A novel glycosphingolipid-degrading enzyme cleaves the linkage between the oligosaccharide and ceramide of neutral and acidic glycosphingolipids. M Ito, T Yamagata Journal of Biological Chemistry 261 (30), 14278-14282, 1986 | 208 | 1986 |
Ceramide/sphingosine/sphingosine 1-phosphate metabolism on the cell surface and in the extracellular space M Tani, M Ito, Y Igarashi Cellular signalling 19 (2), 229-237, 2007 | 205 | 2007 |
Ceramidase activity in bacterial skin flora as a possible cause of ceramide deficiency in atopic dermatitis Y Ohnishi, N Okino, M Ito, S Imayama Clinical Diagnostic Laboratory Immunology 6 (1), 101-104, 1999 | 178 | 1999 |
Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers N Fujitani, J Furukawa, K Araki, T Fujioka, Y Takegawa, J Piao, T Nishioka, ... Proceedings of the National Academy of Sciences 110 (6), 2105-2110, 2013 | 172 | 2013 |
Purification and characterization of glycosphingolipid-specific endoglycosidases (endoglycoceramidases) from a mutant strain of Rhodococcus sp: evidence for three molecular … M Ito, T Yamagata Journal of Biological Chemistry 264 (16), 9510-9519, 1989 | 170 | 1989 |
The reverse activity of human acid ceramidase N Okino, X He, S Gatt, K Sandhoff, M Ito, EH Schuchman Journal of Biological Chemistry 278 (32), 29948-29953, 2003 | 169 | 2003 |
Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets M Tani, T Sano, M Ito, Y Igarashi Journal of lipid research 46 (11), 2458-2467, 2005 | 135 | 2005 |
Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney S Mitsutake, M Tani, N Okino, K Mori, S Ichinose, A Omori, H Iida, ... Journal of Biological Chemistry 276 (28), 26249-26259, 2001 | 126 | 2001 |
Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase: a novel but highly conserved gene family of neutral/alkaline ceramidases M Tani, N Okino, T Tanigawa, H Izu, K Mori, M Ito Journal of Biological Chemistry 275 (15), 11229-11234, 2000 | 125 | 2000 |
Purification and Characterization of a Novel Ceramidase fromPseudomonas aeruginosa N Okino, M Tani, S Imayama, M Ito Journal of Biological Chemistry 273 (23), 14368-14373, 1998 | 124 | 1998 |
A Novel Enzyme That Cleaves the N-Acyl Linkage of Ceramides in Various Glycosphingolipids as Well as Sphingomyelin to Produce Their Lyso Forms (∗) M Ito, T Kurita, K Kita Journal of Biological Chemistry 270 (41), 24370-24374, 1995 | 119 | 1995 |
Klotho-related protein is a novel cytosolic neutral β-glycosylceramidase Y Hayashi, N Okino, Y Kakuta, T Shikanai, M Tani, H Narimatsu, M Ito Journal of biological chemistry 282 (42), 30889-30900, 2007 | 110 | 2007 |
Purification and characterization of a neutral ceramidase from mouse liver: a single protein catalyzes the reversible reaction in which ceramide is both hydrolyzed and synthesized M Tani, N Okino, S Mitsutake, T Tanigawa, H Izu, M Ito Journal of Biological Chemistry 275 (5), 3462-3468, 2000 | 101 | 2000 |
Molecular cloning, sequencing, and expression of the gene encoding alkaline ceramidase from Pseudomonas aeruginosa: cloning of a ceramidase homologue from Mycobacterium … N Okino, S Ichinose, A Omori, S Imayama, T Nakamura, M Ito Journal of Biological Chemistry 274 (51), 36616-36622, 1999 | 92 | 1999 |
Bipotential roles of ceramide in the growth of hippocampal neurons: Promotion of cell survival and dendritic outgrowth in dose‐and developmental stage–dependent manners J Mitoma, M Ito, S Furuya, Y Hirabayashi Journal of neuroscience research 51 (6), 712-722, 1998 | 92 | 1998 |
Extracellular polysaccharide-protein complexes of a harmful alga mediate the allelopathic control it exerts within the phytoplankton community Y Yamasaki, T Shikata, A Nukata, S Ichiki, S Nagasoe, T Matsubara, ... The ISME journal 3 (7), 808-817, 2009 | 87 | 2009 |
Extracellular secretion of phenolic substances from living brown algae T Shibata, Y Hama, T Miyasaki, M Ito, T Nakamura Journal of Applied Phycology 18, 787-794, 2006 | 87 | 2006 |
O-glycosylation of mucin-like domain retains the neutral ceramidase on the plasma membranes as a type II integral membrane protein M Tani, H Iida, M Ito Journal of Biological Chemistry 278 (12), 10523-10530, 2003 | 86 | 2003 |
Crystal Structure of Vibrionaceae Photobacterium sp. JT-ISH-224 α2,6-Sialyltransferase in a Ternary Complex With Donor Product CMP and Acceptor Substrate … Y Kakuta, N Okino, H Kajiwara, M Ichikawa, Y Takakura, M Ito, ... Glycobiology 18 (1), 66-73, 2008 | 80 | 2008 |
Isolation and characterization of a keratan sulfate-degrading endo-beta-galactosidase from Flavobacterium keratolyticus. M Kitamikado, M Ito, YT Li Journal of Biological Chemistry 256 (8), 3906-3909, 1981 | 80 | 1981 |