Peptide binding to HLA‐DR1: a peptide with most residues substituted to alanine retains MHC binding. TS Jardetzky, JC Gorga, R Busch, J Rothbard, JL Strominger, DC Wiley The EMBO journal 9 (6), 1797-1803, 1990 | 316 | 1990 |
Measurement of protein turnover rates by heavy water labeling of nonessential amino acids R Busch, YK Kim, RA Neese, V Schade-Serin, M Collins, M Awada, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (5), 730-744, 2006 | 288 | 2006 |
Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression R Busch, CH Rinderknecht, S Roh, AW Lee, JJ Harding, T Burster, ... Immunological reviews 207 (1), 242-260, 2005 | 209 | 2005 |
Measurement of cell proliferation by heavy water labeling R Busch, RA Neese, M Awada, GM Hayes, MK Hellerstein Nature protocols 2 (12), 3045-3057, 2007 | 205 | 2007 |
Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum. R Busch, I Cloutier, RP Sékaly, GJ Hämmerling The EMBO journal 15 (2), 418-428, 1996 | 188 | 1996 |
Formation of a highly peptide-receptive state of class II MHC JD Rabinowitz, M Vrljic, PM Kasson, MN Liang, R Busch, JJ Boniface, ... Immunity 9 (5), 699-709, 1998 | 163 | 1998 |
Degenerate binding of immunogenic peptides to HLA-DR proteins on B cell surfaces R Busch, G Strang, K Howland, JB Rothbard International Immunology 2 (5), 443-451, 1990 | 155 | 1990 |
Accessory molecules for MHC class II peptide loading R Busch, RC Doebele, NS Patil, A Pashine, ED Mellins Current opinion in immunology 12 (1), 99-106, 2000 | 153 | 2000 |
Determination of the HLA-DM interaction site on HLA-DR molecules RC Doebele, R Busch, HM Scott, A Pashine, ED Mellins Immunity 13 (4), 517-527, 2000 | 151 | 2000 |
Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides A Pashine, R Busch, MP Belmares, JN Munning, RC Doebele, ... Immunity 19 (2), 183-192, 2003 | 131 | 2003 |
Effect of natural polymorphism at residue 86 of the HLA-DR beta chain on peptide binding. R Busch, CM Hill, JD Hayball, JR Lamb, JB Rothbard Journal of immunology (Baltimore, Md.: 1950) 147 (4), 1292-1298, 1991 | 125 | 1991 |
Developing and shedding inhibitions: how MHC class II molecules reach maturity R Busch, ED Mellins Current opinion in immunology 8 (1), 51-58, 1996 | 120 | 1996 |
Symptom-based stratification of patients with primary Sjögren's syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of randomised … JR Tarn, N Howard-Tripp, DW Lendrem, X Mariette, A Saraux, ... The Lancet Rheumatology 1 (2), e85-e94, 2019 | 115 | 2019 |
The kinetic basis of peptide exchange catalysis by HLA-DM JA Zarutskie, R Busch, Z Zavala-Ruiz, M Rushe, ED Mellins, LJ Stern Proceedings of the National Academy of Sciences 98 (22), 12450-12455, 2001 | 92 | 2001 |
Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression K Ladell, MK Hellerstein, D Cesar, R Busch, D Boban, JM McCune The Journal of Immunology 180 (12), 7907-7918, 2008 | 91 | 2008 |
Structural factors contributing to DM susceptibility of MHC class II/peptide complexes MP Belmares, R Busch, KW Wucherpfennig, HM McConnell, ED Mellins The Journal of Immunology 169 (9), 5109-5117, 2002 | 82 | 2002 |
The TRACTISS Protocol: a randomised double blind placebo controlled clinical TRial of Anti-B-Cell Therapy In patients with primary Sjögren’s Syndrome S Brown, N Navarro Coy, C Pitzalis, P Emery, S Pavitt, J Gray, C Hulme, ... BMC musculoskeletal disorders 15, 1-10, 2014 | 74 | 2014 |
Secondary structure composition and pH-dependent conformational changes of soluble recombinant HLA-DM R Busch, Z Reich, DM Zaller, V Sloan, ED Mellins Journal of Biological Chemistry 273 (42), 27557-27564, 1998 | 73 | 1998 |
Structural analysis of a peptide-HLA class II complex: identification of critical interactions for its formation and recognition by T cell receptor JB Rothbard, R Busch, K Howland, V Bal, C Fenton, WR Taylor, JR Lamb International immunology 1 (5), 479-486, 1989 | 70 | 1989 |
Measurement of brain microglial proliferation rates in vivo in response to neuroinflammatory stimuli: application to drug discovery M Shankaran, ME Marino, R Busch, C Keim, C King, J Lee, S Killion, ... Journal of neuroscience research 85 (11), 2374-2384, 2007 | 66 | 2007 |