Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer B Chen, ME Dodge, W Tang, J Lu, Z Ma, CW Fan, S Wei, W Hao, J Kilgore, ... Nature chemical biology 5 (2), 100-107, 2009 | 1605 | 2009 |
Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts: many raft proteins are acylated, while few are prenylated KA Melkonian, AG Ostermeyer, JZ Chen, MG Roth, DA Brown Journal of Biological Chemistry 274 (6), 3910-3917, 1999 | 842 | 1999 |
Interaction of influenza virus haemagglutinin with sphingolipid–cholesterol membrane domains via its transmembrane domain P Scheiffele, MG Roth, K Simons The EMBO journal, 1997 | 837 | 1997 |
Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi YJ Wang, J Wang, HQ Sun, M Martinez, YX Sun, E Macia, T Kirchhausen, ... Cell 114 (3), 299-310, 2003 | 630 | 2003 |
Phosphatidylinositol 4, 5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3 AL Rozelle, LM Machesky, M Yamamoto, MHE Driessens, RH Insall, ... Current Biology 10 (6), 311-320, 2000 | 628 | 2000 |
Synthetic lethal screen identification of chemosensitizer loci in cancer cells AW Whitehurst, BO Bodemann, J Cardenas, D Ferguson, L Girard, ... Nature 446 (7137), 815-819, 2007 | 582 | 2007 |
Targeting QseC signaling and virulence for antibiotic development DA Rasko, CG Moreira, DR Li, NC Reading, JM Ritchie, MK Waldor, ... Science 321 (5892), 1078-1080, 2008 | 578 | 2008 |
Image-based genome-wide siRNA screen identifies selective autophagy factors A Orvedahl, R Sumpter Jr, G Xiao, A Ng, Z Zou, Y Tang, M Narimatsu, ... Nature 480 (7375), 113-117, 2011 | 505 | 2011 |
Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles. NT Ktistakis, HA Brown, MG Waters, PC Sternweis, MG Roth The Journal of cell biology 134 (2), 295-306, 1996 | 481 | 1996 |
Phosphoinositides in constitutive membrane traffic MG Roth Physiological reviews 84 (3), 699-730, 2004 | 382 | 2004 |
A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin. CB Brewer, MG Roth The Journal of cell biology 114 (3), 413-421, 1991 | 349 | 1991 |
The liver X receptor ligand T0901317 decreases amyloid β production in vitro and in a mouse model of Alzheimer's disease RP Koldamova, IM Lefterov, M Staufenbiel, D Wolfe, S Huang, ... Journal of Biological Chemistry 280 (6), 4079-4088, 2005 | 324 | 2005 |
A single amino acid change in the cytoplasmic domain allows the influenza virus hemagglutinin to be endocytosed through coated pits J Lazarovits, M Roth Cell 53 (5), 743-752, 1988 | 294 | 1988 |
Different biosynthetic transport routes to the plasma membrane in BHK and CHO cells. T Yoshimori, P Keller, MG Roth, K Simons The Journal of cell biology 133 (2), 247-256, 1996 | 274 | 1996 |
Differential extractability of influenza virus hemagglutinin during intracellular transport in polarized epithelial cells and nonpolar fibroblasts. JE Skibbens, MG Roth, KS Matlin The Journal of cell biology 108 (3), 821-832, 1989 | 254 | 1989 |
High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase J Baldwin, CH Michnoff, NA Malmquist, J White, MG Roth, PK Rathod, ... Journal of Biological Chemistry 280 (23), 21847-21853, 2005 | 252 | 2005 |
Mutations in the middle of the transmembrane domain reverse the polarity of transport of the influenza virus hemagglutinin in MDCK epithelial cells S Lin, HY Naim, A Chapin Rodriguez, MG Roth The Journal of cell biology 142 (1), 51-57, 1998 | 251 | 1998 |
Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A. NT Ktistakis, HA Brown, PC Sternweis, MG Roth Proceedings of the National Academy of Sciences 92 (11), 4952-4956, 1995 | 247 | 1995 |
Characteristics of the tyrosine recognition signal for internalization of transmembrane surface glycoproteins. NT Ktistakis, D Thomas, MG Roth The Journal of cell biology 111 (4), 1393-1407, 1990 | 236 | 1990 |
A genome-wide RNAi screen for Wnt/β-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer W Tang, M Dodge, D Gundapaneni, C Michnoff, M Roth, L Lum Proceedings of the National Academy of Sciences 105 (28), 9697-9702, 2008 | 209 | 2008 |