Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ... Cell 160 (4), 745-758, 2015 | 718 | 2015 |
Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation Z Xie, D Zhang, D Chung, Z Tang, H Huang, L Dai, S Qi, J Li, G Colak, ... Molecular Cell 62 (2), 194-206, 2016 | 486 | 2016 |
The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis JE Dominy Jr, Y Lee, MP Jedrychowski, H Chim, MJ Jurczak, ... Molecular Cell, 2012 | 311 | 2012 |
O-GlcNAc Transferase/Host Cell Factor C1 Complex Regulates Gluconeogenesis by Modulating PGC-1α Stability HB Ruan, X Han, MD Li, JP Singh, K Qian, S Azarhoush, L Zhao, ... Cell Metabolism 16 (2), 226-237, 2012 | 308 | 2012 |
Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity S Diano, ZW Liu, JK Jeong, MO Dietrich, HB Ruan, E Kim, S Suyama, ... Nature medicine 17 (9), 1121-1127, 2011 | 302 | 2011 |
O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat HB Ruan, MO Dietrich, ZW Liu, MR Zimmer, MD Li, JP Singh, K Zhang, ... Cell 159 (2), 306-317, 2014 | 275 | 2014 |
Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression Y Lee, JE Dominy, YJ Choi, M Jurczak, N Tolliday, JP Camporez, H Chim, ... Nature 510 (7506), 547-551, 2014 | 249 | 2014 |
Cracking the O-GlcNAc code in metabolism HB Ruan, JP Singh, MD Li, J Wu, X Yang Trends in Endocrinology & Metabolism 24 (6), 301-309, 2013 | 243 | 2013 |
O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination MD Li, HB Ruan, ME Hughes, JS Lee, JP Singh, SP Jones, MN Nitabach, ... Cell metabolism 17 (2), 303-310, 2013 | 213 | 2013 |
Regulation of protein degradation by O-GlcNAcylation: crosstalk with ubiquitination HB Ruan, Y Nie, X Yang Molecular & Cellular Proteomics 12 (12), 3489-3497, 2013 | 166 | 2013 |
Calcium-dependent O-GlcNAc signaling drives liver autophagy in adaptation to starvation HB Ruan, Y Ma, S Torres, B Zhang, C Feriod, RM Heck, K Qian, M Fu, X Li, ... Genes & development 31 (16), 1655-1665, 2017 | 121 | 2017 |
Gut microbiota profiling in Han Chinese with type 1 diabetes Y Huang, SC Li, J Hu, HB Ruan, HM Guo, HH Zhang, X Wang, YF Pei, ... Diabetes research and clinical practice 141, 256-263, 2018 | 97 | 2018 |
The lineage stability and suppressive program of regulatory T cells require protein O-GlcNAcylation B Liu, OC Salgado, S Singh, KL Hippen, JC Maynard, AL Burlingame, ... Nature communications 10 (1), 354, 2019 | 95 | 2019 |
Transcriptional regulation of O-GlcNAc homeostasis is disrupted in pancreatic cancer K Qian, S Wang, M Fu, J Zhou, JP Singh, MD Li, Y Yang, K Zhang, J Wu, ... Journal of Biological Chemistry 293 (36), 13989-14000, 2018 | 82 | 2018 |
MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels A Nagarajan, MC Petersen, AR Nasiri, G Butrico, A Fung, HB Ruan, ... Nature communications 7 (1), 12639, 2016 | 77 | 2016 |
Ketone bodies as epigenetic modifiers HB Ruan, PA Crawford Current Opinion in Clinical Nutrition & Metabolic Care 21 (4), 260-266, 2018 | 70 | 2018 |
Hepatic inositol 1, 4, 5 trisphosphate receptor type 1 mediates fatty liver CN Feriod, A Gustavo Oliveira, MT Guerra, L Nguyen, K Mitchell Richards, ... Hepatology Communications 1 (1), 23-35, 2017 | 67 | 2017 |
Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C M Zhao, K Ren, X Xiong, Y Xin, Y Zou, JC Maynard, A Kim, AP Battist, ... Immunity 55 (4), 623-638. e5, 2022 | 62 | 2022 |
Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity [S] C Bindesbøll, Q Fan, RC Nørgaard, L MacPherson, HB Ruan, J Wu, ... Journal of lipid research 56 (4), 771-785, 2015 | 56 | 2015 |
Identification of a novel point mutation of mouse proto-oncogene c-kit through N-ethyl-N-nitrosourea mutagenesis HB Ruan, N Zhang, X Gao Genetics 169 (2), 819-831, 2005 | 54 | 2005 |