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Holger Winkels
Holger Winkels
Associate Professor, University of Cologne
在 uk-koeln.de 的电子邮件经过验证 - 首页
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Single-cell RNA-seq reveals the transcriptional landscape and heterogeneity of aortic macrophages in murine atherosclerosis
C Cochain, E Vafadarnejad, P Arampatzi, J Pelisek, H Winkels, K Ley, ...
Circulation research 122 (12), 1661-1674, 2018
7052018
Atlas of the immune cell repertoire in mouse atherosclerosis defined by single-cell RNA-sequencing and mass cytometry
H Winkels, E Ehinger, M Vassallo, K Buscher, HQ Dinh, K Kobiyama, ...
Circulation research 122 (12), 1675-1688, 2018
4572018
T cell subsets and functions in atherosclerosis
R Saigusa, H Winkels, K Ley
Nature Reviews Cardiology 17 (7), 387-401, 2020
4192020
Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas
A Zernecke, H Winkels, C Cochain, JW Williams, D Wolf, O Soehnlein, ...
Circulation research 127 (3), 402-426, 2020
2542020
Regulatory CD4+ T Cells Recognize Major Histocompatibility Complex Class II Molecule–Restricted Peptide Epitopes of Apolipoprotein B
T Kimura, K Kobiyama, H Winkels, K Tse, J Miller, M Vassallo, D Wolf, ...
Circulation 138 (11), 1130-1143, 2018
1462018
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance
A Chatzigeorgiou, T Seijkens, B Zarzycka, D Engel, M Poggi, ...
Proceedings of the National Academy of Sciences 111 (7), 2686-2691, 2014
1402014
Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100–Reactive CD4+ T-Regulatory Cells
D Wolf, T Gerhardt, H Winkels, NA Michel, AB Pramod, Y Ghosheh, ...
Circulation 142 (13), 1279-1293, 2020
1232020
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential
C Spitz, H Winkels, C Bürger, C Weber, E Lutgens, GK Hansson, ...
Cellular and molecular life sciences 73, 901-922, 2016
1232016
Platelet CD40 exacerbates atherosclerosis by transcellular activation of endothelial cells and leukocytes
N Gerdes, T Seijkens, D Lievens, MJE Kuijpers, H Winkels, D Projahn, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (3), 482-490, 2016
1232016
Single cell RNA sequencing in atherosclerosis research
JW Williams, H Winkels, CP Durant, K Zaitsev, Y Ghosheh, K Ley
Circulation research 126 (9), 1112-1126, 2020
1102020
Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production
M Orecchioni, K Kobiyama, H Winkels, Y Ghosheh, S McArdle, Z Mikulski, ...
Science 375 (6577), 214-221, 2022
1072022
A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense
D Wolf, N Anto-Michel, H Blankenbach, A Wiedemann, K Buscher, ...
Nature communications 9 (1), 525, 2018
972018
Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis
D Lievens, KL Habets, AK Robertson, Y Laouar, H Winkels, ...
European heart journal 34 (48), 3717-3727, 2013
782013
IL-1 family cytokines in cardiovascular disease
S Pfeiler, H Winkels, M Kelm, N Gerdes
Cytokine 122, 154215, 2019
712019
Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain
JM Navia-Pelaez, SH Choi, L dos Santos Aggum Capettini, Y Xia, ...
Journal of Experimental Medicine 218 (7), e20202059, 2021
662021
Migratory and dancing macrophage subsets in atherosclerotic lesions
S McArdle, K Buscher, Y Ghosheh, AB Pramod, J Miller, H Winkels, ...
Circulation research 125 (12), 1038-1051, 2019
622019
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function
M Bianchini, J Duchêne, D Santovito, MJ Schloss, M Evrard, H Winkels, ...
Science immunology 4 (36), eaar3054, 2019
622019
Heterogeneity of T cells in atherosclerosis defined by single-cell RNA-sequencing and cytometry by time of flight
H Winkels, D Wolf
Arteriosclerosis, thrombosis, and vascular biology 41 (2), 549-563, 2021
572021
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease
M Lacy, C Bürger, A Shami, M Ahmadsei, H Winkels, K Nitz, CM van Tiel, ...
Nature communications 12 (1), 3754, 2021
512021
The enzymatic and non-enzymatic function of myeloperoxidase (MPO) in inflammatory communication
Y Kargapolova, S Geißen, R Zheng, S Baldus, H Winkels, M Adam
Antioxidants 10 (4), 562, 2021
512021
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