Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche AL Boyd, JC Reid, KR Salci, L Aslostovar, YD Benoit, Z Shapovalova, ... Nature cell biology 19 (11), 1336-1347, 2017 | 193 | 2017 |
Identification of chemotherapy-induced leukemic-regenerating cells reveals a transient vulnerability of human AML recurrence AL Boyd, L Aslostovar, J Reid, W Ye, B Tanasijevic, DP Porras, ... Cancer cell 34 (3), 483-498. e5, 2018 | 173 | 2018 |
Regional localization within the bone marrow influences the functional capacity of human HSCs B Guezguez, CJV Campbell, AL Boyd, F Karanu, FL Casado, C Di Cresce, ... Cell stem cell 13 (2), 175-189, 2013 | 133 | 2013 |
Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs AL Boyd, CJV Campbell, CI Hopkins, A Fiebig-Comyn, J Russell, ... The Journal of experimental medicine 211 (10), 1925, 2014 | 96 | 2014 |
Molecular pathways: Epigenetic modulation of Wnt–glycogen synthase kinase-3 signaling to target human cancer stem cells YD Benoit, B Guezguez, AL Boyd, M Bhatia Clinical Cancer Research 20 (21), 5372-5378, 2014 | 49 | 2014 |
Sam68 allows selective targeting of human cancer stem cells YD Benoit, RR Mitchell, RM Risueño, L Orlando, B Tanasijevic, AL Boyd, ... Cell Chemical Biology 24 (7), 833-844. e9, 2017 | 46 | 2017 |
A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia L Aslostovar, AL Boyd, M Almakadi, TJ Collins, DP Leong, RG Tirona, ... Blood advances 2 (15), 1935-1945, 2018 | 44 | 2018 |
CXCL12/CXCR4 signaling enhances human PSC-derived hematopoietic progenitor function and overcomes early in vivo transplantation failure JC Reid, B Tanasijevic, D Golubeva, AL Boyd, DP Porras, TJ Collins, ... Stem Cell Reports 10 (5), 1625-1641, 2018 | 35 | 2018 |
Nonhematopoietic cells represent a more rational target of in vivo hedgehog signaling affecting normal or acute myeloid leukemia progenitors AL Boyd, KR Salci, Z Shapovalova, BAS McIntyre, M Bhatia Experimental hematology 41 (10), 858-869. e4, 2013 | 27 | 2013 |
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics YD Benoit, RR Mitchell, W Wang, L Orlando, AL Boyd, B Tanasijevic, ... Cell chemical biology 28 (10), 1394-1406. e10, 2021 | 18 | 2021 |
Phosphorylation state of the histone variant H2A. X controls human stem and progenitor cell fate decisions L Orlando, B Tanasijevic, M Nakanishi, JC Reid, JL García-Rodríguez, ... Cell Reports 34 (10), 2021 | 15 | 2021 |
Bone marrow localization and functional properties of human hematopoietic stem cells AL Boyd, M Bhatia Current opinion in hematology 21 (4), 249-255, 2014 | 13 | 2014 |
Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients L Aslostovar, AL Boyd, YD Benoit, J Di Lu, JLG Rodriguez, M Nakanishi, ... Cell Reports Medicine 2 (2), 2021 | 9 | 2021 |
Chemical genomics reveals targetable programs of human cancers rooted in pluripotency L Orlando, YD Benoit, JC Reid, M Nakanishi, AL Boyd, ... Cell chemical biology 30 (7), 780-794. e8, 2023 | 6 | 2023 |
Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients JC Reid, D Golubeva, AL Boyd, CG Hollands, C Henly, L Orlando, ... Cell Reports 34 (11), 2021 | 6 | 2021 |
Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia AL Boyd, J Lu, CG Hollands, L Alsostovar, S Murali, JC Reid, W Ye, ... Cell Reports Medicine 4 (7), 2023 | 5 | 2023 |
Reprogramming of acute myeloid leukemia patients cells: harboring cancer mutations requires targeting of AML hierarchy D Golubeva, DP Porras, M Doyle, JC Reid, B Tanasijevic, AL Boyd, ... Stem Cells Translational Medicine 12 (6), 334-354, 2023 | 3 | 2023 |
Playing musical chairs with bone marrow transplantation to eliminate leukemia stem cells AL Boyd, M Bhatia Molecular & Cellular Oncology 2 (3), e988480, 2015 | 2 | 2015 |
Identification of cells of leukemic stem cell origin with non-canonical regenerative properties CG Hollands, AL Boyd, X Zhao, JC Reid, C Henly, A ElRafie, D Boylan, ... Cell Reports Medicine 5 (4), 2024 | 1 | 2024 |
Challenges in Cell Fate Acquisition to Scid-Repopulating Activity from Hemogenic Endothelium of hiPSCs Derived from AML Patients Using Forced Transcription Factor Expression DP Porras, JC Reid, B Tanasijevic, D Golubeva, AL Boyd, M Bhatia Cells 11 (12), 1915, 2022 | | 2022 |