TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ... Nature 603 (7899), 131-137, 2022 | 283 | 2022 |
The role of hnRNPs in frontotemporal dementia and amyotrophic lateral sclerosis A Bampton, LM Gittings, P Fratta, T Lashley, A Gatt Acta Neuropathologica 140 (5), 599-623, 2020 | 105 | 2020 |
Dementia in Parkinson's disease is associated with enhanced mitochondrial complex I deficiency AP Gatt, OF Duncan, J Attems, PT Francis, CG Ballard, JM Bateman Movement Disorders 31 (3), 352-359, 2016 | 90 | 2016 |
Concerted control of gliogenesis by InR/TOR and FGF signalling in the Drosophila post-embryonic brain A Avet-Rochex, AK Kaul, AP Gatt, H McNeill, JM Bateman Development 139 (15), 2763-2772, 2012 | 77 | 2012 |
Mitochondrial retrograde signaling regulates neuronal function U Cagin, OF Duncan, AP Gatt, MS Dionne, ST Sweeney, JM Bateman Proceedings of the National Academy of Sciences 112 (44), E6000-E6009, 2015 | 66 | 2015 |
Drug repurposing for Alzheimer’s disease based on transcriptional profiling of human iPSC-derived cortical neurons G Williams, A Gatt, E Clarke, J Corcoran, P Doherty, D Chambers, ... Translational psychiatry 9 (1), 220, 2019 | 59 | 2019 |
Association of a polymorphism in mitochondrial transcription factor A (TFAM) with Parkinson's disease dementia but not dementia with Lewy bodies AP Gatt, EL Jones, PT Francis, C Ballard, JM Bateman Neuroscience letters 557, 177-180, 2013 | 45 | 2013 |
HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing A Bampton, A Gatt, J Humphrey, S Cappelli, D Bhattacharya, S Foti, ... Acta neuropathologica 142, 609-627, 2021 | 38 | 2021 |
Expression of neurogenic markers in Alzheimer's disease: a systematic review and metatranscriptional analysis A Gatt, H Lee, G Williams, S Thuret, C Ballard Neurobiology of Aging 76, 166-180, 2019 | 31 | 2019 |
Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, FCY Lee, ... BioRxiv, 2021.04. 02.438170, 2021 | 30 | 2021 |
Importance of proactive treatment of depression in Lewy body dementias: the impact on hippocampal neurogenesis and cognition in a post-mortem study A Gatt, A Ekonomou, A Somani, S Thuret, D Howlett, A Corbett, ... Dementia and geriatric cognitive disorders 44 (5-6), 283-293, 2018 | 24 | 2018 |
Consortium AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ... NA, Newcombe, J., Gustavsson, EK, Seddighi, S.,… Maggin, D, 2022 | 23 | 2022 |
HnRNP K mislocalisation in neurons of the dentate nucleus is a novel neuropathological feature of neurodegenerative disease and ageing R Sidhu, A Gatt, P Fratta, T Lashley, A Bampton Neuropathology and Applied Neurobiology 48 (4), e12793, 2022 | 16 | 2022 |
Aberrant axon initial segment plasticity and intrinsic excitability of ALS hiPSC motor neurons P Harley, C Kerins, A Gatt, G Neves, F Riccio, CB Machado, ... Cell Reports 42 (12), 2023 | 8 | 2023 |
Alzheimer’s disease progression in the 5× FAD mouse captured with a multiplex gene expression array A Gatt, DR Whitfield, C Ballard, P Doherty, G Williams Journal of Alzheimer's Disease 72 (4), 1177-1191, 2019 | 6 | 2019 |
Identifying Novel Candidates for Re-Purposing as Potential Therapeutic Agents for Alzheimer’s disease C Ballard, B Creese, A Gatt, P Doherty, PT Francis, D Whitfield, A Corbett, ... bioRxiv, 622308, 2019 | 4 | 2019 |
Advances in the Understanding of Frontotemporal Dementia R Bandopadhyay, A Gatt, T Lashley Cells 12 (5), 781, 2023 | 2 | 2023 |
Interaction of amisulpride with GLUT1 at the blood-brain barrier. Relevance to Alzheimer’s disease ST Boyanova, E Lloyd-Morris, C Corpe, KM Rahman, DB Farag, LK Page, ... Plos one 18 (10), e0286278, 2023 | 1 | 2023 |
HnRNP Pathologies in Frontotemporal Lobar Degeneration X Jiang, A Gatt, T Lashley Cells 12 (12), 1633, 2023 | 1 | 2023 |
Heightened sensitivity of people with Alzheimer’s disease to the side effects of antipsychotic drug amisulpride may be mediated through an interaction with glucose transporter … S Boyanova, H Wang, AL Fleckney, A Gatt, DB Farag, KM Rahman, ... Alzheimer's & Dementia 16, e047395, 2020 | 1 | 2020 |