Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle E De Fabiani, N Mitro, F Gilardi, D Caruso, G Galli, M Crestani Journal of Biological Chemistry 278 (40), 39124-39132, 2003 | 254 | 2003 |
Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue A Galmozzi, N Mitro, A Ferrari, E Gers, F Gilardi, C Godio, G Cermenati, ... diabetes 62 (3), 732-742, 2013 | 251 | 2013 |
The negative effects of bile acids and tumor necrosis factor-α on the transcription of cholesterol 7α-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel … E De Fabiani, N Mitro, AC Anzulovich, A Pinelli, G Galli, M Crestani Journal of Biological Chemistry 276 (33), 30708-30716, 2001 | 231 | 2001 |
Transcriptional activation of the cholesterol 7α-hydroxylase gene (CYP7A) by nuclear hormone receptors M Crestani, A Sadeghpour, D Stroup, G Galli, JYL Chiang Journal of lipid research 39 (11), 2192-2200, 1998 | 194 | 1998 |
Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation M Dell'Agli, R Fagnani, N Mitro, S Scurati, M Masciadri, L Mussoni, ... Journal of agricultural and food chemistry 54 (9), 3259-3264, 2006 | 152 | 2006 |
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor γ ligand-binding domain in the complex with two … G Pochetti, C Godio, N Mitro, D Caruso, A Galmozzi, S Scurati, F Loiodice, ... Journal of Biological Chemistry 282 (23), 17314-17324, 2007 | 141 | 2007 |
Lipids in the nervous system: from biochemistry and molecular biology to patho-physiology G Cermenati, N Mitro, M Audano, RC Melcangi, M Crestani, E De Fabiani, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 131 | 2015 |
Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic … R Montanari, F Saccoccia, E Scotti, M Crestani, C Godio, F Gilardi, ... Journal of medicinal chemistry 51 (24), 7768-7776, 2008 | 128 | 2008 |
Identification of a bile acid response element in the cholesterol 7 alpha-hydroxylase gene CYP7A D Stroup, M Crestani, JY Chiang American Journal of Physiology-Gastrointestinal and Liver Physiology 273 (2 …, 1997 | 122 | 1997 |
An essential role for liver ERα in coupling hepatic metabolism to the reproductive cycle S Della Torre, N Mitro, R Fontana, M Gomaraschi, E Favari, C Recordati, ... Cell reports 15 (2), 360-371, 2016 | 119 | 2016 |
Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation G Cermenati, F Abbiati, S Cermenati, E Brioschi, A Volonterio, G Cavaletti, ... Journal of lipid research 53 (2), 300-310, 2012 | 119 | 2012 |
Transcriptional regulation of the human cholesterol 7 alpha-hydroxylase gene (CYP7A) in HepG2 cells DP Wang, D Stroup, M Marrapodi, M Crestani, G Galli, JY Chiang Journal of lipid research 37 (9), 1831-1841, 1996 | 114 | 1996 |
Hormonal regulation of the cholesterol 7 alpha-hydroxylase gene (CYP7) M Crestani, D Stroup, JY Chiang Journal of lipid research 36 (11), 2419-2432, 1995 | 110 | 1995 |
Ketogenic diet: a new light shining on old but gold biochemistry R Longo, C Peri, D Cricrì, L Coppi, D Caruso, N Mitro, E De Fabiani, ... Nutrients 11 (10), 2497, 2019 | 96 | 2019 |
Olive oil phenols modulate the expression of metalloproteinase 9 in THP-1 cells by acting on nuclear factor-κB signaling M Dell’Agli, R Fagnani, GV Galli, O Maschi, F Gilardi, S Bellosta, ... Journal of agricultural and food chemistry 58 (4), 2246-2252, 2010 | 94 | 2010 |
The pharmacological exploitation of cholesterol 7α-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol F Gilardi, N Mitro, C Godio, E Scotti, D Caruso, M Crestani, E De Fabiani Pharmacology & therapeutics 116 (3), 449-472, 2007 | 89 | 2007 |
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning A Ferrari, R Longo, E Fiorino, R Silva, N Mitro, G Cermenati, F Gilardi, ... Nature communications 8 (1), 93, 2017 | 82 | 2017 |
LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport M Crestani, E De Fabiani, D Caruso, N Mitro, F Gilardi, AB Vigil Chacon, ... Biochemical Society Transactions 32 (1), 92-96, 2004 | 76 | 2004 |
Orphan receptors chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and retinoid X receptor (RXR) activate and bind the rat cholesterol 7α-hydroxylase gene … D Stroup, M Crestani, JYL Chiang Journal of Biological Chemistry 272 (15), 9833-9839, 1997 | 75 | 1997 |
Insights in the regulation of cholesterol 7α‐hydroxylase gene reveal a target for modulating bile acid synthesis N Mitro, C Godio, E De Fabiani, E Scotti, A Galmozzi, F Gilardi, D Caruso, ... Hepatology 46 (3), 885-897, 2007 | 74 | 2007 |