsou, G Gilardi Journal of Inorganic Biochemistry 120, 1-7, 2013 | 41 | 2013 |
| Direct spectroscopic evidence for binding of anastrozole to the iron heme of human aromatase. Peering into the mechanism of aromatase inhibition S Maurelli, M Chiesa, E Giamello, G Di Nardo, VEV Ferrero, G Gilardi, ... Chemical Communications 47 (38), 10737-10739, 2011 | 37 | 2011 |
| Self-sufficient class VII cytochromes P450: from full-length structure to synthetic biology applications D Correddu, G Di Nardo, G Gilardi Trends in Biotechnology 39 (11), 1184-1207, 2021 | 36 | 2021 |
| Identification of endocrine disrupting chemicals acting on human aromatase R Baravalle, A Ciaramella, F Baj, G Di Nardo, G Gilardi Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (1), 88-96, 2018 | 34 | 2018 |
| Dynamics and flexibility of human aromatase probed by FTIR and time resolved fluorescence spectroscopy G Di Nardo, M Breitner, SJ Sadeghi, S Castrignano, G Mei, A Di Venere, ... PLoS One 8 (12), e82118, 2013 | 34 | 2013 |
