Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6 DJ Tyrrell, DR Goldstein Nature Reviews Cardiology 18 (1), 58-68, 2021 | 281 | 2021 |
Age-associated mitochondrial dysfunction accelerates atherogenesis DJ Tyrrell, MG Blin, J Song, SC Wood, M Zhang, DA Beard, DR Goldstein Circulation research 126 (3), 298-314, 2020 | 147 | 2020 |
Pathophysiology of heart failure and frailty: a common inflammatory origin? L Bellumkonda, D Tyrrell, SL Hummel, DR Goldstein Aging cell 16 (3), 444-450, 2017 | 107 | 2017 |
Respirometric profiling of muscle mitochondria and blood cells are associated with differences in gait speed among community-dwelling older adults DJ Tyrrell, MS Bharadwaj, CG Van Horn, SB Kritchevsky, BJ Nicklas, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2015 | 100 | 2015 |
Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health DJ Tyrrell, MS Bharadwaj, MJ Jorgensen, TC Register, AJA Molina Redox biology 10, 65-77, 2016 | 94 | 2016 |
Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults DJ Tyrrell, MS Bharadwaj, CG Van Horn, AP Marsh, BJ Nicklas, ... Experimental gerontology 70, 84-91, 2015 | 76 | 2015 |
Blood‐based bioenergetic profiling reflects differences in brain bioenergetics and metabolism DJ Tyrrell, MS Bharadwaj, MJ Jorgensen, TC Register, C Shively, ... Oxidative Medicine and Cellular Longevity 2017 (1), 7317251, 2017 | 61 | 2017 |
Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults MS Bharadwaj, DJ Tyrrell, I Leng, JL Demons, MF Lyles, JJ Carr, ... BMC obesity 2, 1-11, 2015 | 37 | 2015 |
Preparation and respirometric assessment of mitochondria isolated from skeletal muscle tissue obtained by percutaneous needle biopsy MS Bharadwaj, DJ Tyrrell, MF Lyles, JL Demons, GW Rogers, AJA Molina JoVE (Journal of Visualized Experiments), e52350, 2015 | 35 | 2015 |
Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis G Hindy, DJ Tyrrell, A Vasbinder, C Wei, F Presswalla, H Wang, P Blakely, ... The Journal of clinical investigation 132 (24), 2022 | 33 | 2022 |
Aging impairs mitochondrial function and mitophagy and elevates interleukin 6 within the cerebral vasculature DJ Tyrrell, MG Blin, J Song, SC Wood, DR Goldstein Journal of the American Heart Association 9 (23), e017820, 2020 | 27 | 2020 |
Macrophage migration inhibitory factor enhances influenza-associated mortality in mice CA Smith, DJ Tyrell, UA Kulkarni, S Wood, L Leng, RL Zemans, R Bucala, ... JCI insight 4 (13), 2019 | 18 | 2019 |
Aging alters the aortic proteome in health and thoracic aortic aneurysm DJ Tyrrell, J Chen, BY Li, SC Wood, W Rosebury-Smith, HA Remmer, ... Arteriosclerosis, thrombosis, and vascular biology 42 (8), 1060-1076, 2022 | 13 | 2022 |
Age‐associated adipose tissue inflammation promotes monocyte chemotaxis and enhances atherosclerosis J Song, D Farris, P Ariza, S Moorjani, M Varghese, M Blin, J Chen, ... Aging Cell 22 (2), e13783, 2023 | 10 | 2023 |
Itaconate suppresses atherosclerosis by activating a Nrf2-dependent antiinflammatory response in macrophages in mice J Song, Y Zhang, RA Frieler, A Andren, S Wood, DJ Tyrrell, ... The Journal of Clinical Investigation 134 (3), 2024 | 6 | 2024 |
Cardiovascular aging: spotlight on mitochondria MA Ali, R Gioscia-Ryan, D Yang, NR Sutton, DJ Tyrrell American Journal of Physiology-Heart and Circulatory Physiology 326 (2 …, 2024 | 4 | 2024 |
Clonally expanded memory CD8+ T cells accumulate in atherosclerotic plaques and are pro-atherogenic in aged mice DJ Tyrrell, KM Wragg, J Chen, H Wang, J Song, MG Blin, C Bolding, ... Nature Aging 3 (12), 1576-1590, 2023 | 4 | 2023 |
Mitochondrial respiratory states and rates: building blocks of mitochondrial physiology E Gnaiger Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859, e54-e55, 2018 | 3* | 2018 |
Aging Enhances Vascular Mitochondrial Dysfunction Prior to Hyperlipidemia to Accelerate Atherosclerosis D Tyrrell, DR Goldstein Circulation 140 (Suppl_1), A12990-A12990, 2019 | 2 | 2019 |
Analysis of NIH K99/R00 awards and the career progression of awardees NC Woitowich, SR Hengel, C Solis, TP Vilgalys, J Babdor, DJ Tyrrell Elife 12, RP88984, 2024 | 1 | 2024 |