Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism R Limbocker, B Mannini, FS Ruggeri, R Cascella, CK Xu, M Perni, S Chia, ... Communications biology 3 (1), 435, 2020 | 57 | 2020 |
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers R Limbocker, R Staats, S Chia, FS Ruggeri, B Mannini, CK Xu, M Perni, ... Frontiers in Neuroscience 15, 680026, 2021 | 47 | 2021 |
Therapeutic strategies to reduce the toxicity of misfolded protein oligomers RP Kreiser, AK Wright, NR Block, JE Hollows, LT Nguyen, K LeForte, ... International journal of molecular sciences 21 (22), 8651, 2020 | 32 | 2020 |
Rationally designed antibodies as research tools to study the structure–toxicity relationship of amyloid-β oligomers R Limbocker, B Mannini, R Cataldi, S Chhangur, AK Wright, RP Kreiser, ... International Journal of Molecular Sciences 21 (12), 4542, 2020 | 16 | 2020 |
A brain-permeable aminosterol regulates cell membranes to mitigate the toxicity of diverse pore-forming agents RP Kreiser, AK Wright, LR Sasser, DJ Rinauro, JM Gabriel, CM Hsu, ... ACS chemical neuroscience 13 (8), 1219-1231, 2022 | 9 | 2022 |
Utilization of standardized college entrance metrics to predict undergraduate student success in chemistry RP Kreiser, AK Wright, TL McKenzie, JA Albright, ED Mowles, JE Hollows, ... Journal of Chemical Education 99 (4), 1725-1733, 2022 | 5 | 2022 |
Attenuating the toxicity of protein misfolded oligomers using aminosterols LR Sasser, AK Wright, RP Kreiser, L Nguyen, R Limbocker Biophysical Journal 121 (3), 352a, 2022 | | 2022 |
Key membrane lipids can alter the resiliency of neuronal cells to protein misfolded oligomer toxicity RP Kreiser, AK Wright, LR Sasser, TL McKenzie, LT Nguyen, R Limbocker Biophysical Journal 121 (3), 79a, 2022 | | 2022 |
Small molecule and antibody mediated inhibition of the aggregation of a tau fragment implicit in Alzheimer's disease TL McKenzie, RP Kreiser, RA Limbocker, DJ Rinauro, M Vendruscolo Biophysical Journal 121 (3), 189a, 2022 | | 2022 |
Protecting the cell mebrane against pore-forming agents via a brain-permeable aminosterol AK Wright, RP Kreiser, LR Sasser, LT Nguyen, R Limbocker Biophysical Journal 121 (3), 189a, 2022 | | 2022 |
Modulators of the plasma membrane protect cells from diverse toxic agents, ranging from protein misfolded oligomers to pore forming agents R Limbocker, RP Kreiser, LR Sasser, AK Wright, DJ Rinauro, ... Biophysical Journal 121 (3), 350a, 2022 | | 2022 |
Investigation of Molecular Countermeasures to Modulate the Populations and Toxicity of Aβ42 Oligomers AK Wright, RP Kreiser, LT Nguyen, JE Hollows, R Limbocker Biophysical Journal 120 (3), 202a, 2021 | | 2021 |
Therapeutics Against Protein Misfolded Oligomers in Neurodegenerative Diseases R Limbocker, A Wright, RP Kreiser, B Mannini, M Vendruscolo Biophysical Journal 120 (3), 286a, 2021 | | 2021 |
Cell Membrane Properties can Mediate the Toxicity of Protein Misfolded Oligomers and Folded Toxins RP Kreiser, AK Wright, LT Nguyen, JE Hollows, R Limbocker Biophysical Journal 120 (3), 308a, 2021 | | 2021 |