The C‐terminal domain of biotin protein ligase from E. coli is required for catalytic activity A Chapman‐Smith, TD Mulhern, F Whelan, JE Cronan Jr, JC Wallace Protein Science 10 (12), 2608-2617, 2001 | 95 | 2001 |
The pleiotropy of dioxin toxicity—Xenobiotic misappropriation of the aryl hydrocarbon receptor's alternative physiological roles SGB Furness, F Whelan Pharmacology & therapeutics 124 (3), 336-353, 2009 | 72 | 2009 |
Investigating the structural compaction of biomolecules upon transition to the gas-phase using ESI-TWIMS-MS PWA Devine, HC Fisher, AN Calabrese, F Whelan, DR Higazi, JR Potts, ... Journal of the American Society for Mass Spectrometry 28 (9), 1855-1862, 2017 | 62 | 2017 |
Cooperative folding of intrinsically disordered domains drives assembly of a strong elongated protein DT Gruszka, F Whelan, OE Farrance, HKH Fung, E Paci, CM Jeffries, ... Nature communications 6 (1), 7271, 2015 | 60 | 2015 |
Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases RT Byrne, HT Jenkins, DT Peters, F Whelan, J Stowell, N Aziz, P Kasatsky, ... Proceedings of the National Academy of Sciences 112 (19), 6033-6037, 2015 | 42 | 2015 |
Disorder drives cooperative folding in a multidomain protein DT Gruszka, CATF Mendonça, E Paci, F Whelan, J Hawkhead, JR Potts, ... Proceedings of the National Academy of Sciences 113 (42), 11841-11846, 2016 | 26 | 2016 |
Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator F Whelan, N Hao, SGB Furness, ML Whitelaw, A Chapman-Smith Molecular Pharmacology 77 (6), 1037-1046, 2010 | 24 | 2010 |
A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding F Whelan, JA Stead, AV Shkumatov, DI Svergun, CM Sanders, AA Antson Nucleic acids research 40 (5), 2271-2283, 2012 | 21 | 2012 |
S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA RT Byrne, F Whelan, P Aller, LE Bird, A Dowle, CMC Lobley, Y Reddivari, ... Acta Crystallographica Section D: Biological Crystallography 69 (6), 1090-1098, 2013 | 18 | 2013 |
Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection F Whelan, A Lafita, SC Griffiths, REM Cooper, JL Whittingham, ... Proceedings of the National Academy of Sciences 116 (52), 26540-26548, 2019 | 17 | 2019 |
From bacterial to human dihydrouridine synthase: automated structure determination F Whelan, HT Jenkins, SC Griffiths, RT Byrne, EJ Dodson, AA Antson Acta Crystallographica Section D: Biological Crystallography 71 (7), 1564-1571, 2015 | 16 | 2015 |
Periscope Proteins are variable-length regulators of bacterial cell surface interactions F Whelan, A Lafita, J Gilburt, C Dégut, SC Griffiths, HT Jenkins, ... Proceedings of the National Academy of Sciences 118 (23), e2101349118, 2021 | 15 | 2021 |
Structural basis for DNA strand separation by a hexameric replicative helicase Y Chaban, JA Stead, K Ryzhenkova, F Whelan, EP Lamber, A Antson, ... Nucleic Acids Research 43 (17), 8551-8563, 2015 | 15 | 2015 |
Sulfonation and Phosphorylation of Regions of the Dioxin Receptor Susceptible to Methionine Modifications* S KA Dave, F Whelan, C Bindloss, SGB Furness, A Chapman-Smith, ... Molecular & Cellular Proteomics 8 (4), 706-719, 2009 | 13 | 2009 |
Efficient O-demethylation of lignin monoaromatics using the peroxygenase activity of cytochrome P450 enzymes AC Harlington, KE Shearwin, SG Bell, F Whelan Chemical Communications 58 (96), 13321-13324, 2022 | 12 | 2022 |
Two repetitive, biofilm-forming proteins from Staphylococci: from disorder to extension F Whelan, JR Potts Biochemical Society Transactions 43 (5), 861-866, 2015 | 9 | 2015 |
Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of human dihydrouridine synthase S Griffiths, RT Byrne, AA Antson, F Whelan Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 7 | 2012 |
Rational design and self-assembly of coiled-coil linked SasG protein fibrils L Jasaitis, CD Silver, AE Rawlings, DT Peters, F Whelan, L Regan, ... ACS Synthetic Biology 9 (7), 1599-1607, 2020 | 5 | 2020 |
Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface LC Clark, KE Atkin, F Whelan, AS Brentnall, G Harris, AM Towell, ... Journal of Biological Chemistry 299 (3), 2023 | 4 | 2023 |
The long and the short of Periscope Proteins F Whelan Biochemical Society Transactions 50 (5), 1293-1302, 2022 | 1 | 2022 |