PET imaging of microglial activation—beyond targeting TSPO B Janssen, DJ Vugts, AD Windhorst, RH Mach Molecules 23 (3), 607, 2018 | 117 | 2018 |
Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis W Beaino, B Janssen, G Kooij, SMA van der Pol, B van Het Hof, ... Journal of neuroinflammation 14, 1-16, 2017 | 109 | 2017 |
Imaging of neuroinflammation in Alzheimer's disease, multiple sclerosis and stroke: Recent developments in positron emission tomography B Janssen, DJ Vugts, U Funke, GT Molenaar, PS Kruijer, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (3), 425-441, 2016 | 80 | 2016 |
Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [11C] A‐740003 as a novel tracer of neuroinflammation B Janssen, DJ Vugts, U Funke, A Spaans, RC Schuit, E Kooijman, ... Journal of Labelled Compounds and Radiopharmaceuticals 57 (8), 509-516, 2014 | 79 | 2014 |
Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation B Janssen, DJ Vugts, SM Wilkinson, D Ory, S Chalon, JJM Hoozemans, ... Scientific reports 8 (1), 6580, 2018 | 64 | 2018 |
The P2X7 receptor tracer [11C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study MHJ Hagens, SSV Golla, B Janssen, DJ Vugts, W Beaino, AD Windhorst, ... European journal of nuclear medicine and molecular imaging 47, 379-389, 2020 | 54 | 2020 |
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state A Villa, B Klein, B Janssen, J Pedragosa, G Pepe, B Zinnhardt, DJ Vugts, ... Theranostics 8 (19), 5400, 2018 | 48 | 2018 |
Pharmacological Evaluation of Novel Bioisosteres of an Adamantanyl Benzamide P2X7 Receptor Antagonist SM Wilkinson, ML Barron, J O’Brien-Brown, B Janssen, L Stokes, ... ACS chemical neuroscience 8 (11), 2374-2380, 2017 | 44 | 2017 |
Development of brain PET imaging agents: Strategies for imaging neuroinflammation in Alzheimer's disease B Janssen, RH Mach Progress in molecular biology and translational science 165, 371-399, 2019 | 39 | 2019 |
Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening JJ Ferrie, Z Lengyel-Zhand, B Janssen, MG Lougee, S Giannakoulias, ... Chemical science 11 (47), 12746-12754, 2020 | 36 | 2020 |
Synthesis and characterization of high affinity fluorogenic α-synuclein probes Z Lengyel-Zhand, JJ Ferrie, B Janssen, CJ Hsieh, T Graham, K Xu, ... Chemical Communications 56 (24), 3567-3570, 2020 | 36 | 2020 |
Towards PET imaging of the dynamic phenotypes of microglia W Beaino, B Janssen, DJ Vugts, HE de Vries, AD Windhorst Clinical & Experimental Immunology 206 (3), 282-300, 2021 | 30 | 2021 |
11C‐labeled and 18F‐labeled PET ligands for subtype‐specific imaging of histamine receptors in the brain U Funke, DJ Vugts, B Janssen, A Spaans, PS Kruijer, AA Lammertsma, ... Journal of Labelled Compounds and Radiopharmaceuticals 56 (3-4), 120-129, 2013 | 24 | 2013 |
PET imaging of P2X7R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [11C]SMW139 W Beaino, B Janssen, E Kooijman, R Vos, RC Schuit, J O’Brien-Brown, ... Journal of neuroinflammation 17, 1-18, 2020 | 18 | 2020 |
Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the Brain B van der Wildt, B Janssen, A Pekošak, EJL Stéen, RC Schuit, ... ACS Chemical Neuroscience 12 (23), 4465-4474, 2021 | 15 | 2021 |
Initial evaluation of P2X (7) R antagonists [C-11] A-740003 and [C-11] SMW64-D16 as PET tracers of microglial activation in neuroinflammation B Janssen, D Ory, SM Wilkinson, DJ Vugts, EJ Kooijman, J Verbeek, ... JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 58, S277-S277, 2015 | 5 | 2015 |
PET imaging of purinergic receptors B Janssen, DJ Vugts, AD Windhorst PET and SPECT of Neurobiological Systems, 879-889, 2021 | 4 | 2021 |
Synthesis of the first carbon-11 labelled P2Y (12) receptor antagonist for PET imaging of microglial activation in neuroinflammation B Janssen, DJ Vugts, U Funke, GT Molenaar, PS Kruijer, F Dolle, ... JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 58, S44-S44, 2015 | 3* | 2015 |
Imaging histamine receptors using PET and SPECT U Funke, DJ Vugts, B Janssen, A Spaans, PS Kruijer, AA Lammertsma, ... PET and SPECT of Neurobiological Systems, 331-376, 2014 | 3 | 2014 |
Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search B Janssen, G Tian, Z Lengyel-Zhand, CJ Hsieh, MG Lougee, A Riad, K Xu, ... Molecular Imaging and Biology 25 (4), 704-719, 2023 | 2 | 2023 |