Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension CD Cox, C Bae, L Ziegler, S Hartley, V Nikolova-Krstevski, PR Rohde, ... Nature communications 7 (1), 10366, 2016 | 490 | 2016 |
The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4 C Bae, F Sachs, PA Gottlieb Biochemistry 50 (29), 6295-6300, 2011 | 486 | 2011 |
Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers TM Suchyna, SE Tape, RE Koeppe, OS Andersen, F Sachs, PA Gottlieb Nature 430 (6996), 235-240, 2004 | 361 | 2004 |
Effects of stretch‐activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse EW Yeung, NP Whitehead, TM Suchyna, PA Gottlieb, F Sachs, DG Allen The Journal of physiology 562 (2), 367-380, 2005 | 342 | 2005 |
Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1 C Bae, R Gnanasambandam, C Nicolai, F Sachs, PA Gottlieb Proceedings of the National Academy of Sciences 110 (12), E1162-E1168, 2013 | 315 | 2013 |
Revisiting TRPC1 and TRPC6 mechanosensitivity P Gottlieb, J Folgering, R Maroto, A Raso, TG Wood, A Kurosky, ... Pflügers Archiv-European Journal of Physiology 455, 1097-1103, 2008 | 296 | 2008 |
On-chip microfluidic biosensor for bacterial detection and identification DA Boehm, PA Gottlieb, SZ Hua Sensors and Actuators B: Chemical 126 (2), 508-514, 2007 | 229 | 2007 |
Gating the mechanical channel Piezo1: a comparison between whole-cell and patch recording PA Gottlieb, C Bae, F Sachs Channels 6 (4), 282-289, 2012 | 217 | 2012 |
Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: history, properties, mechanisms and pharmacology CL Bowman, PA Gottlieb, TM Suchyna, YK Murphy, F Sachs Toxicon 49 (2), 249-270, 2007 | 210 | 2007 |
Ionic selectivity and permeation properties of human PIEZO1 channels R Gnanasambandam, C Bae, PA Gottlieb, F Sachs PloS one 10 (5), e0125503, 2015 | 172 | 2015 |
Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces F Wang, K Knutson, C Alcaino, DR Linden, SJ Gibbons, P Kashyap, ... The Journal of physiology 595 (1), 79-91, 2017 | 165 | 2017 |
Piezo1: properties of a cation selective mechanical channel PA Gottlieb, F Sachs Channels 6 (4), 214-219, 2012 | 145 | 2012 |
Ca2+ influx through mechanosensitive channels inhibits neurite outgrowth in opposition to other influx pathways and release from intracellular stores BT Jacques-Fricke, Y Seow, PA Gottlieb, F Sachs, TM Gomez Journal of Neuroscience 26 (21), 5656-5664, 2006 | 135 | 2006 |
Tuftsin, Thr-Lys-Pro-Arg: anatomy of an immunologically active peptide M Fridkin, P Gottlieb Immunologically Active Peptides, 73-97, 1981 | 124 | 1981 |
Mechanosensitive TRPC1 channels promote calpain proteolysis of talin to regulate spinal axon outgrowth PC Kerstein, BT Jacques-Fricke, J Rengifo, BJ Mogen, JC Williams, ... Journal of Neuroscience 33 (1), 273-285, 2013 | 119 | 2013 |
Solution structure of peptide toxins that block mechanosensitive ion channels RE Oswald, TM Suchyna, R McFeeters, P Gottlieb, F Sachs Journal of Biological Chemistry 277 (37), 34443-34450, 2002 | 117 | 2002 |
Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters P Ridone, E Pandzic, M Vassalli, CD Cox, A Macmillan, PA Gottlieb, ... The Journal of general physiology 152 (8), 2020 | 112 | 2020 |
cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels KL Ostrow, A Mammoser, T Suchyna, F Sachs, R Oswald, S Kubo, ... Toxicon 42 (3), 263-274, 2003 | 93 | 2003 |
Equilibrium, kinetic, and footprinting studies of the Tus-Ter protein-DNA interaction. PA Gottlieb, S Wu, X Zhang, M Tecklenburg, P Kuempel, TM Hill Journal of Biological Chemistry 267 (11), 7434-7443, 1992 | 90 | 1992 |
The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms J Kockskämper, D von Lewinski, M Khafaga, A Elgner, M Grimm, ... Progress in biophysics and molecular biology 97 (2-3), 250-267, 2008 | 88 | 2008 |