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Multi-stage differentiation defines melanoma subtypes with differential vulnerability to drug-induced iron-dependent oxidative stress J Tsoi, L Robert, K Paraiso, C Galvan, KM Sheu, J Lay, DJL Wong, M Atefi, ... Cancer cell 33 (5), 890-904. e5, 2018 | 672 | 2018 |
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma J Müller, O Krijgsman, J Tsoi, L Robert, W Hugo, C Song, X Kong, ... Nature communications 5 (1), 5712, 2014 | 645 | 2014 |
Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAFV600E melanoma S Hu-Lieskovan, S Mok, B Homet Moreno, J Tsoi, L Robert, L Goedert, ... Science translational medicine 7 (279), 279ra41-279ra41, 2015 | 593 | 2015 |
Genetic mechanisms of immune evasion in colorectal cancer CS Grasso, M Giannakis, DK Wells, T Hamada, XJ Mu, M Quist, JA Nowak, ... Cancer discovery 8 (6), 730-749, 2018 | 424 | 2018 |
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Conserved interferon-γ signaling drives clinical response to immune checkpoint blockade therapy in melanoma CS Grasso, J Tsoi, M Onyshchenko, G Abril-Rodriguez, ... Cancer cell 38 (4), 500-515. e3, 2020 | 275 | 2020 |
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance Y Su, W Wei, L Robert, M Xue, J Tsoi, A Garcia-Diaz, B Homet Moreno, ... Proceedings of the National Academy of Sciences 114 (52), 13679-13684, 2017 | 222 | 2017 |
Response to programmed cell death-1 blockade in a murine melanoma syngeneic model requires costimulation, CD4, and CD8 T cells B Homet Moreno, JM Zaretsky, A Garcia-Diaz, J Tsoi, G Parisi, L Robert, ... Cancer immunology research 4 (10), 845-857, 2016 | 155 | 2016 |
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Antitumor activity of the ERK inhibitor SCH722984 against BRAF mutant, NRAS mutant and wild-type melanoma DJL Wong, L Robert, MS Atefi, A Lassen, G Avarappatt, M Cerniglia, ... Molecular cancer 13, 1-15, 2014 | 126 | 2014 |
Overcoming genetically based resistance mechanisms to PD-1 blockade DY Torrejon, G Abril-Rodriguez, AS Champhekar, J Tsoi, KM Campbell, ... Cancer Discovery 10 (8), 1140-1157, 2020 | 111 | 2020 |
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A Pilot Trial of the Combination of Transgenic NY-ESO-1–reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination with or without Ipilimumab TS Nowicki, B Berent-Maoz, G Cheung-Lau, RR Huang, X Wang, J Tsoi, ... Clinical Cancer Research 25 (7), 2096-2108, 2019 | 84 | 2019 |
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Melanoma dedifferentiation induced by IFN-γ epigenetic remodeling in response to anti–PD-1 therapy YJ Kim, KM Sheu, J Tsoi, G Abril-Rodriguez, E Medina, CS Grasso, ... The Journal of clinical investigation 131 (12), 2021 | 42 | 2021 |
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